简介
细胞因子（CK）是由免疫原、有丝分裂原或其他刺激物在多种细胞中诱导的低分子量可溶性蛋白（5～20kDa），一般通过与细胞表面相应的细胞因子受体结合，通过信号转导，引起细胞基因转录的变化。细胞因子具有调节固有免疫和适应性免疫、血细胞生成、细胞生长、APSC多能细胞以及损伤组织修复等多种功能。根据细胞因子主要的功能不同可分为：白细胞介素（IL）、集落刺激因子（CSF）、干扰素（IFN）、肿瘤坏死因子（TNF）、转化生长因子-β家族（TGF-β family）、生长因子（GF）和趋化因子家族（chemokine family）。 大多数细胞因子受体（CK-R）是由两个或两个以上的亚单位组成的异源二聚体或多聚体，通常包括一个特异性配体结合α链和一个参与信号的β链。在自然状态下，细胞因子受体（CK-R）主要以膜结合细胞因子受体（mCK-R）和存在于血清等体液中可溶性细胞因子受体（sCK-R）两种形式存在。细胞因子复杂的生物学活性主要是通过与相应的mCK-R结合后所介导的，而sCK-R却具有独特的生物学意义。sCK-R水平变化与某些疾病的关系日益受到学者们的重视，部分重组sCK-R基因工程产品已进入临床验证。
套装信息
| 新货号 | 旧货号 | 物种 | 基因数 | 载体 | 载体类型 | 价格 |
|---|---|---|---|---|---|---|
| OC-GF001-M02 | OC-HCC-M02 | Human | 423 | pReceiver-M02 | Expression-ready Non-viral | Inquire |
| OC-GF001-M35 | OC-HCC-M35 | Human | 423 | pReceiver-M35 | Expression-ready Non-viral | Inquire |
| OC-GF001-M98 | OC-HCC-M98 | Human | 423 | pReceiver-M98 | Expression-ready Non-viral | Inquire |
| OC-GF001-Lv105 | OC-HCC-Lv105 | Human | 423 | pReceiver-Lv105 | Expression-ready Lentiviral | Inquire |
| OC-GF001-Lv242 | OC-HCC-Lv242 | Human | 423 | pReceiver-Lv242 | Expression-ready Lentiviral | Inquire |
| OC-GF001-GC | OC-HCC-GC | Human | 423 | pDONR™ Vector | Gateway shuttle | Inquire |
克隆列表
表格仅包含克隆套装部分内容，如需更多信息请通过电话（4006-020-200）或邮件（sales@igenebio.com）联系我们。
| Symbol | NCBI注册号 | 物种 | 基因描述 | ORF length(bp) | 产品ID |
| IFNA1 | NM_024013.3 | Human | Homo sapiens interferon alpha 1 (IFNA1), mRNA. | 570 | GC-A0001 |
| PTN | NM_002825.7 | Human | Homo sapiens pleiotrophin (PTN), transcript variant 1, mRNA. | 507 | GC-A0004 |
| IL10 | NM_000572.3 | Human | Homo sapiens interleukin 10 (IL10), transcript variant 1, mRNA. | 537 | GC-A0007 |
| KITLG | NM_000899.5 | Human | Homo sapiens KIT ligand (KITLG), transcript variant b, mRNA. | 822 | GC-A0012 |
| BMP5 | NM_021073.4 | Human | Homo sapiens bone morphogenetic protein 5 (BMP5), transcript variant 1, mRNA. | 1365 | GC-A0015 |
| BMP6 | NM_001718.6 | Human | Homo sapiens bone morphogenetic protein 6 (BMP6), mRNA. | 1542 | GC-A0016 |
| FGF7 | NM_002009.4 | Human | Homo sapiens fibroblast growth factor 7 (FGF7), mRNA. | 585 | GC-A0017 |
| IL12B | NM_002187.3 | Human | Homo sapiens interleukin 12B (IL12B), mRNA. | 987 | GC-A0033 |
| IL12A | NM_000882.4 | Human | Homo sapiens interleukin 12A (IL12A), transcript variant 1, mRNA. | 762 | GC-A0034 |
| TGFB2 | NM_001135599.4 | Human | Homo sapiens transforming growth factor beta 2 (TGFB2), transcript variant 1, mRNA. | 1329 | GC-A0107 |
| AREG | NM_001657.4 | Human | Homo sapiens amphiregulin (AREG), mRNA. | 759 | GC-A0114 |
| IFNA14 | NM_002172.3 | Human | Homo sapiens interferon alpha 14 (IFNA14), mRNA. | 570 | GC-A0136 |
| IFNB1 | NM_002176.4 | Human | Homo sapiens interferon beta 1 (IFNB1), mRNA. | 564 | GC-A0137 |
| IGF1 | NM_000618.5 | Human | Homo sapiens insulin like growth factor 1 (IGF1), transcript variant 4, mRNA. | 462 | GC-A0153 |
| FGF3 | NM_005247.4 | Human | Homo sapiens fibroblast growth factor 3 (FGF3), mRNA. | 720 | GC-A0154 |
| IL11 | NM_000641.4 | Human | Homo sapiens interleukin 11 (IL11), transcript variant 1, mRNA. | 600 | GC-A0158 |
| IFNW1 | NM_002177.3 | Human | Homo sapiens interferon omega 1 (IFNW1), mRNA. | 588 | GC-A0159 |
| IL5 | NM_000879.3 | Human | Homo sapiens interleukin 5 (IL5), mRNA. | 405 | GC-A0169 |
| LTB | NM_002341.2 | Human | Homo sapiens lymphotoxin beta (LTB), transcript variant 1, mRNA. | 735 | GC-A0170 |
| IL4 | NM_000589.4 | Human | Homo sapiens interleukin 4 (IL4), transcript variant 1, mRNA. | 462 | GC-A0173 |
| CCL1 | NM_002981.2 | Human | Homo sapiens C-C motif chemokine ligand 1 (CCL1), mRNA. | 291 | GC-A0176 |
| IFNG | NM_000619.3 | Human | Homo sapiens interferon gamma (IFNG), mRNA. | 501 | GC-A0177 |
| CSF3 | NM_172219.3 | Human | Homo sapiens colony stimulating factor 3 (CSF3), transcript variant 2, mRNA. | 615 | GC-A0178 |
| IL1A | NM_000575.5 | Human | Homo sapiens interleukin 1 alpha (IL1A), transcript variant 1, mRNA. | 816 | GC-A0179 |
| IL1B | NM_000576.3 | Human | Homo sapiens interleukin 1 beta (IL1B), mRNA. | 810 | GC-A0180 |
| INHBA | NM_002192.4 | Human | Homo sapiens inhibin subunit beta A (INHBA), mRNA. | 1281 | GC-A0186 |
| BMP2 | NM_001200.4 | Human | Homo sapiens bone morphogenetic protein 2 (BMP2), mRNA. | 1191 | GC-A0241 |
| BMP4 | NM_001347916.1 | Human | Homo sapiens bone morphogenetic protein 4 (BMP4), transcript variant 8, mRNA. | 1227 | GC-A0242 |
| CXCL2 | NM_002089.4 | Human | Homo sapiens C-X-C motif chemokine ligand 2 (CXCL2), mRNA. | 324 | GC-A0267 |
| TNF | NM_000594.4 | Human | Homo sapiens tumor necrosis factor (TNF), mRNA. | 702 | GC-A0276 |
| PDGFA | NM_002607.6 | Human | Homo sapiens platelet derived growth factor subunit A (PDGFA), transcript variant 1, mRNA. | 636 | GC-A0278 |
| IL6 | NM_000600.5 | Human | Homo sapiens interleukin 6 (IL6), transcript variant 1, mRNA. | 639 | GC-A0301 |
| BMP7 | NM_001719.3 | Human | Homo sapiens bone morphogenetic protein 7 (BMP7), mRNA. | 1296 | GC-A0309 |
| IL1RN | NM_173842.3 | Human | Homo sapiens interleukin 1 receptor antagonist (IL1RN), transcript variant 1, mRNA. | 534 | GC-A0332 |
| TGFA | NM_001099691.3 | Human | Homo sapiens transforming growth factor alpha (TGFA), transcript variant 2, mRNA. | 480 | GC-A0352 |
| CXCL9 | NM_002416.3 | Human | Homo sapiens C-X-C motif chemokine ligand 9 (CXCL9), mRNA. | 378 | GC-A0353 |
| FGF4 | NM_002007.4 | Human | Homo sapiens fibroblast growth factor 4 (FGF4), mRNA. | 621 | GC-A0368 |
| PDGFB | NM_002608.4 | Human | Homo sapiens platelet derived growth factor subunit B (PDGFB), transcript variant 1, mRNA. | 726 | GC-A0380 |
| BMP1 | NM_001199.4 | Human | Homo sapiens bone morphogenetic protein 1 (BMP1), transcript variant 1, mRNA. | 2193 | GC-A0384 |
| IL2 | NM_000586.4 | Human | Homo sapiens interleukin 2 (IL2), mRNA. | 462 | GC-A0413 |
| IFNA17 | NM_021268.2 | Human | Homo sapiens interferon alpha 17 (IFNA17), mRNA. | 570 | GC-A0454 |
| CXCL12 | NM_000609.7 | Human | Homo sapiens C-X-C motif chemokine ligand 12 (CXCL12), transcript variant 2, mRNA. | 282 | GC-A0590 |
| FGF8 | NM_006119.6 | Human | Homo sapiens fibroblast growth factor 8 (FGF8), transcript variant B, mRNA. | 648 | GC-A0640 |
| NGF | NM_002506.3 | Human | Homo sapiens nerve growth factor (NGF), mRNA. | 726 | GC-A0708 |
| IL7 | NM_000880.4 | Human | Homo sapiens interleukin 7 (IL7), transcript variant 1, mRNA. | 534 | GC-A0790 |
| MDK | NM_002391.6 | Human | Homo sapiens midkine (MDK), transcript variant 3, mRNA. | 432 | GC-A0792 |
| IFNA2 | NM_000605.4 | Human | Homo sapiens interferon alpha 2 (IFNA2), mRNA. | 567 | GC-A0813 |
| HGF | NM_000601.6 | Human | Homo sapiens hepatocyte growth factor (HGF), transcript variant 1, mRNA. | 2187 | GC-A0820 |
| FGF1 | NM_001257209.1 | Human | Homo sapiens fibroblast growth factor 1 (FGF1), transcript variant 11, mRNA. | 468 | GC-A0853 |
| IL17A | NM_002190.3 | Human | Homo sapiens interleukin 17A (IL17A), mRNA. | 468 | GC-A0895 |
