技术

抗体（Antibodies）

<2019 Mizui, T., et al. (2019). Cerebrospinal fluid BDNF pro-peptide levels in major depressive disorder and schizophrenia. Journal of Psychiatric Research doi: 10.1016/j.jpsychires.2019.03.024 [anti-human proBDNF a...

基因组编辑工具（CRISPR & TALEN）

>2020 Frendewey, D., et al. (2020). METHODS AND COMPOSITIONS FOR TARGETED GENETIC MODIFICATION USING PAIRED GUIDE RNAS. United States Patent Application 20200002730 [GeneHero™ sgRNA clones targeting Lrp5] Zh...

荧光标记和检测技术（Fluorescent Labeling and Detection）

>2020 Luo, Q., et al. (2020). TRIM32/USP11 Balances ARID1A Stability and the Oncogenic/Tumor-Suppressive Status of Squamous Cell Carcinoma. Cell Reports doi: 10.1016/j.celrep.2019.12.017 [TUNEL Andy Fluor...

预制稳转株（Stable cell lines）

<2021 Hashizume, M., et al. (2021). Population-Specific ACE2 Single-Nucleotide Polymorphisms Have Limited Impact on SARS-CoV-2 Infectivity In Vitro. Viruses doi: 10.3390/v13010067 [ACE2-expressing HEK293T stable cel...

转染试剂（Transfection reagents）

>2021 Gurung, C., et al. (2021). Dicer represses the interferon response and the double-stranded RNA-activated protein kinase pathway in mouse embryonic stem cells. The Journal of Biological Chemistry doi: 10.1016/j...

荧光素酶检测（Luciferase Assays）

>2021 Lv, X., et al. (2021). Negative Feedback Loop Between NAMPT and TGF-β Signaling Pathway in Colorectal Cancer Cells. Oncotargets and Therapy doi: 10.2147/OTT.S282367 [Luc‐Pair™ Duo‐Lucifer...

重组蛋白

<2016 Zhou, Y., et al. (2016) Competitive profiling of celastrol targets in human cervical cancer HeLa cells via quantitative chemical proteomics . Molecular Biosystems 10.1039/C6MB00691D [Recombinant human GSTO1 pr...

启动子报告克隆（Promoter Reporter Clones）

<2021 Wu, D., et al. (2020). Long non-coding RNA GClnc1 knockdown suppresses progression of epithelial ovarian cancer by recruiting FOXC2 to disrupt the NOTCH1/NF-κB/Snail pathway. Experimental Cell Research d...

qPCR Arrays

Huang, L. et al. (2012) Downregulation of Six MicroRNAs Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix. PLoS ONE 7(3): e33762. doi:10.1371/journal.pone.0033762....

分子生物学试剂

< 2016 Bid, HK., et al. (2016). The Bromodomain BET inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of Childhood Sarcoma. Molecular Cancer Therapeutics,Published ...

基因下调—shRNA

<2021 Mao, Y., et al. (2021). Aberrantly up-regulated miR-142-3p inhibited the proliferation and invasion of trophoblast cells by regulating FOXM1. Placenta doi: 10.1016/j.placenta.2021.01.002 [OMICSLINK™ FOXM...

miRNA解决方案

<2021 Duan, J., et a. (2021). miR-152/TNS1 axis inhibits non-small cell lung cancer progression through Akt/mTOR/RhoA pathway. Bioscience Reports doi: 10.1042/BSR20201539 [All-in-One™ miRNA miRNA extraction ki...

GeneCopoeia miRNA 全面解决方案 — 全面广泛的功能分析和检测工具帮您彻底了解miRNA（检测和定量细胞中的miRNA）

研究miRNA的作用，或验证假设的目标miRNA，GeneCopoeia提供正确的解决方法。GeneCopoeia miRNA 研究工具帮助您设计有效实验回答您的疑问。某个特异miRNA的调节功能是怎样实现的? miRNA表达量的变化会直接或间接导致癌症或其他疾病吗? 如...

Gateway克隆技术原理

Gateway克隆技术基于已研究的非常清楚的λ噬菌体位点特异重组系统，使用Int (integrase)和 IHF (Integration Host Factor) 催化重组反应， attB和attP位点的重组反应会生成attL和attR...

Gateway® Technology

Gateway®克隆技术的基础是 λ噬菌体的位点特异性重组反应，一种保存遗传信息的有效的生化途径（见图1）。与传统的需要DNA限制性内切酶、DNA连接酶、凝胶电泳和DNA片段纯化等多个步骤的繁琐亚克隆方法相比，该方法只需一步生化反...

OmicsLink™ 克隆的应用及与全长转录本cDNA克隆的区别

可以在E.coli 细胞中表达蛋白可以通过反向转染在哺乳动物细胞中表达蛋白可以在体外无细胞体系中表达蛋白表达带有标签的蛋白，可用于纯化和下游分析产生原位杂...

qPCR验证引物与试剂盒

构建目的表达克隆的高效方法

ORFEXPRESS™-Shuttle Clone与目的载体attL和attR位点的重组反应可以生成目的表达克隆。这种特异性极高的重组反应不会导致LXR位点间碱基的增加或删除。在 ORFEXPRESS™-Shuttle Clone中，起始...

慢病毒产品与服务

<2021 Joshi, S., et al. (2021). ACE2 Gene Transfer Ameliorates Vasoreparative Dysfunction in CD34+ Cells Derived from Diabetic Older Adults. Clinical Science doi: 10.1042/CS20201133 [Lentifect™ Lentiviral part...

ORF/cDNA克隆

<2021 Xiang, H., et al. (2021). miR-124-3p combined with miR-506-3p delay hepatic carcinogenesis via modulating sirtuin. Biomarkers doi: 10.1080/1354750X.2020.1854856 [OMICSLINK™ ...