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COVID-19 ORF克隆

 

GeneCopoeia提供OmicsLink™即用型 ORF表达克隆,在表达即用型ORF cDNA克隆领域处于行业领先地位,我们也携带启动子和3' UTR microRNA (miRNA)结合位点靶点的报告质粒克隆。我们可以在250多种的载体中为SARS-CoV-2病毒蛋白和宿主蛋白提供质粒克隆。你可以从下面的列表中选择。

我们还提供其它冠状病毒(SARS-CoV、MERS-CoV)的病毒蛋白克隆。

SARS-CoV-2病毒蛋白克隆

Product ID Protein accession Symbol Alias Description
CoV201 YP_009724389.1 orf1ab GU280_gp01 orf1ab polyprotein [Severe acute respiratory syndrome coronavirus 2}, full-length gene
CoV202 YP_009725297.1 orf1ab GU280_gp01 leader protein [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV203 YP_009725298.1 orf1ab GU280_gp01 nsp2n [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV204 YP_009725299.1 orf1ab GU280_gp01 nsp3n [Severeacute respiratory syndrome coronavirus 2], mature peptide*
CoV205 YP_009725300.1 orf1ab GU280_gp01 nsp4n [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV206 YP_009725301.1 orf1ab GU280_gp01 3C-like proteinasen [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV207 YP_009725302.1 orf1ab GU280_gp01 nsp6n [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV208 YP_009725303.1 orf1ab GU280_gp01 nsp7n [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV209 YP_009725304.1 orf1ab GU280_gp01 nsp8n [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV210 YP_009725305.1 orf1ab GU280_gp01 nsp9n [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV211 YP_009725306.1 orf1ab GU280_gp01 nsp10n [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV212 YP_009725307.1 orf1ab GU280_gp01 RNA-dependent RNA polymerasen [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV213 YP_009725308.1 orf1ab GU280_gp01 helicasen [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV214 YP_009725309.1 orf1ab GU280_gp01 3'-to-5' exonucleasen [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV215 YP_009725310.1 orf1ab GU280_gp01 endoRNAsen [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV216 YP_009725311.1 orf1ab GU280_gp01 2'-O-ribose methyltransferasen [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV217 YP_009725295.1 orf1a GU280_gp01 orf1a polyproteinn [Severe acute respiratory syndrome coronavirus 2], full-length gene
CoV218 YP_009725312.1 orf1a GU280_gp01 produced by pp1a onlyn [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV219 YP_009724390.1 S GU280_gp02 surface glycoprotein;structural protein; spike proteinn [Severe acute respiratory syndrome coronavirus 2], full-length gene
CoV220 YP_009724390.1 S1 GU280_gp02 surface glycoprotein subunit 1 [Severe acute respiratory syndrome coronavirus 2], mature peptide
CoV221 YP_009724390.1 S2 GU280_gp02 surface glycoprotein subunit 2 [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV222 YP_009724390.1 RBD GU280_gp02 Receptor binding domain [Severe acute respiratory syndrome coronavirus 2], mature peptide*
CoV223 YP_009724391.1 ORF3a GU280_gp03 ORF3a protein [Severe acute respiratory syndrome coronavirus 2], full-length gene
CoV224 YP_009724392.1 E GU280_gp04 envelope protein [Severe acute respiratory syndrome coronavirus 2], full-length gene
CoV225 YP_009724393.1 M GU280_gp05 membrane glycoprotein [Severe acute respiratory syndrome coronavirus 2], full-length gene
CoV226 YP_009724394.1 ORF6 GU280_gp06 ORF6 protein [Severe acute respiratory syndrome coronavirus 2], full-length gene
CoV227 YP_009724395.1 ORF7a GU280_gp07 ORF7a protein [Severe acute respiratory syndrome coronavirus 2], full-length gene
CoV228 YP_009725318.1 ORF7b GU280_gp08 ORF7b [Severe acute respiratory syndrome coronavirus 2], full-length gene
CoV229 YP_009724396.1 ORF8 GU280_gp09 ORF8 protein [Severe acute respiratory syndrome coronavirus 2], full-length gene
CoV230 YP_009724397.2 N GU280_gp10 nucleocapsid phosphoprotein [Severe acute respiratory syndrome coronavirus 2], full-length gene
CoV231 YP_009725255.1 ORF10 GU280_gp11 ORF10 protein [Severe acute respiratory syndrome coronavirus 2], full-length gene

*注:成熟肽是前体蛋白的加工而成。为了使这些蛋白在细胞中表达,在ORF序列的5'端添加了ATG。

 

了解更多信息或下订单,请点击联系我们或拨打400-6020-200。

SARS-CoV-2病毒宿主蛋白克隆-ACE2

ACE2 ORF克隆有人和鼠的,其他可定制。

                         

 

SARS-CoV-2病毒宿主蛋白克隆-TMPRSS2

TMPRSS2 ORF克隆有人和鼠的,其他可定制。

 

SARS-CoV-2病毒宿主蛋白克隆-CypA

CypA ORF克隆有人和鼠的,其他可定制。

人亲环素A克隆

Product ID Accession Symbol Alias Description
F0323 NM_021130.4 PPIA CYPA, CYPH, HEL-S-69p Homo sapiens peptidylprolyl isomerase A (PPIA), transcript variant 1, mRNA.
T2782 NM_001300981.1 PPIA CYPA, CYPH, HEL-S-69p Homo sapiens peptidylprolyl isomerase A (PPIA), transcript variant 2, mRNA.

 

小鼠亲环素A克隆

Product ID Accession Symbol Alias Description
Mm17577 NM_008907.1 Ppia 2700098C05, Cphn, CyP-18, CypA Mus musculus peptidylprolyl isomerase A (Ppia), mRNA.

SARS-CoV-2病毒宿主蛋白克隆-FKBP1A

FKBP1A ORF克隆有人和鼠的,其他可定制。

人FKBP1A克隆

Product ID Accession Symbol Alias Description
R0062 NM_000801.4 FKBP1A FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE Homo sapiens FK506 binding protein 1A (FKBP1A), transcript variant 1, mRNA.
Z8544 NM_001199786.1 FKBP1A FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE Homo sapiens FK506 binding protein 1A (FKBP1A), transcript variant 3, mRNA.

 

小鼠FKBP1A克隆

Product ID Accession Symbol Alias Description
Mm02519 NM_008019.2 Fkbp1a 12kDa, FKBP12, FKBP12-T1, FKBP12-T2, Fkbp, Fkbp1, mFKBP1, mFKBP12 Mus musculus FK506 binding protein 1a (Fkbp1a), mRNA.
Mm38146 NM_001302078.1 Fkbp1a FKBP12, Fkbp, Fkbp1 Mus musculus FK506 binding protein 1a (Fkbp1a), transcript variant 4, mRNA.
Mm38147 NM_001302079.1 Fkbp1a FKBP12, Fkbp, Fkbp1 Mus musculus FK506 binding protein 1a (Fkbp1a), transcript variant 5, mRNA.
Mm38985 NM_001355078.1 Fkbp1a FKBP12, Fkbp, Fkbp1 Mus musculus FK506 binding protein 1a (Fkbp1a), transcript variant 8, mRNA.

 

其他SARS-CoV-2病毒宿主相关蛋白克隆

 

近期Nature杂志 (Gordon, et al., 2020) 报道,通过亲和纯化-质谱分析方法,得到了332个与26个SARS-CoV-2病毒蛋白具有相互作用的宿主基因。Gordon等认为,这些宿主基因与SARS-CoV-2病毒之间不一定是生理上相关的,比如,其中的66个宿主基因是现已知的一些抑制病毒复制的药物的潜在靶点。

Genecopoeia可为您提供这332个SARS-CoV-2病毒宿主相关蛋白克隆,您可选购单个基因或者整个文库,构建到250+种非慢病毒或慢病毒载体上。查看整个文库的产品信息,请前往ORF克隆套装