点击访问GeneHero™ Cas9 稳定表达细胞系、GeneHero™ CRISPRa预制稳转株、GeneHero™ CRISPRi 预制稳转株、预制肿瘤细胞稳转株产品页面
- Elste, J., et al. (2023). Plant Cell-Engineered Gold Nanoparticles Conjugated to Quercetin Inhibit SARS-CoV-2 and HSV-1 Entry. Int J Mol Sci. doi: 10.3390/ijms241914792 [Lentifect™ SARS-CoV-2 D614G Spike-Pseudotyped Lentiviral Particles; Lenti-Pac™ HEK293T cell line]
- Grimes, S.M., et al. (2023). Single-cell multi-gene identification of somatic mutations and gene rearrangements in cancer. NAR Cancer doi: 10.1093/narcan/zcad034 [GeneHero™ Jurkat Cas9-expressing stable cell line]
- Shin, S.M., et al. (2023). Peripheral sensory neurons and non-neuronal cells express functional Piezo1 channels. Mol Pain doi: 10.1177/17448069231174315 [GeneHero™ Neuro2a Cas9-expressing stable cell line]
- Kuroda, T., et al. (2023). Efficacy comparison of 3CL protease inhibitors ensitrelvir and nirmatrelvir against SARS-CoV-2 in vitro and in vivo. J Antimicrob Chemother doi: 10.1093/jac/dkad027 [ACE2 and TMPRSS2-expressing HEK293T cells]
- Morimoto, M., et al. (2023). Bi-allelic ATG4D variants are associated with a neurodevelopmental disorder characterized by speech and motor impairment. NPJ Genom Med doi: 10.1038/s41525-022-00343-8 [GeneHero™ HeLa Cas9-expressing stable cell line]
- Osaka, T., et al. (2023). Cross-Reactivity of Antibodies in Intravenous Immunoglobulin Preparation for Protection against SARS-CoV-2. Microorganisms doi: 10.3390/microorganisms11020471 [ACE2- and TMPRSS2-expressing HEK293T stable cell line]
- Chan, J.F-K., et al. (2023). Altered host protease determinants for SARS-CoV-2 Omicron. Sci Adv doi: 10.1126/sciadv.add3867 [ACE2-expressing HEK293T stable cell line]
- Koch, J., et al. (2023). Establishing a New Platform to Investigate the Efficacy of Oncolytic Virotherapy in a Human Ex Vivo Peritoneal Carcinomatosis Model. Viruses doi: 10.3390/v15020363 [GFP dual-labeled HT-29 cancer cell line]
- Merluza, J., et al. (2023). Validation and Establishment of the SARS-CoV-2 Lentivirus Surrogate Neutralization Assay as a Prescreening Tool for the Plaque Reduction Neutralization Test. Microbiol Spectr doi: 10.1128/spectrum.03789-22 [ACE2- and TMPRSS2-expressing HEK293T stable cell line]
- Nakata, Y., et al. (2023). Cellular APOBEC3A deaminase drives mutations in the SARS-CoV-2 genome. Nucleic Acids Res doi: 10.1093/nar/gkac1238 [ACE2- and TMPRSS2-expressing HEK293T stable cell line]
- Chen, Y.A., et al. (2022). In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model. Gene Ther doi: 10.1038/s41434-022-00375-w [GeneHero™ HeLa Cas9-expressing stable cell line]
- Travis, B.J., et al. (2022). Significance of chlorine‐dioxide‐based oral rinses in preventing SARS‐CoV‐2 cell entry. Oral Dis doi: 10.1111/odi.14319 [ACE2-expressing HEK293T stable cell line; Lentifect™ SARS-CoV-2 D614G Spike-Pseudotyped Lentiviral Particles]
- Wang, X., et al. (2022). Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis. Neuron doi: 10.1016/j.neuron.2022.10.028 [Neuro2a stably expressing Cas9 from ROSA26 site]
- Zhang, W.F., et al. (2022). SIRT1 inactivation switches reactive astrocytes to an antiinflammatory phenotype in CNS autoimmunity. J Clin Invest doi: 10.1172/JCI151803 [Neuro2a stably expressing Cas9 from ROSA26 site]
- Moreau, F., et al. (2022). Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural antagonist. Nat Commun doi: 10.1038/s41467-022-34391-6 [GFP dual-labeled MCF7 cancer cell line]
- Kim, Y.S., et al. (2022). Mulberry Component Kuwanon C Exerts Potent Therapeutic Efficacy In Vitro against COVID-19 by Blocking the SARS-CoV-2 Spike S1 RBD:ACE2 Receptor Interaction. Int J Mol Sci doi: 10.3390/ijms232012516 [ACE2- and TMPRSS2-expressing HEK293T stable cell line]
- Kim, Y.S., et al. (2022). Mulberrofuran G; a Mulberry Component; Prevents SARS-CoV-2 Infection by Blocking the Interaction between SARS-CoV-2 Spike Protein S1 Receptor-Binding Domain and Human Angiotensin-Converting Enzyme 2 Receptor. Nutrients doi: 10.3390/nu14194170 [ACE2- and TMPRSS2-expressing HEK293T stable cell line]
- Luo, W.S., et al. (2022). Pcdh11x controls target specification of mossy fiber sprouting. Front Neurosci doi: 10.3389/fnins.2022.888362 [Mouse cell line Neuro2a stably expressing Cas9 from ROSA26 site]
- Han, S.T., et al. (2022). PUS7 deficiency in human patients causes profound neurodevelopmental phenotype by dysregulating protein translation. Molecular Genetics and Metabolism doi: 10.1016/j.ymgme.2022.01.103 [GeneHero™ HeLa Cas9-expressing stable cell line]
- Hwang, J-Y., et al. (2022). Humoral and Cellular Responses to COVID-19 Vaccines in SARS-CoV-2 Infection-Naïve and -Recovered Korean Individuals. Vaccines doi: 10.3390/vaccines10020332 [ACE2-expressing HEK293T stable cell line]
- Fereydouni, M., et al. (2022). Human Tumor Targeted Cytotoxic Mast Cells for Cancer Immunotherapy. Frontiers in Oncology doi: 10.3389/fonc.2022.871390 [Luciferase + GFP labeled SK-BR-3 cell line]
- Park, H., et al. (2022). TMED3 Complex Mediates ER Stress-Associated Secretionof CFTR, Pendrin, and SARS-CoV-2 Spike. Advanced Science doi: 10.1002/advs.202105320 [ACE2- and TMPRSS2-expressing HEK293T stable cell line]
- Sim, J-R., et al. (2022). Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition. Cell Reports doi: 10.1016/j.celrep.2022.111117 [ACE2- and TMPRSS2-expressing HEK293T stable cell line]
- Grodzki, M., et al. (2022). Genome-scale CRISPR screens identify host factors that promote human coronavirus infection. Genome Medicine doi: 10.1186/s13073-022-01013-1 [ACE2-expressing HEK293T stable cell line]
- Ariumi, Y. (2022). Host Cellular RNA Helicases Regulate SARS-CoV-2 Infection. Journal of Virology doi: 10.1128/jvi.00002 [ACE2-expressing HEK293T stable cell line]
- Pivniouk, V., et al. (2022). The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression. Journal of Allergy and Clinical Immunology doi: 10.1016/j.jaci.2021.11.019 [ACE2-expressing HEK293T stable cell line]
- Travis, B.J., et al. (2022). Significance of chlorine-dioxide-based oral rinses in preventing SARS-CoV-2 cell entry. Oral Diseases doi: 10.1111/odi.14319 [ACE2-expressing HEK293T stable cell line]
- Zheng, W., et al. (2022). SIRT1 inactivation switches reactive astrocytes to an anti-inflammatory phenotype in CNS autoimmunity. The Journal of Clinical Investigation doi: 10.1172/JCI151803 [GeneHero™ Neuro2a Cas9-expressing stable cell line]
- Hashizume, M., et al. (2021). Population-Specific ACE2 Single-Nucleotide Polymorphisms Have Limited Impact on SARS-CoV-2 Infectivity In Vitro. Viruses doi: 10.3390/v13010067 [ACE2-expressing HEK293T stable cell line]
- Hana, S., et al. (2021) Highly efficient neuronal gene knockout in vivo by CRISPR-Cas9 via neonatal intracerebroventricular injection of AAV in mice. Gene Thereapy doi: 10.1038/s41434-021-00224-2 [GeneHero™ HeLa, Neuro2a Cas9-expressing stable cell lines]
- Beitzel, B.F., et al. (2021). On‐Demand Patient‐Specific Phenotype‐to‐Genotype Ebola Virus Characterization. Viruses doi: 10.3390/ v13102010 [Custom stable cell line services]
- Paidi, R.K., et al. (2021). Eugenol, a Component of Holy Basil (Tulsi) and Common Spice Clove, Inhibits the Interaction Between SARS-CoV-2 Spike S1 and ACE2 to Induce Therapeutic Responses. Journal of Neuroimmune Pharmacology doi: 10.1007/s11481-021-10028-1 [ACE2-expressing HEK293T stable cell line]
- Song, Y., et al. (2021). A genome-wide CRISPR/Cas9 gene knockout screen identifies immunoglobulin superfamily DCC subclass member 4 as a key host factor that promotes influenza virus endocytosis. PLOS Pathogens doi: 10.1371/journal.ppat.1010141 [GeneHero™ A549 Cas9-expressing stable cell line]
- Paidi, R.K., et al. (2021). Selective Inhibition of the Interaction between SARS-CoV-2 Spike S1 and ACE2 by SPIDAR Peptide Induces Anti-Inflammatory Therapeutic Responses. Journal of Immunology doi: 10.4049/jimmunol.2100144 [ACE2-expressing HEK293T stable cell line]
- Kasper, S.H., et al. (2020). Colorectal cancer-associated anaerobic bacteria proliferate in tumor spheroids and alter the microenvironment. Scientific Reports doi: 10.1038/s41598-020-62139-z [GFP labeled HT-29 cell line]
- Reznikov, L.R., et al. (2020). Identification of antiviral antihistamines for COVID-19 repurposing. Biochemical and Biophysical Research Communications doi: 10.1016/j.bbrc.2020.11.095 [ACE2-expressing HEK293T stable cell line]
- Pan, Y., et al. (2020). The nature of the modification at position 37 oftRNAPhecorrelates with acquired taxol resistance. Nucleic Acids Research doi: 10.1093/nar/gkaa1164 [TYW2 stable knockdown HeLa cell line]
- Chaudhari, H.G., et al. (2020). Evaluation of Homology-Independent CRISPR-Cas9Off-Target Assessment Methods. The CRISPR Journal doi: 10.1089/crispr.2020.0053 [GeneHero™ HEK293 Cas9-expressing stable cell line]
- Howell, M.C., et al. (2019). Lung cancer cells survive epidermal growth factor receptor tyrosine kinase inhibitor exposure through upregulation of cholesterol synthesis. FASEB Bio Advances doi: 10.1096/fba.2019-00081 [GFP labeled H1975 cell line]
- Sokhi, U.K., et al. (2018). Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models. Nature Communications. DOI: 10.1038/s41467-018-03081-7. [HEK293 Cas9-expressing stable cell line]
- Zhao, D., et al. (2018). Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis. Molecular Cell. DOI: 10.1016/j.molcel.2018.01.017. [HeLa, HEK293 and A549 Cas9-expressing stable cell lines]
- Shen, J.P., et al. (2017). Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions. Nature Methods doi 10.1038/nmeth.4225. [HeLa, HEK293 and A549 Cas9-expressing stable cell lines]
- Mitchell, M.J., et al. (2017). Polymeric mechanical amplifiers of immune cytokine-mediated apoptosis. Nature Communications. DOI: 10.1038/ncomms14179. [dual-labelled luciferase and GFP+ COLO 205 colon cancer cell line]
