简介
离子通道（Ion channnels）是细胞膜（包括细胞质膜和细胞内膜）上具有特殊功能的跨膜蛋白质，由于带电的离子不能自由通过磷脂双分子层，只能通过细胞膜上的离子通道进行转运。离子通道存在于所有细胞的膜中，其分布及活性对细胞、组织的兴奋性及功能十分重要，人体组织中存在多种离子通道，每种通道又存在多种亚型，如钙离子通道包括KCTD10、KCNMA1、KCNIP2、SCN5A和CHRNA3等成员，钾离子通道包括TASK-1、TASK-3、TREK-1、MthK等成员，每个成员的核酸序列特异。它们既是生理调节的重要因素，又可作为药物作用的靶点研制新的特异性药物。
套装信息
| 新货号 | 旧货号 | 物种 | 基因数 | 载体 | 载体类型 | 价格 |
|---|---|---|---|---|---|---|
| OC-GF010-M02 | OC-HIC-M02 | Human | 448 | pReceiver-M02 | Expression-ready Non-viral | Inquire |
| OC-GF010-M35 | OC-HIC-M35 | Human | 448 | pReceiver-M35 | Expression-ready Non-viral | Inquire |
| OC-GF010-M98 | OC-HIC-M98 | Human | 448 | pReceiver-M98 | Expression-ready Non-viral | Inquire |
| OC-GF010-Lv105 | OC-HIC-Lv105 | Human | 448 | pReceiver-Lv105 | Expression-ready Lentiviral | Inquire |
| OC-GF010-Lv242 | OC-HIC-Lv242 | Human | 448 | pReceiver-Lv242 | Expression-ready Lentiviral | Inquire |
| OC-GF010-GC | OC-HIC-GC | Human | 448 | pDONR™ Vector | Gateway shuttle | Inquire |
克隆列表
表格仅包含克隆套装部分内容，如需更多信息请通过电话（4006-020-200）或邮件（sales@igenebio.com）联系我们。
| Symbol | NCBI注册号 | 物种 | 基因描述 | ORF length(bp) | 产品ID |
| GABRB3 | NM_000814.6 | Human | Homo sapiens gamma-aminobutyric acid type A receptor subunit beta3 (GABRB3), transcript variant 1, mRNA. | 1422 | GC-A0053 |
| CHRNA5 | NM_000745.4 | Human | Homo sapiens cholinergic receptor nicotinic alpha 5 subunit (CHRNA5), transcript variant 1, mRNA. | 1407 | GC-A0055 |
| KCNA5 | NM_002234.4 | Human | Homo sapiens potassium voltage-gated channel subfamily A member 5 (KCNA5), mRNA. | 1842 | GC-A0121 |
| GABRA1 | NM_001127643.2 | Human | Homo sapiens gamma-aminobutyric acid type A receptor subunit alpha1 (GABRA1), transcript variant 2, mRNA. | 1371 | GC-A0140 |
| ANXA7 | NM_001156.5 | Human | Homo sapiens annexin A7 (ANXA7), transcript variant 1, mRNA. | 1401 | GC-A0189 |
| KCNA2 | NM_004974.4 | Human | Homo sapiens potassium voltage-gated channel subfamily A member 2 (KCNA2), transcript variant 1, mRNA. | 1500 | GC-A0194 |
| CACNG1 | NM_000727.4 | Human | Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 1 (CACNG1), mRNA. | 669 | GC-A0209 |
| GABRA5 | NM_000810.4 | Human | Homo sapiens gamma-aminobutyric acid type A receptor subunit alpha5 (GABRA5), transcript variant 1, mRNA. | 1389 | GC-A0216 |
| SCN1B | NM_001037.5 | Human | Homo sapiens sodium voltage-gated channel beta subunit 1 (SCN1B), transcript variant a, mRNA. | 657 | GC-A0221 |
| GRIN1 | NM_007327.4 | Human | Homo sapiens glutamate ionotropic receptor NMDA type subunit 1 (GRIN1), transcript variant GluN1-1a, mRNA. | 2817 | GC-A0292 |
| VDAC1 | NM_003374.3 | Human | Homo sapiens voltage dependent anion channel 1 (VDAC1), transcript variant 1, mRNA. | 852 | GC-A0299 |
| KCNA6 | NM_002235.5 | Human | Homo sapiens potassium voltage-gated channel subfamily A member 6 (KCNA6), transcript variant 4, mRNA. | 1590 | GC-A0329 |
| GABRG2 | NM_000816.3 | Human | Homo sapiens gamma-aminobutyric acid type A receptor gamma2 subunit (GABRG2), transcript variant 2, mRNA. | 1404 | GC-A0402 |
| CHRM2 | NM_001006630.2 | Human | Homo sapiens cholinergic receptor muscarinic 2 (CHRM2), transcript variant 1, mRNA. | 1401 | GC-A0448 |
| GLRA2 | NM_001118885.2 | Human | Homo sapiens glycine receptor alpha 2 (GLRA2), transcript variant 2, mRNA. | 1359 | GC-A0526 |
| CHRND | NM_000751.3 | Human | Homo sapiens cholinergic receptor nicotinic delta subunit (CHRND), transcript variant 1, mRNA. | 1554 | GC-A0532 |
| GRIK2 | NM_021956.5 | Human | Homo sapiens glutamate ionotropic receptor kainate type subunit 2 (GRIK2), transcript variant 1, mRNA. | 2727 | GC-A0588 |
| CNGB1 | NM_001135639.2 | Human | Homo sapiens cyclic nucleotide gated channel subunit beta 1 (CNGB1), transcript variant 2, mRNA. | 900 | GC-A0599 |
| KCNJ2 | NM_000891.3 | Human | Homo sapiens potassium inwardly rectifying channel subfamily J member 2 (KCNJ2), mRNA. | 1284 | GC-A0609 |
| KCNJ6 | NM_002240.5 | Human | Homo sapiens potassium inwardly rectifying channel subfamily J member 6 (KCNJ6), mRNA. | 1272 | GC-A0611 |
| GABRA4 | NM_000809.4 | Human | Homo sapiens gamma-aminobutyric acid type A receptor subunit alpha4 (GABRA4), transcript variant 1, mRNA. | 1665 | GC-A0620 |
| GLRB | NM_001166060.1 | Human | Homo sapiens glycine receptor beta (GLRB), transcript variant 2, mRNA. | 1494 | GC-A0627 |
| KCNAB2 | NM_001199861.2 | Human | Homo sapiens potassium voltage-gated channel subfamily A regulatory beta subunit 2 (KCNAB2), transcript variant 4, mRNA. | 1104 | GC-A0628 |
| KCNK1 | NM_002245.4 | Human | Homo sapiens potassium two pore domain channel subfamily K member 1 (KCNK1), mRNA. | 1011 | GC-A0629 |
| CHRNB2 | NM_000748.3 | Human | Homo sapiens cholinergic receptor nicotinic beta 2 subunit (CHRNB2), mRNA. | 1509 | GC-A0648 |
| CLCN2 | NM_004366.6 | Human | Homo sapiens chloride voltage-gated channel 2 (CLCN2), transcript variant 1, mRNA. | 2697 | GC-A0687 |
| CHRNA4 | NM_000744.7 | Human | Homo sapiens cholinergic receptor nicotinic alpha 4 subunit (CHRNA4), transcript variant 1, mRNA. | 1884 | GC-A0724 |
| SCNN1G | NM_001039.4 | Human | Homo sapiens sodium channel epithelial 1 subunit gamma (SCNN1G), mRNA. | 1950 | GC-A0726 |
| AQP4 | NM_004028.5 | Human | Homo sapiens aquaporin 4 (AQP4), transcript variant 2, mRNA. | 906 | GC-A0762 |
| CACNB3 | NM_000725.4 | Human | Homo sapiens calcium voltage-gated channel auxiliary subunit beta 3 (CACNB3), transcript variant 1, mRNA. | 1455 | GC-A0872 |
| GRIK1 | NM_000830.6 | Human | Homo sapiens glutamate ionotropic receptor kainate type subunit 1 (GRIK1), transcript variant 1, mRNA. | 2757 | GC-A0927 |
| GABRB2 | NM_000813.3 | Human | Homo sapiens gamma-aminobutyric acid type A receptor subunit beta2 (GABRB2), transcript variant 2, mRNA. | 1425 | GC-A0939 |
| CHRNA7 | NM_000746.6 | Human | Homo sapiens cholinergic receptor nicotinic alpha 7 subunit (CHRNA7), transcript variant 1, mRNA. | 1509 | GC-A0962 |
| KCNH2 | NM_000238.4 | Human | Homo sapiens potassium voltage-gated channel subfamily H member 2 (KCNH2), transcript variant 1, mRNA. | 3480 | GC-A1128 |
| KCNJ4 | NM_004981.2 | Human | Homo sapiens potassium inwardly rectifying channel subfamily J member 4 (KCNJ4), transcript variant 2, mRNA. | 1338 | GC-A1149 |
| GABRA6 | NM_000811.3 | Human | Homo sapiens gamma-aminobutyric acid type A receptor subunit alpha6 (GABRA6), mRNA. | 1362 | GC-A1235 |
| CHRM1 | NM_000738.3 | Human | Homo sapiens cholinergic receptor muscarinic 1 (CHRM1), mRNA. | 1383 | GC-A1293 |
| ATP4B | NM_000705.4 | Human | Homo sapiens ATPase H+/K+ transporting subunit beta (ATP4B), mRNA. | 876 | GC-C0018 |
| ATP1A2 | NM_000702.4 | Human | Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. | 3063 | GC-C0098 |
| ATP2B4 | NM_001684.5 | Human | Homo sapiens ATPase plasma membrane Ca2+ transporting 4 (ATP2B4), transcript variant 2, mRNA. | 3618 | GC-C0208 |
| ATP1B1 | NM_001677.4 | Human | Homo sapiens ATPase Na+/K+ transporting subunit beta 1 (ATP1B1), mRNA. | 912 | GC-C0229 |
| AQP2 | NM_000486.5 | Human | Homo sapiens aquaporin 2 (AQP2), mRNA. | 816 | GC-C0649 |
| CLCN3 | NM_001829.4 | Human | Homo sapiens chloride voltage-gated channel 3 (CLCN3), transcript variant b, mRNA. | 2457 | GC-E0037 |
| GABRA2 | NM_001114175.3 | Human | Homo sapiens gamma-aminobutyric acid type A receptor subunit alpha2 (GABRA2), transcript variant 2, mRNA. | 1356 | GC-E0263 |
| GABRB2 | NM_021911.3 | Human | Homo sapiens gamma-aminobutyric acid type A receptor subunit beta2 (GABRB2), transcript variant 1, mRNA. | 1539 | GC-E0533 |
| CACNA2D3 | NM_018398.2 | Human | Homo sapiens calcium voltage-gated channel auxiliary subunit alpha2delta 3 (CACNA2D3), mRNA. | 3276 | GC-E0680 |
| SCN4B | NM_174934.4 | Human | Homo sapiens sodium voltage-gated channel beta subunit 4 (SCN4B), transcript variant 1, mRNA. | 687 | GC-E0734 |
| ATP2A1 | NM_004320.6 | Human | Homo sapiens ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 (ATP2A1), transcript variant a, mRNA. | 2985 | GC-E1171 |
| TPCN1 | NM_017901.6 | Human | Homo sapiens two pore segment channel 1 (TPCN1), transcript variant 2, mRNA. | 2451 | GC-E1339 |
| KCNK18 | NM_181840.1 | Human | Homo sapiens potassium two pore domain channel subfamily K member 18 (KCNK18), mRNA. | 1155 | GC-E1355 |
