ORF/cDNA克隆库—完善的基因表达研究解决方案

GeneCopoeia是NCBI推荐的基因克隆供应商之一，提供多种基因克隆产品，以满足广大顾客多元化的需求。

基因和蛋白的过表达实验广泛用于基因组学、蛋白质组学、和系统生物学的研究。但是要获得即用型表达克隆需要复杂的克隆、验证和序列分析的过程。 GeneCopoeia提供多种表达系统、启动子克隆、融合标签及筛选标记，客户可以定制或购买预制的即用型表达克隆。所有ORF与cDNA克隆序列均经过验证，可用于即时表达。

ORF/cDNA克隆选购指导:

	Option 1 最佳选择	Option 2 高效选择	Option 3 较好选择	Option 4 经济选择
Products	OmicsLink™ 即用型ORF表达克隆	ORFEXPRESS™ Gateway® PLUS 穿梭克隆	ORFeome Collaboration Clones in Gateway® Entry Vector	GeneCopoeia 全长cDNA克隆
主要区别	即买即用省时省力	需要亚克隆步骤	需要亚克隆步骤无多克隆位点	需要亚克隆步骤包含5’和 3’ UTRs
独特之处	全长测序 100多种载体 50多种标签多种启动子可选没有 5’和 3’UTR	包含多克隆位点包含核糖体结合位点 (Shine-Dalgarno 或Kozak 序列) 没有 5’和 3’UTR	包含Kozak 序列没有 5’和 3’UTR	全长转录本，含有5’和 3’ UTR
优势	可直接用于蛋白表达无需亚克隆步骤优化的蛋白翻译骨架设计应用广泛省时省力	(与传统的 Gateway®or ORFeome 克隆相比) 对于重组和经典克隆都很方便优化的蛋白翻译骨架设计	可用于重组克隆	经济
不足		(与OmicsLink Expression-Ready克隆相比) 需要繁琐的克隆步骤无启动子(不能直接表达) 需要购买配套载体才能表达需要验证需要额外的时间和花费	(与Gateway PLUS和 Expression-Ready克隆相比) 需要繁琐的克隆步骤无启动子(不能直接表达) 不适合在细菌里表达无多克隆位点购买配套载体才能表达需要验证需要额外的时间和花费	需要繁琐的克隆步骤无启动子(不能直接表达) 购买配套载体才能表达需要验证需要额外的时间和花费
	点击了解详情	点击了解详情	点击了解详情	点击了解详情

Expression-ready ORF cDNA clones

Cloning process from Gateway PLUS Shuttle ORF cDNA clones

Cloning process from full-length whole transcript cDNA clones

Read more – OmicsLink™ ORF cDNA brochure

2023已发表文献

Zheng, Y., et al. (2023). Chronic psychological stress promotes breast cancer pre-metastatic niche formation by mobilizing splenic MDSCs via TAM/CXCL1 signaling. J Exp Clin Cancer Res doi: 10.1186/s13046-023-02696-z [GLuc-ON™ promoter-reporter clone; Secrete-Pair™ Dual Luminescence Assay Kit; OMICSLINK™ Lentiviral ORF vector; polybrene reagent]
Quintanal-Villalonga, A., et al. (2023). Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers. SCIENCE TRANSLATIONAL MEDICINE doi: 10.1126/scitranslmed.adf7006 [GLuc-ON™ promoter-reporter clone; OMICSLINK™ ORF expression control clones]
Bergholz, J.S., et al. (2023). PI3Kβ controls immune evasion in PTEN-deficient breast tumours. Nature doi: 10.1038/s41586-023-05940-w [OMICSLINK™ mouse Pik3cb ORF expression clone]
Sanmarco, L.M., et al. (2023). Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells. Nature doi: 10.1038/s41586-023-06409-6 [OMICSLINK™ NDUFA4L2 ORF expression clone and empty control vector; Secrete-Pair™ Gaussia Luciferase Assay Kit]
Ke, H., et al. (2023). Landscape of pathogenic mutations in premature ovarian insufficiency. Nature Medicine doi: 10.1038/s41591-022-02194-3 [OMICSLINK™ empty vector; Secrete-Pair™ dual luminescence kit]
Jiang, L., et al. (2023). Chaperoning of specific tau structure by immunophilin FKBP12 regulates the neuronal resilience to extracellular stress. SCIENCE ADVANCES doi: 10.1126/sciadv.add9789 [OMICSLINK™ NEUROG2 Lentiviral ORF expression clone]
Yu, C., et al. (2023). Flot2 acts as a novel mediator of podocyte injury in proteinuric kidney disease. Int J Biol Sci doi: 10.7150/ijbs.78945 [OMICSLINK™ empty vector; GLuc-ON™ promoter reporter clone; Lenti-Pac™ HIV Expression Packing Kit; Secrete-Pair™ Dual Luminescence Assay Kit]
Yan, B., et al. (2023). The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression. Exp Mol Med doi: 10.1038/s12276-023-00997-z [OmicsLink™ Expression Clone vectors; OMICSLINK™ shRNA expression clone]
Watson, D.C., et al. (2023). GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity. Nat Cancer doi: 10.1038/s43018-023-00556-5 [OMICSLINK™ empty vector]
Lee, J.H., et al. (2023). The Piezo channel is central to the mechano-sensitive channel complex in the mammalian inner ear. Res Sq doi: 10.21203/rs.3.rs-2287052/v1 [OMICSLINK™ Pdch15, Tmie , Lfhpl5, Tmc1 and Cib2 ORF expression clone]
Li, B., et al. (2023). Cell networks in the mouse liver during partial hepatectomy. bioRxiv doi: 10.1101/2023.07.16.549116 [OMICSLINK™ Fstl1 expression clone]
Wasser, C., et al. (2023). Apoer2-ICD-dependent regulation of hippocampal ribosome mRNA loading. Res Sq doi: 10.21203/rs.3.rs-3040567/v1 [Gluc + SEAP reporter clone pEZX-GA01]
Ankenbauer, K.E., et al. (2023). Sialylation of EGFR by ST6GAL1 induces receptor activation and modulates trafficking dynamics. bioRxiv doi: 10.1101/2023.06.03.543566 [OMICSLINK™ ST6GAL1 ORF expression clone]
Sun, Y., et al. (2023). ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma. Cancer Res doi: 10.1158/0008-5472.CAN-22-3105 [OMICSLINK™ ZDHHC2 and AGK ORF expression clone]
He, B., et al. (2023). IL-13/IL-13RA2 signaling promotes colorectal cancer stem cell tumorigenesis by inducing ubiquitinated degradation of p53. Genes Dis doi: 10.1016/j.gendis.2023.01.027 [OMICSLINK™ IL-13RA2 and p53 ORF expression clone]
Naulé, L., et al. (2023). MKRN3 inhibits puberty onset via interaction with IGF2BP1 and regulation of hypothalamic plasticity. JCI Insight doi: 10.1172/jci.insight.164178 [OMICSLINK™ MKRN3 ORF expression clone]
Yuan, Z-L., et al. (2023). Inhibition of ERK downregulates autophagy via mitigating mitochondrial fragmentation to protect SH-SY5Y cells from OGD/R injury. Cell Commun Signal doi: 10.1186/s12964-023-01211-3 [OMICSLINK™ Mfn2 and Drp1 ORF expression clone]
Yang, Y-C., et al. (2023). The RNA-binding protein KSRP aggravates malignant progression of clear cell renal cell carcinoma through transcriptional inhibition and post-transcriptional destabilization of the NEDD4L ubiquitin ligase. J Biomed Sci doi: 10.1186/s12929-023-00949-9 [OMICSLINK™ NEDD4L ORF expression clone; Secrete-Pair™ Gaussia Luciferase Assay kit]
Peng, S., et al. (2023). PHF8-GLUL axis in lipid deposition and tumor growth of clear cell renal cell carcinoma. Sci Adv doi: 10.1126/sciadv.adf3566 [OMICSLINK™ TEAD1 ORF expression clone]
Song, C., et al. (2023). RA-induced prominence-specific response resulted in distinctive regulation of Wnt and osteogenesis. Life Sci Alliance doi: 10.26508/lsa.202302013 [OMICSLINK™ RARE ORF expression clone]
Hu, X., et al. (2023). Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2‐positive gastric cancer. Cancer Commun (Lond) doi: 10.1002/cac2.12459 [OMICSLINK™ CDC42 ORF expression clone]
Liu, C., et al. (2023). PHF5A regulates the expression of the DOCK5 variant to promote HNSCC progression through p38 MAPK activation. Biol Direct doi: 10.1186/s13062-023-00396-4 [OMICSLINK™ DOCK5 ORF expression clone; OMICSLINK™ mouse Phf5a ORF expression clone]
Xu, C., et al. (2023). BCKDK regulates breast cancer cell adhesion and tumor metastasis by inhibiting TRIM21 ubiquitinate talin1. Cell Death Dis doi: 10.1038/s41419-023-05944-4 [OMICSLINK™ ORF expression clone]
Fu, J., et al. (2023). The checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone disease. Nat Commun doi: 10.1038/s41467-023-39769-8 [OMICSLINK™ ORF expression clone]
Ueda, H., et al. (2023). Characterization of cytoskeletal and structural effects of INF2 variants causing glomerulopathy and neuropathy. Sci Rep doi: 10.1038/s41598-023-38588-7 [OMICSLINK™ INF2 ORF expression clone]
Li, Y., et al. (2023). The Role of STAT3 Signaling Pathway Activation in Subconjunctival Scar Formation after Glaucoma Filtration Surgery. Int J Mol Sci doi: 10.3390/ijms241512210 [OMICSLINK™ SOCS3 ORF expression clone]
Zhou, L., et al. (2023). Syntaxin-6 promotes the progression of hepatocellular carcinoma and alters its sensitivity to chemotherapies by activating the USF2/LC3B axis. Int J Biol Sci doi: 10.7150/ijbs.86636 [OMICSLINK™ STX6 ORF expression clone; OMICSLINK™ STX6 shRNA clone]
Kim, E., et al. (2023). TSG101 Physically Interacts with Linear Ubiquitin Chain Assembly Complex (LUBAC) and Upregulates the TNFα-Induced NF-κB Activation. Mol Cells doi: 10.14348/molcells.2023.0026 [OMICSLINK™ RNF31, RBCK1, SHARPIN, OTULIN, TSG101 and SPATA2 ORF expression clone]
Fan, W., et al. (2023). ZFP57 promotes ovarian cancer progression by transcriptionally regulating BRCA1 and managing G1 checkpoint. J Cancer doi: 10.7150/jca.84601 [OMICSLINK™ ZFP57 ORF expression clone]
Yan, B., et al. (2023). The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression. Exp Mol Med doi: 10.1038/s12276-023-00997-z [OMICSLINK™ YTHDC1, GLUT3, RNF183 ORF expression clone; OMICSLINK™ YTHDC1,RNF183 shRNA clone set]
Trivellin, G., et al. (2023). Germline loss-of-function PAM variants are enriched in subjects with pituitary hypersecretion. Front Endocrinol (Lausanne) doi: 10.3389/fendo.2023.1166076 [OMICSLINK™ PAM ORF expression clone]
Hua, H-S., et al. (2023). Endothelin-1 induces connective tissue growth factor expression in human lung fibroblasts by disrupting HDAC2/Sin3A/MeCP2 corepressor complex. J Biomed Sci doi: 10.1186/s12929-023-00931-5 [OMICSLINK™ HDAC2, Sin3A, MeCP2, and HDAC7 ORF expression clone]
Tu, H., et al. (2023). Loss of MEG3 contributes to the enhanced migration and invasion in arsenic-induced carcinogenesis through NQO1/FSCN1 pathway. Am J Cancer Res [OMICSLINK™ FSCN1 ORF expression clone]
Jiang, X., et al. (2023). Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice. Nat Commun doi: 10.1038/s41467-023-39256-0 [OMICSLINK™ Mouse Nat10 ORF expression clone]
Liu, X., et al. (2023). Loss of function of GATA3 regulates FRA1 and c-FOS to activate EMT and promote mammary tumorigenesis and metastasis. Cell Death Dis doi: 10.1038/s41419-023-05888-9 [OMICSLINK™ Gata3 shRNA expression clones; OMICSLINK™ FOS ORF expression clone]
Hu, H., et al. (2023). Role and mechanism of leukemia inhibitory factor receptor in cervical cancer invasion and metastasis. J Int Med Res doi: 10.1177/03000605231182557 [OMICSLINK™ LIFR ORF expression clone]
Tien, J., et al. (2023). Modifying antibody-FcRn interactions to increase the transport of antibodies through the blood-brain barrier. MAbs doi: 10.1080/19420862.2023.2229098 [OMICSLINK™ mouse Fcgrt, B2m Lentiviral ORF expression clone]
Wan, E., et al. (2023). METTL3-dependent m6A methylation facilitates uterine receptivity and female fertility via balancing estrogen and progesterone signaling. Cell Death Dis doi: 10.1038/s41419-023-05866-1 [OMICSLINK™ mouse Myc ORF expression clones; empty control vector for pReceiver-M02]
Guo, L., et al. (2023). Directed natural evolution generates a next-generation oncolytic virus with a high potency and safety profile. Nat Commun doi: 10.1038/s41467-023-39156-3 [OMICSLINK™ nsP3 Lentiviral ORF expression clone]
Watson, D.C., et al. (2023). GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity. Nat Cancer doi: 10.1038/s43018-023-00556-5 [OMICSLINK™ ORF expression clones]
Wynne, M.E., et al. (2023). APOE expression and secretion are modulated by mitochondrial dysfunction. eLife doi: 10.7554/eLife.85779 [OMICSLINK™ SLC25A1 ORF expression clone]
Yeon, M., et al. (2023). Parkin ubiquitination of Kindlin-2 enables mitochondria-associated metastasis suppression. J Biol Chem doi: 10.1016/j.jbc.2023.104774 [OMICSLINK™ ORF expression clone]
Gaol. F., et al. (2023). The analysis of cathepsin L that mediates cellular SARS‐CoV‐2 infection leading to COVID‐19 in head and neck squamous cell carcinoma. Front Immunol doi: 10.3389/fimmu.2023.1156038 [OMICSLINK™ CTSL ORF expression clone]
Khan, J.Q., et al. (2023). Generation of a SARS-CoV-2 Reverse Genetics System and Novel Human Lung Cell Lines That Exhibit High Virus-Induced Cytopathology. Viruses doi: 10.3390/v15061281 [OMICSLINK™ ACE2 ORF expression clone]
Xue, Y., et al. (2023). Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models. Proc Natl Acad Sci U S A doi: 10.1073/pnas.2217885120 [OMICSLINK™ mouse Rpe65, Lrat ORF expression clone]
Eraso, P., et al. (2023). New Functions of Intracellular LOXL2: Modulation of RNA-Binding Proteins. Molecules doi: 10.3390/molecules28114433 [OMICSLINK™ LOXL2 ORF expression clone]
Tundidor, I., et al. (2023). Identification of fatty acid amide hydrolase as a metastasis suppressor in breast cancer. Nat Commun doi: 10.1038/s41467-023-38750-9 [OMICSLINK™ FAAH ORF expression clone]
Xu, J.B., et al. (2023). Breast metastatic tumors in lung can be substituted by lung-derived malignant cells transformed by alternative splicing H19 lncRNA. Breast Cancer Res doi: 10.1186/s13058-023-01662-z [OMICSLINK™ mouse Sf3b1 ORF expression clone]
Steć, A., et al. (2023). Protein overproduction alters exosome secretion in Chinese hamster ovary cells. Anal Bioanal Chem doi: 10.1007/s00216-023-04725-4 [OMICSLINK™ BCHE ORF expression clone]
Plasterer, C., et al. (2023). NNAT is a novel mediator of oxidative stress that suppresses ER + breast cancer. Mol Med doi: 10.1186/s10020-023-00673-y [GLuc-ON™ NNAT promoter-reporter clone; OMICSLINK™ NRF1，E2F1 and E2F4 ORF expression clone]
Cao, W., et al. (2023). Knockdown of FUT11 inhibits the progression of gastric cancer via the PI3K/AKT pathway. Heliyon doi: 10.1016/j.heliyon.2023.e17600 [OMICSLINK™ FUT11 shRNA clone; OMICSLINK™ COL6A3 ORF expression clone]
He, J., et al. (2023). Astragaloside IV Attenuates High-Glucose-Induced Impairment in Diabetic Nephropathy by Increasing Klotho Expression via the NF-κB/NLRP3 Axis. J Diabetes Res doi: 10.1155/2023/7423661 [EndoFectin™ Max; OMICSLINK™ mouse Kl ORF expression clone]
Li, F., et al. (2023). RIPK1-dependent necroptosis promotes vasculogenic mimicry formation via eIF4E in triple-negative breast cancer. Cell Death Dis doi: 10.1038/s41419-023-05841-w [Lenti-Pac™ HIV Expression Packaging Kit; OMICSLINK™ RIPK1, EIF4E ORF expression clone; OMICSLINK™ RIPK1 shRNA expression clones]
Singh, S.P., et al. (2023). Human CCR6+ Th cells show both an extended stable gradient of Th17 activity and imprinted plasticity. bioRxiv doi: 10.1101/2023.01.05.522630 [Lentifect™ lentiviral particles; OMICSLINK™ Lentiviral ORF expression clone]
Li, X., et al. (2023). Beclin1- and Atg13-dependent autophagy activation and morroniside have synergistic effect on osteoblastogenesis. Exp Biol Med (Maywood) doi: 10.1177/15353702221116879 [Lenti-Pac™ HIV Expression Packaging Kit; OMICSLINK™ Lentiviral ORF expression clone]
Wei, Y., et al. (2023). LncRNA XIST promotes adjuvant-induced arthritis by increasing the expression of YY1 via miR-34a-5p. Arch Rheumatol doi: 10.46497/ArchRheumatol.2022.9250 [miExpress™ inhibitor clone; OMICSLINK™ lentiviral shRNA clone; OMICSLINK™ ORF expression clones; Lenti-Pac™ HIV Expression Packaging Kit]
Wang, X., et al. (2023). Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells. Drug Metab Dispos doi: 10.1124/dmd.121.000693 [OMICSLINK™ shRNA clone; OMICSLINK™ ORF expression clone]
Jiang, L., et al. (2023). Chaperoning of specific tau structure by immunophilin FKBP12 regulates the neuronal resilience to extracellular stress. Sci Adv doi: 10.1126/sciadv.add9789 [OMICSLINK™ NEUROG2 Lentiviral ORF expression clone]
Subramaniyan, B., et al. (2023). The Isolation and In Vitro Differentiation of Primary Fetal Baboon Tracheal Epithelial Cells for the Study of SARS-CoV-2 Host-Virus Interactions. Viruses doi: Viruses [OMICSLINK™ ACE2 lentiviral ORF expression clone; empty vector control]
Nieddu, V., et al. (2023). Matrix Gla Protein drives stemness and tumor initiation in ovarian cancer. Cell Death Dis doi: 10.1038/s41419-023-05760-w [OMICSLINK™ MGP ORF expression clone]
Wang, Y-C., et al. (2023). Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination. bioRxiv doi: 10.1101/2023.01.31.526362 [OMICSLINK™ Lentiviral ORF expression clone]
Trivellin, G., et al. (2023). Germline loss-of-function PAM variants are enriched in subjects with pituitary hypersecretion. medRxiv doi: 10.1101/2023.01.20.23284646 [OMICSLINK™ ORF expression clone]
Shatat, M.A., et al. (2023). Mistletoe lectin inhibits growth of Myc‐amplified small‐cell lung cancer. Cancer Med doi: 10.1002/cam4.5558 [OMICSLINK™ Lentiviral ORF expression clone]
Yang, Q., et al. (2023). Adipocyte-Specific Modulation of KLF14 Expression in Mice Leads to Sex-Dependent Impacts on Adiposity and Lipid Metabolism. Diabetes doi: 10.2337/db21-0674 [OMICSLINK™ ORF expression clone]
Reilly, A., et al. (2023). Lamin B1 deletion in myeloid neoplasms causes nuclear anomaly and altered hematopoietic stem cell function. Cell Stem Cell doi: Cell Stem Cell [OMICSLINK™ ORF expression clone]
Huang, B.X., et al. (2023). Interaction between GPR110 (ADGRF1) and tight junction protein occludin implicated in blood-brain barrier permeability. iScience doi: 10.1016/j.isci.2023.106550 [OMICSLINK™ GPR110-HA ORF expression clone]
Xiang, Q., et al. (2023). Neuroglobin plays as tumor suppressor by disrupting the stability of GPR35 in colorectal cancer. Clin Epigenetics doi: 10.1186/s13148-023-01472-2 [OMICSLINK™ GPR35 ORF expression clone]
Tang, Y., et al. (2023). Pan-cancer analysis and experimental validation of DTL as a potential diagnosis; prognosis and immunotherapy biomarker. BMC Cancer doi: 10.1186/s12885-023-10755-z [OMICSLINK™ DTL ORF expression clone]
Alburquerque-Bejar, J.J., et al. (2023). MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer. Cell Rep Med doi: 10.1016/j.xcrm.2023.101006 [OMICSLINK™ IFNGR1 ORF expression clone]
Soto, J.S., et al. (2023). Astrocyte–neuron subproteomes and obsessive–compulsive disorder mechanisms. Nature doi: 10.1038/s41586-023-05927-7 [OMICSLINK™ Slc1a2、Dlgap3 ORF expression clone]
Moyer, A.J., et al. (2023). Overexpression screen of chromosome 21 genes reveals modulators of Sonic hedgehog signaling relevant to Down syndrome. Dis Model Mech doi: 10.1242/dmm.049712 [OMICSLINK™ C16orf52 ORF expression clone]
Mukhopadhyay, S., et al. (2023). Autophagy supports mitochondrial metabolism through the regulation of iron homeostasis in pancreatic cancer. Sci Adv doi: 10.1126/sciadv.adf9284 [OMICSLINK™ ISCA1、EGFP ORF expression clone]
Minh, G.L., et al. (2023). Kruppel-like factor 8 regulates triple negative breast cancer stem cell-like activity. Front Oncol doi: 10.3389/fonc.2023.1141834 [OMICSLINK™ KLF8、OGT ORF expression clone]
Kim, S., et al. (2023). Rare CIDEC coding variants enriched in age-related macular degeneration patients with small low-luminance deficit cause lipid droplet and fat storage defects. PLoS One doi: 10.1371/journal.pone.0280484 [OMICSLINK™ PLIN1、RAB8A、CIDEC ORF expression clone and their rare variants]
Kaur, G., et al. (2023). Overexpression of GREM1 Improves the Survival Capacity of Aged Cardiac Mesenchymal Progenitor Cells via Upregulation of the ERK/NRF2-Associated Antioxidant Signal Pathway. Cells doi: 10.3390/cells12081203 [OMICSLINK™ GREM1 ORF expression clone]
He, Q., et al. (2023). Clonorchis sinensis granulin promotes malignant transformation of human intrahepatic biliary epithelial cells through interaction with M2 macrophages via regulation of STAT3 phosphorylation and the MEK/ERK pathway. Parasit Vectors doi: 10.1186/s13071-023-05765-6 [OMICSLINK™ CsGRN ORF expression clone]
Roganowicz, M., et al. (2023). BAZ2A-RNA mediated association with TOP2A and KDM1A represses genes implicated in prostate cancer. Life Sci Alliance doi: 10.26508/lsa.202301950 [OMICSLINK™ mouse BAZ2A ORF expression clone; OMICSLINK™ BAZ2A shRNA expression clone]
Wang, Y., et al. (2023). DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC. Nat Commun doi: 10.1038/s41467-023-38160-x [OMICSLINK™ POLD1 ORF expression clone]
Lleixà, C., et al. (2023). Antibodies against the flotillin-1/2 complex in patients with multiple sclerosis. Brain Commun doi: 10.1093/braincomms/fcad109 [OMICSLINK™ NFASC、FLOT2 ORF expression clone]
Davalos, V., et al. (2023). An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma. Nat Commun doi: 10.1038/s41467-023-36967-2 [OMICSLINK™ NR2F2 ORF expression clone]
Yang, Y., et al. (2023). PLCG2 can exist in eccDNA and contribute to the metastasis of non-small cell lung cancer by regulating mitochondrial respiration. Cell Death Dis doi: 10.1038/s41419-023-05755-7 [OMICSLINK™ PLCG2 ORF expression clone and its negative control; PLCG2-siRNA]
Zhou, R., et al. (2023). PRPF19 facilitates colorectal cancer liver metastasis through activation of the Src-YAP1 pathway via K63-linked ubiquitination of MYL9. Cell Death Dis doi: 10.1038/s41419-023-05776-2 [OMICSLINK™ PRPF19、MYL9 ORF expression clone]
An, N., et al. (2023). Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells. Oncogene doi: 10.1038/s41388-023-02612-x [OMICSLINK™ PIK3IP1 ORF expression clone and its empty vector]
Ju, H., et al. (2023). Activating transcription factor-2 supports the antioxidant capacity and ability of human mesenchymal stem cells to prevent asthmatic airway inflammation. Exp Mol Med doi: 10.1038/s12276-023-00943-z [L x R recombination clone]
Pan, Y., et al. (2023). EHBP1L1 Drives Immune Evasion in Renal Cell Carcinoma through Binding and Stabilizing JAK1. Adv Sci (Weinh) doi: 10.1002/advs.202206792 [OMICSLINK™ EHBP1L1、JAK1 ORF expression clone]
Li, Y., et al. (2023). AT7867 Inhibits the Growth of Colorectal Cancer Stem-Like Cells and Stemness by Regulating the Stem Cell Maintenance Factor Ascl2 and Akt Signaling. Stem Cells Int doi: 10.1155/2023/4199052 [OMICSLINK™ Ascl2 ORF expression clone]
Forrest, M.P., et al. (2023). Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub. Nat Commun doi: 10.1038/s41467-023-36087-x [OMICSLINK™ FLAG-Prrt2 ORF expression clone]
Chen, F., et al. (2023). Potential Role of Superoxide Dismutase 3 (SOD3) in Resistance to Influenza A Virus Infection. Antioxidants (Basel) doi: 10.3390/antiox12020354 [OMICSLINK™ SOD3 ORF expression clone]
Zeng, X., et al. (2023). Micall2 Is Responsible for the Malignancy of Clear Cell Renal Cell Carcinoma. Yonago Acta Med doi: 10.33160/yam.2023.02.021 [OMICSLINK™ Micall2 ORF expression clone]
Palicharla, V.R., et al. (2023). Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia. Mol Biol Cell doi: 10.1091/mbc.E22-10-0473 [OMICSLINK™ CYS1 ORF expression clone]
Ohlson, M.B., et al. (2023). Genome-Scale CRISPR Screening Reveals Host Factors Required for Ribosome Formation and Viral Replication. mBio doi: 10.1128/mbio.00127-23 [OMICSLINK™ SBDS ORF expression clone]
Ding, M., et al. (2023). Knocking down GALNT6 promotes pyroptosis of pancreatic ductal adenocarcinoma cells through NF-κB/NLRP3/GSDMD and GSDME signaling pathway. Front Oncol doi: 10.3389/fonc.2023.1097772 [OMICSLINK™ GALNT6 ORF expression clone]
Nasehi, R., et al. (2023). 3D geometry orchestrates the transcriptional landscape of metastatic neuroblastoma cells in a multicellular in vitro bone model. Mater Today Bio doi: 10.1016/j.mtbio.2023.100596 [OMICSLINK™ eGFP ORF expression clone]
Hasan, M.N., et al. (2023). Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice. J Lipid Res doi: 10.1016/j.jlr.2023.100340 [OMICSLINK™ Fgf15 ORF expression clone; AAVPrime™ AAV particles expressing Fgf15]
Iftikhar, R., et al. (2023). Epiploic Adipose Tissue (EPAT) in Obese Individuals Promotes Colonic Tumorigenesis: A Novel Model for EPAT-Dependent Colorectal Cancer Progression. Cancers (Basel) doi: 10.3390/cancers15030977 [OMICSLINK™ HT29 ORF expression clone]
Liu, R., et al. (2023). A Novel PDK1/MEK Dual Inhibitor Induces Cytoprotective Autophagy via the PDK1/Akt Signaling Pathway in Non-Small Cell Lung Cancer. Pharmaceuticals (Basel) doi: 10.3390/ph16020244 [OMICSLINK™ PDK1 ORF expression clone]
Chen, Y., et al. (2023). Restoration of lipid homeostasis between TG and PE by the LXRα-ATGL/EPT1 axis ameliorates hepatosteatosis. Cell Death Dis doi: 10.1038/s41419-023-05613-6 [OMICSLINK™ NR1H3 ORF expression clone; OMICSLINK™ mouse Nr1h3 ORF expression clone]
Yang, C-C., et al. (2023). Melatonin-Assisted Cisplatin Suppresses Urinary Bladder Cancer Cell Proliferation and Growth through Inhibiting PrPC-Regulated Cell Stress and Cell Proliferation Signaling. Int J Mol Sci doi: 10.3390/ijms24043353 [OMICSLINK™ PRNP ORF expression clone]
Li, Q., et al. (2023). SAMD9 Promotes Postoperative Recurrence of Esophageal Squamous Cell Carcinoma by Stimulating MYH9‐Mediated GSK3β/β‐Catenin Signaling. Adv Sci (Weinh) doi: 10.1002/advs.202203573 [OMICSLINK™ GSK3B ORF expression clone]
Luo, J., et al. (2023). Special AT‐rich sequence binding protein 1 promotes multidrug resistance in gastric cancer by regulation of Ezrin to alter subcellular localization of ATP‐binding cassette transporters. Cancer Sci doi: 10.1111/cas.15693 [OMICSLINK™ SATB1 ORF expression clone]
Zeng, K., et al. (2023). EVL Promotes Osteo-/Odontogenic Differentiation of Dental Pulp Stem Cells via Activating JNK Signaling Pathway. Stem Cells Int doi: 10.1155/2023/7585111 [OMICSLINK™ EVL ORF expression clone]
Lin, Y-W., et al. (2023). Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition. Cells doi: 10.3390/cells12030352 [OMICSLINK™ MMP2 ORF expression clone]
Yang, C., et al. (2023). TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs. Cell Death Dis doi: 10.1038/s41419-023-05577-7 [OMICSLINK™ RNF26 ORF expression clone]
Liao, M., et al. (2023). Hepatic TNFRSF12A promotes bile acid-induced hepatocyte pyroptosis through NFκB/Caspase-1/GSDMD signaling in cholestasis. Cell Death Discov doi: 10.1038/s41420-023-01326-z [OMICSLINK™ TNFRSF12A ORF expression clone]
Kim, S.E., et al. (2023). Multiple Effects of Echinochrome A on Selected Ion Channels Implicated in Skin Physiology. Mar Drugs doi: 10.3390/md21020078 [OMICSLINK™ TRPV3 ORF expression clone]
Karner, C., et al. (2023). Targeting epigenetic features in clear cell sarcomas based on patient-derived cell lines. J Transl Med doi: 10.1186/s12967-022-03843-4 [OMICSLINK™ TERT ORF expression clone]
Zudeh, G., et al. (2023). PACSIN2 as a modulator of autophagy and mercaptopurine cytotoxicity: mechanisms in lymphoid and intestinal cells. Life Sci Alliance doi: 10.26508/lsa.202201610 [OMICSLINK™ Expression-Ready ORF cDNA Vector]
LIU, C-L., et al. (2023). Aberrant Expression of Solute Carrier Family 35 Member A2 Correlates With Tumor Progression in Breast Cancer. In Vivo doi: 10.21873/invivo.13076 [OMICSLINK™ SLC35A2 ORF expression clone]
Yu, X., et al. (2023). Nanotherapy for bone repair: milk-derived small extracellular vesicles delivery of icariin. Drug Deliv doi: 10.1080/10717544.2023.2169414 [pEZX-PG04.1]
Liu, P., et al. (2023). FUT2 promotes the tumorigenicity and metastasis of colorectal cancer cells via the Wnt/β-catenin pathway. Int J Oncol doi: 10.3892/ijo.2023.5483 [vectors (pGPU6/GFP/Neo-FUT2 or pGPU6/GFP/Neo-shNC)]
Travis, A.M., et al. (2023). Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration. eLife doi: 10.7554/eLife.80533 [OMICSLINK™ NPHP3 ORF expression clone]
Diaz-Ruano, A.B., et al. (2023). Estradiol and Estrone Have Different Biological Functions to Induce NF-κB-Driven Inflammation; EMT and Stemness in ER+ Cancer Cells. Int J Mol Sci doi: 10.3390/ijms24021221 [OMICSLINK™ ORF expression clone]
Okamoto, E., et al. Regulation of Paracellular Fluxes of Amino Acids by Claudin-8 in Normal Mouse Intestinal MCE301 Cells. Nutrients doi: 10.3390/nu15061346 [OMICSLINK™ CLDN8 ORF expression clone]
Yang, Y., et al. DNA-dependent protein kinase catalytic subunit (DNA-PKcs) drives chronic kidney disease progression in male mice. Nat Commun doi: 10.1038/s41467-023-37043-5 [OMICSLINK™ SMAD2 ORF expression clone]
Turrell, F.K., et al. (2023). Age-associated microenvironmental changes highlight the role of PDGF-C in ER+ breast cancer metastatic relapse. Nat Cancer doi: 10.1038/s43018-023-00525-y [OMICSLINK™ SRPRB ORF expression clone an empty control vector]
Liu, Y., et al. (2023). PCGEM1 promotes cell proliferation and migration in endometriosis by targeting miR-124-3p-mediated ANTXR2 expression. BMC Womens Health doi: 10.1186/s12905-023-02250-1 [pGL3-ANTXR2 reporter vectors]
Phoomak, C., et al. (2023). Signal recognition particle receptor-β (SR-β) coordinates cotranslational N-glycosylation. Sci Adv doi: 10.1126/sciadv.ade8079 [OMICSLINK™ SRPRB ORF expression clone an empty control vector]
Xia, Y., et al. (2023). Silencing of STE20-type kinase TAOK1 confers protection against hepatocellular lipotoxicity through metabolic rewiring. Hepatol Commun doi: 10.1097/HC9.0000000000000037 [OMICSLINK™ TAOK1 ORF expression clone]
Pang, N., et al. (2023). Nicotinamide Adenine Dinucleotide Precursor Suppresses Hepatocellular Cancer Progression in Mice. Nutrients doi: 10.3390/nu15061447 [EX-hLUC-Lv201; Luc-Pair™ Duo-Luciferase Assay Kit 2.0]
Smaldone, G., et al. (2023). The Oncosuppressive Properties of KCTD1: Its Role in Cell Growth and Mobility. Biology (Basel) doi: 10.3390/biology12030481 [pReceiver-M94 plasmid]
Saran, C., et al. (2023). Effect of mTOR inhibitors on sodium taurocholate cotransporting polypeptide (NTCP) function in vitro. Front Pharmacol doi: 10.3389/fphar.2023.1147495 [OMICSLINK™ NTCP ORF expression clone and empty vector]
Nadler, M.J.S., et al. (2023). Hominoid SVA-lncRNA AK057321 targets human-specific SVA retrotransposons in SCN8A and CDK5RAP2 to initiate neuronal maturation. Commun Biol doi: 10.1038/s42003-023-04683-8 [OMICSLINK™ ZNF91 ORF expression clone]
Wang, N., et al. (2023). USP7- and PRMT5-dependent G3BP2 stabilization drives de novo lipogenesis and tumorigenesis of HNSC. Cell Death Dis doi: 10.1038/s41419-023-05706-2 [Wild-type G3BP2; PRMT5; truncated and R468K-mutant G3BP2 plasmids]
Xiong, H., et al. (2023). Cytotoxic CD161−CD8+ TEMRA cells contribute to the pathogenesis of systemic lupus erythematosus. eBioMedicine doi: 10.1016/j.ebiom.2023.104507 [OMICSLINK™ MYD88 ORF expression clone]
Chen, L., et al. (2023). The PI3K-Akt-mTOR pathway mediates renal pericyte-myofibroblast transition by enhancing glycolysis through HKII. J Transl Med doi: 10.1186/s12967-023-04167-7 [OMICSLINK™ Hk2 ORF expression clone; EndoFectin™ MAX]
Wang, B., et al. (2023). Exosomes From Adipose-Derived Stem Cells Suppress the Progression of Chronic Endometritis. Cell Transplant doi: 10.1177/09636897231173736 [pcDNA3.1 plasmid vector]
Zhu, X., et al. (2023). Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss. Nat Commun doi: 10.1038/s41467-023-38594-3 [Control vector for SMARCA2 and SMARCA4]
Reiter, S., et al. (2023). Development of immortalized rhesus macaque kidney cells supporting infection with a panel of viruses. PLoS One doi: 10.1371/journal.pone.0284048 [OMICSLINK™ CTSL ORF expression clone]
Mansouri, M., et al. (2023). Protein Networks Associated with Native Metabotropic Glutamate 1 Receptors (mGlu1) in the Mouse Cerebellum. Cells doi: 10.3390/cells12091325 [OMICSLINK™ mouse Glu1α ORF expression clone; OMICSLINK™ mouse KCTD12 lentiviral ORF expression clone]
Wang, Y., et al. (2023). Zinc finger and SCAN domain-containing protein 18 is a potential DNA methylation-modified tumor suppressor and biomarker in breast cancer. Front Endocrinol (Lausanne) doi: 10.3389/fendo.2023.1095604 [OMICSLINK™ ZSCAN18 ORF expression clone]

x

在线客服

技术电话

020-32068595

4006020200

微信扫码