简介
磷酸酶（Phosphatases）具有与蛋白激酶相反的功能，通过将磷酸单酯水解成一个磷酸基团和一个带有游离羟基的分子来去除磷酸化的蛋白质中的磷酸基团。去磷酸化作用同样主要发生在丝氨酸、苏氨酸和酪氨酸残基上。磷蛋白磷酸酶（phosphoprotein phosphatases，PPPs）家族成员包括PP1、PP2A、PP2B、PP4、PP5、PP6和PP7蛋白，它们的催化亚基多与各种的调节亚基相结合。而以PP2C蛋白为代表的金属依赖型蛋白磷酸酶（metal-dependent protein phosphatases，PPMs）家族成员不具有调节亚基，并且催化过程依赖于金属离子如 Mn2+或Mg2+。蛋白质磷酸化的异常与多种类疾病的发生存在关联性，从癌症到炎症性疾病、糖尿病、传染病、心血管疾病等。
套装信息
| 新货号 | 旧货号 | 物种 | 基因数 | 载体 | 载体类型 | 价格 |
|---|---|---|---|---|---|---|
| OC-GF016-M02 | OC-HPH-M02 | Human | 288 | pReceiver-M02 | Expression-ready Non-viral | Inquire |
| OC-GF016-M35 | OC-HPH-M35 | Human | 288 | pReceiver-M35 | Expression-ready Non-viral | Inquire |
| OC-GF016-M98 | OC-HPH-M98 | Human | 288 | pReceiver-M98 | Expression-ready Non-viral | Inquire |
| OC-GF016-Lv105 | OC-HPH-Lv105 | Human | 288 | pReceiver-Lv105 | Expression-ready Lentiviral | Inquire |
| OC-GF016-Lv242 | OC-HPH-Lv242 | Human | 288 | pReceiver-Lv242 | Expression-ready Lentiviral | Inquire |
| OC-GF016-GC | OC-HPH-GC | Human | 288 | pDONR™ Vector | Gateway shuttle | Inquire |
克隆列表
表格仅包含克隆套装部分内容，如需更多信息请通过电话（4006-020-200）或邮件（sales@igenebio.com）联系我们。
| Symbol | NCBI注册号 | 物种 | 基因描述 | ORF length(bp) | 产品ID |
| PTPN3 | NM_002829.4 | Human | Homo sapiens protein tyrosine phosphatase non-receptor type 3 (PTPN3), transcript variant 1, mRNA. | 2742 | GC-A0027 |
| PTPN1 | NM_002827.4 | Human | Homo sapiens protein tyrosine phosphatase non-receptor type 1 (PTPN1), transcript variant 1, mRNA. | 1308 | GC-A0118 |
| PTPN4 | NM_002830.4 | Human | Homo sapiens protein tyrosine phosphatase non-receptor type 4 (PTPN4), mRNA. | 2781 | GC-A0131 |
| PTPRE | NM_001316677.2 | Human | Homo sapiens protein tyrosine phosphatase receptor type E (PTPRE), transcript variant 4, mRNA. | 2103 | GC-A0148 |
| DUSP1 | NM_004417.4 | Human | Homo sapiens dual specificity phosphatase 1 (DUSP1), mRNA. | 1104 | GC-A0168 |
| DUSP2 | NM_004418.4 | Human | Homo sapiens dual specificity phosphatase 2 (DUSP2), mRNA. | 945 | GC-A0223 |
| PPP3R1 | NM_000945.4 | Human | Homo sapiens protein phosphatase 3 regulatory subunit B, alpha (PPP3R1), mRNA. | 513 | GC-A0250 |
| PTPRA | NM_002836.4 | Human | Homo sapiens protein tyrosine phosphatase receptor type A (PTPRA), transcript variant 1, mRNA. | 2409 | GC-A0263 |
| PTPN6 | NM_080548.4 | Human | Homo sapiens protein tyrosine phosphatase, non-receptor type 6 (PTPN6), transcript variant 2, mRNA. | 1794 | GC-A0343 |
| PTPN11 | NM_002834.5 | Human | Homo sapiens protein tyrosine phosphatase non-receptor type 11 (PTPN11), transcript variant 1, mRNA. | 1782 | GC-A0360 |
| PPP2R5B | NM_006244.4 | Human | Homo sapiens protein phosphatase 2 regulatory subunit B'beta (PPP2R5B), mRNA. | 1494 | GC-A0565 |
| DUSP4 | NM_001394.7 | Human | Homo sapiens dual specificity phosphatase 4 (DUSP4), transcript variant 1, mRNA. | 1185 | GC-A0606 |
| PTPN2 | NM_002828.4 | Human | Homo sapiens protein tyrosine phosphatase non-receptor type 2 (PTPN2), transcript variant 1, mRNA. | 1248 | GC-A0848 |
| CDKN3 | NM_005192.4 | Human | Homo sapiens cyclin dependent kinase inhibitor 3 (CDKN3), transcript variant 1, mRNA. | 639 | GC-A0936 |
| ACP1 | NM_004300.4 | Human | Homo sapiens acid phosphatase 1 (ACP1), transcript variant 3, mRNA. | 477 | GC-C0027 |
| DUSP3 | NM_004090.4 | Human | Homo sapiens dual specificity phosphatase 3 (DUSP3), mRNA. | 558 | GC-C0127 |
| IMPA1 | NM_005536.4 | Human | Homo sapiens inositol monophosphatase 1 (IMPA1), transcript variant 1, mRNA. | 834 | GC-C0226 |
| ACP5 | NM_001611.5 | Human | Homo sapiens acid phosphatase 5, tartrate resistant (ACP5), transcript variant 4, mRNA. | 978 | GC-C0236 |
| PPP4C | NM_002720.3 | Human | Homo sapiens protein phosphatase 4 catalytic subunit (PPP4C), transcript variant 2, mRNA. | 924 | GC-C0256 |
| PPP1CA | NM_002708.4 | Human | Homo sapiens protein phosphatase 1 catalytic subunit alpha (PPP1CA), transcript variant 1, mRNA. | 993 | GC-C0257 |
| INPP1 | NM_002194.4 | Human | Homo sapiens inositol polyphosphate-1-phosphatase (INPP1), transcript variant 2, mRNA. | 1200 | GC-C0293 |
| PPP2CA | NM_002715.4 | Human | Homo sapiens protein phosphatase 2 catalytic subunit alpha (PPP2CA), transcript variant 1, mRNA. | 930 | GC-C0306 |
| PPP2CB | NM_001009552.2 | Human | Homo sapiens protein phosphatase 2 catalytic subunit beta (PPP2CB), mRNA. | 930 | GC-C0307 |
| PPP2R2A | NM_002717.4 | Human | Homo sapiens protein phosphatase 2 regulatory subunit Balpha (PPP2R2A), transcript variant 1, mRNA. | 1344 | GC-C0310 |
| PPM1A | NM_021003.5 | Human | Homo sapiens protein phosphatase, Mg2+/Mn2+ dependent 1A (PPM1A), transcript variant 1, mRNA. | 1149 | GC-C0402 |
| PFKFB1 | NM_002625.4 | Human | Homo sapiens 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1), transcript variant 1, mRNA. | 1416 | GC-C0406 |
| PPP2R5D | NM_006245.4 | Human | Homo sapiens protein phosphatase 2 regulatory subunit B'delta (PPP2R5D), transcript variant 1, mRNA. | 1809 | GC-C0421 |
| PPP1CC | NM_002710.4 | Human | Homo sapiens protein phosphatase 1 catalytic subunit gamma (PPP1CC), transcript variant 1, mRNA. | 972 | GC-C0453 |
| PPP1CB | NM_002709.3 | Human | Homo sapiens protein phosphatase 1 catalytic subunit beta (PPP1CB), transcript variant 1, mRNA. | 984 | GC-C0647 |
| PFKFB3 | NM_004566.4 | Human | Homo sapiens 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3), transcript variant 1, mRNA. | 1563 | GC-C0726 |
| ALPL | NM_000478.5 | Human | Homo sapiens alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant 1, mRNA. | 1575 | GC-C0757 |
| PFKFB2 | NM_001018053.2 | Human | Homo sapiens 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (PFKFB2), transcript variant 2, mRNA. | 1416 | GC-E0022 |
| PPM1L | NM_001317912.2 | Human | Homo sapiens protein phosphatase, Mg2+/Mn2+ dependent 1L (PPM1L), transcript variant 3, mRNA. | 546 | GC-E0380 |
| PHOSPHO1 | NM_178500.4 | Human | Homo sapiens phosphoethanolamine/phosphocholine phosphatase 1 (PHOSPHO1), transcript variant 2, mRNA. | 804 | GC-E0408 |
| PPTC7 | NM_139283.2 | Human | Homo sapiens protein phosphatase targeting COQ7 (PPTC7), transcript variant 1, mRNA. | 915 | GC-E0672 |
| HACD2 | NM_198402.5 | Human | Homo sapiens 3-hydroxyacyl-CoA dehydratase 2 (HACD2), transcript variant 2, mRNA. | 765 | GC-E1003 |
| NUDT14 | NM_177533.5 | Human | Homo sapiens nudix hydrolase 14 (NUDT14), transcript variant 1, mRNA. | 669 | GC-E1103 |
| PPM1L | NM_001317911.2 | Human | Homo sapiens protein phosphatase, Mg2+/Mn2+ dependent 1L (PPM1L), transcript variant 2, mRNA. | 702 | GC-E2053 |
| PPM1F | NM_014634.4 | Human | Homo sapiens protein phosphatase, Mg2+/Mn2+ dependent 1F (PPM1F), mRNA. | 1365 | GC-G0282 |
| PTPRCAP | NM_005608.3 | Human | Homo sapiens protein tyrosine phosphatase receptor type C associated protein (PTPRCAP), mRNA. | 621 | GC-G0799 |
| DUSP14 | NM_007026.4 | Human | Homo sapiens dual specificity phosphatase 14 (DUSP14), mRNA. | 597 | GC-I0123 |
| PTP4A3 | NM_032611.3 | Human | Homo sapiens protein tyrosine phosphatase 4A3 (PTP4A3), transcript variant 1, mRNA. | 522 | GC-I0136 |
| PTEN | NM_000314.8 | Human | Homo sapiens phosphatase and tensin homolog (PTEN), transcript variant 1, mRNA. | 1212 | GC-I0450 |
| PPM1B | NM_002706.6 | Human | Homo sapiens protein phosphatase, Mg2+/Mn2+ dependent 1B (PPM1B), transcript variant 1, mRNA. | 1440 | GC-I0466 |
| PTP4A2 | NM_080391.4 | Human | Homo sapiens protein tyrosine phosphatase 4A2 (PTP4A2), transcript variant 1, mRNA. | 504 | GC-I0503 |
| ACYP2 | NM_138448.4 | Human | Homo sapiens acylphosphatase 2 (ACYP2), transcript variant 3, mRNA. | 300 | GC-I0547 |
| PHPT1 | NM_014172.6 | Human | Homo sapiens phosphohistidine phosphatase 1 (PHPT1), transcript variant 3, mRNA. | 378 | GC-J0134 |
| DAPP1 | NM_014395.3 | Human | Homo sapiens dual adaptor of phosphotyrosine and 3-phosphoinositides 1 (DAPP1), transcript variant 1, mRNA. | 843 | GC-L0180 |
| PPP2R5E | NM_001282179.3 | Human | Homo sapiens protein phosphatase 2 regulatory subunit B'epsilon (PPP2R5E), transcript variant 2, mRNA. | 1404 | GC-M0207 |
| PPM1G | NM_177983.3 | Human | Homo sapiens protein phosphatase, Mg2+/Mn2+ dependent 1G (PPM1G), mRNA. | 1641 | GC-M0225 |
