293Ta腺相关病毒包装细胞系
GCI-AAV-293Ta包装细胞系是专门用于AAV病毒包装的工具细胞，转染效率高，能够实现病毒蛋白高水平的表达。
腺相关病毒滴度检测试剂盒
GeneCopoeia设计的AAVPrime™ AAV qPCR 腺相关病毒滴度检测试剂盒采用TaqMan探针法，可用于检测各种不同的血清型（只要你所构建的AAV载体的ITRs同样来源于AAV2），可高效、快速、准确地测定病毒拷贝数，并确定病毒包装是否成功。
AAVPrime™ AAV qPCR 腺相关病毒滴度检测试剂盒主要包括DNA酶I、AAV裂解液、TaqMan-qPCR检测试剂、探针试剂以及标准品对照。
Hasan, K.M., et al. (2023). Fatty Acid Excess Dysregulates CARF to Initiate the Development of Hepatic Steatosis. Cells doi: 10.3390/cells12071069 [AAVPrime™ AAV particles expressing CARF and AAV-empty vector; OMICSLINK™ CARF Lentiviral ORF expression clone]
Hasan, M.N., et al. (2023). Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice. J Lipid Res doi: 10.1016/j.jlr.2023.100340 [OMICSLINK™ Fgf15 ORF expression clone; AAVPrime™ AAV particles expressing Fgf15]
Gannon, A-L., et al. (2022). A Novel Model Using AAV9-Cre to Knockout Adult Leydig Cell Gene Expression Reveals a Physiological Role of Glucocorticoid Receptor Signalling in Leydig Cell Function Int J Mol Sci doi: 10.3390/ijms232315015 [AAVPrime™ AAV particles expressing CRE and GFP]
Chen, X., et al. (2022). Pitx3 deficiency promotes age-dependent alterations in striatal medium spiny neurons. Front Aging Neurosci doi: 10.3389/fnagi.2022.960479 [AAV-hSyn1-eGFP]
Hogan, T.B., et al. (2022). Caveolin-1 Peptide Regulates p53-microRNA-34a Feedback in Fibrotic Lung Fibroblasts. iScience doi: 10.1016/j.isci.2022.104022 [AAVPrime™ AAV particles expressing microRNA inhibitors]
Yang, B., et al. (2022). Evaluation of Early Biomarkers of Atherosclerosis Associated with Polychlorinated Biphenyl Exposure: An in Vitro and in Vivo Study. Environmental Health Perspectives doi: 10.1289/EHP9833 [AAVPrime™ AAV particles expressing HDAC7]
Xia, Y., et al. (2022). Neuronal C/EBPb/AEP pathway shortens life span via selective GABAnergic neuronal degeneration by FOXO repression. Science Advances doi: 10.1126/sciadv.abj8658 [AAVPrime™ AAV particles expressing FOXO1, shRNA targeting FOXO1]
Song, M-Y., et al. (2022). Sirt6 reprograms myofibers to oxidative type through CREB-dependent Sox6 suppression. Nature Communications doi: 10.1038/s41467-022-29472-5 [AAVPrime™ AAV particles expressing Sirt6, shRNA targeting Sirt6]
Lio, J., et al. (2022). C/EBPβ/AEP signaling couples atherosclerosis to the pathogenesis of Alzheimer’s disease. Molecular Psychiatry doi: 10.1038/s41380-022-01556-0 [AAVPrime™ AAV particles expressing shRNA targeting ApoE]
Toan, N.K., et al. (2021). Choline Acetyltransferase Induces the Functional Regeneration of the Salivary Gland in Aging SAMP1/Kl -/- Mice. International Journal of Molecular Sciences doi: 10.3390/ijms22010404 [AAVPrime™ AAV particles expressing shRNA targeting ChAT]
Zhang, W-B., et al. (2021). Activation of Nrf2 by miR-152 Inhibits Doxorubicin-InducedCardiotoxicity via Attenuation of Oxidative Stress, Inflammation,and Apoptosis. Oxidative Medicine and Cellular Longevity doi: 10.1155/2021/8860883 [AAVPrime™ AAV particles expressing mir-152 miRNA; AAVPrime™ AAV particles expressing shRNA targeting Nrf2]
Kang, S.S., et al. (2021). ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer’s disease. Acta Neuropathologica doi: 10.1007/s00401-021-02315-1 [AAVPrime™ AAV particles expressing ApoE4]
Quan, D.N. and Shiloach, J. (2021). rAAV production and titration at the microscale for high- throughput screening. Human Gene Therapy doi: 10.1089/hum.2021.080 [AAVPrime™ AAV particles expressing EGFP]
Han, L., et al. (2020). Homocysteine-induced electrical remodeling via the mediation of IP3R1/Nav1.5 signaling pathway. Am J Transl Res. 2020; 12(7): 3822–3841 [AAVPrime™ AAV particles expressing shRNA targeting IP3R1]
Luo, Y., et al. (2020). Upregulation of circ_0000199 in circulating exosomes is associated with survival outcome in OSCC. Scientific Reports doi: 10.1038/s41598-020-70747-y [AAVPrime™ AAV particles expressing shRNA targeting circ_0000199]
Luo, Y., et al. (2020). A novel epigenetic regulation of circFoxp1 on Foxp1 in colon cancer cells. Cell Death & Disease doi: 10.1038/s41419-020-03007-6 [AAVPrime™ AAV particles expressing shRNA targeting circ_FoxP1]
Millett, P.J., et al. (2020). Gene Editing to Impove Joint Function. United States Patent Applicaitons doi: 20200360454K [AAVPrime™ AAV particles expressing GFP]
Zhao, Y. and Ren, J. (2019). MODIFIED IMMUNE CELLS HAVING ENHANCED FUNCTION AND METHODS FOR SCREENING FOR SAME. United States Patent Application 20190345491 [AAVPrime™ AAV particles expressing DNMT3A]
