简介
转录因子（Transcription factors）也称为反式作用因子，是指能够结合在某基因上游特异核苷酸序列上的蛋白质，这些蛋白质能调控其基因的转录，包括TFIIA、TFIIB、TFIID、HSF、HIF、SREBP等。从蛋白质结构分析，这些转录因子一般由DNA结合域（DNA-binding Domain）、转录调控域（Transcription Regulation Domain，包括激活域或抑制域）、寡聚化位点（Oligomerization Site），以及核定位信号（Nuclear Location Signal，NLS）等4个功能区域组成。转录因子不仅与多种人类重大疾病相关，如：p53、myc、ER、Id与癌症相关；PPAR与肥胖相关；MEF2、HIF1与心脏疾病相关；而且在植物生长发育和逆境防御反应等过程中也具有重要调控作用。对转录因子及其相互作用因子的功能研究对了解它们在信号级联反应中的作用至关重要，为基础研究及生产应用提供理论依据。
套装信息
| 新货号 | 旧货号 | 物种 | 基因数 | 载体 | 载体类型 | 价格 |
|---|---|---|---|---|---|---|
| OC-GF020-M02 | OC-HTF-M02 | Human | 2412 | pReceiver-M02 | Expression-ready Non-viral | Inquire |
| OC-GF020-M35 | OC-HTF-M35 | Human | 2412 | pReceiver-M35 | Expression-ready Non-viral | Inquire |
| OC-GF020-M98 | OC-HTF-M98 | Human | 2412 | pReceiver-M98 | Expression-ready Non-viral | Inquire |
| OC-GF020-Lv105 | OC-HTF-Lv105 | Human | 2412 | pReceiver-Lv105 | Expression-ready Lentiviral | Inquire |
| OC-GF020-Lv242 | OC-HTF-Lv242 | Human | 2412 | pReceiver-Lv242 | Expression-ready Lentiviral | Inquire |
| OC-GF020-GC | OC-HTF-GC | Human | 2412 | pDONR™ Vector | Gateway shuttle | Inquire |
克隆列表
表格仅包含克隆套装部分内容，如需更多信息请通过电话（4006-020-200）或邮件（sales@igenebio.com）联系我们。
| Symbol | NCBI注册号 | 物种 | 基因描述 | ORF length(bp) | 产品ID |
| VDR | NM_001017535.2 | Human | Homo sapiens vitamin D receptor (VDR), transcript variant 2, mRNA. | 1284 | GC-A0043 |
| ESR1 | NM_000125.3 | Human | Homo sapiens estrogen receptor 1 (ESR1), transcript variant 1, mRNA. | 1788 | GC-A0322 |
| RXRB | NM_021976.5 | Human | Homo sapiens retinoid X receptor beta (RXRB), transcript variant 2, mRNA. | 1602 | GC-A0346 |
| AHR | NM_001621.5 | Human | Homo sapiens aryl hydrocarbon receptor (AHR), mRNA. | 2547 | GC-A0474 |
| RXRA | NM_002957.6 | Human | Homo sapiens retinoid X receptor alpha (RXRA), transcript variant 1, mRNA. | 1389 | GC-A0529 |
| NR0B1 | NM_000475.5 | Human | Homo sapiens nuclear receptor subfamily 0 group B member 1 (NR0B1), mRNA. | 1413 | GC-A0573 |
| NR1D1 | NM_021724.5 | Human | Homo sapiens nuclear receptor subfamily 1 group D member 1 (NR1D1), mRNA. | 1845 | GC-A0803 |
| THRA | NM_001190919.2 | Human | Homo sapiens thyroid hormone receptor alpha (THRA), transcript variant 4, mRNA. | 1473 | GC-A0835 |
| NR3C1 | NM_001024094.2 | Human | Homo sapiens nuclear receptor subfamily 3 group C member 1 (NR3C1), transcript variant 7, mRNA. | 2337 | GC-A0857 |
| NR1I3 | NM_005122.5 | Human | Homo sapiens nuclear receptor subfamily 1 group I member 3 (NR1I3), transcript variant 3, mRNA. | 1047 | GC-A0964 |
| NR2F1 | NM_005654.6 | Human | Homo sapiens nuclear receptor subfamily 2 group F member 1 (NR2F1), mRNA. | 1272 | GC-A1000 |
| NR1H3 | NM_005693.4 | Human | Homo sapiens nuclear receptor subfamily 1 group H member 3 (NR1H3), transcript variant 1, mRNA. | 1344 | GC-A1306 |
| MYBL2 | NM_002466.4 | Human | Homo sapiens MYB proto-oncogene like 2 (MYBL2), transcript variant 1, mRNA. | 2103 | GC-B0073 |
| HMGB2 | NM_001130688.1 | Human | Homo sapiens high mobility group box 2 (HMGB2), transcript variant 2, mRNA. | 630 | GC-B0079 |
| RUNX1 | NM_001122607.2 | Human | Homo sapiens RUNX family transcription factor 1 (RUNX1), transcript variant 3, mRNA. | 753 | GC-B0083 |
| TP53 | NM_000546.6 | Human | Homo sapiens tumor protein p53 (TP53), transcript variant 1, mRNA. | 1182 | GC-B0105 |
| ELK1 | NM_005229.4 | Human | Homo sapiens ELK1, ETS transcription factor (ELK1), transcript variant 2, mRNA. | 1287 | GC-B0214 |
| SMAD4 | NM_005359.6 | Human | Homo sapiens SMAD family member 4 (SMAD4), mRNA. | 1659 | GC-B0219 |
| FOS | NM_005252.4 | Human | Homo sapiens Fos proto-oncogene, AP-1 transcription factor subunit (FOS), mRNA. | 1143 | GC-B0247 |
| RUNX3 | NM_004350.3 | Human | Homo sapiens RUNX family transcription factor 3 (RUNX3), transcript variant 2, mRNA. | 1248 | GC-B0301 |
| NME2 | NM_001018139.2 | Human | Homo sapiens NME/NM23 nucleoside diphosphate kinase 2 (NME2), transcript variant 4, mRNA. | 459 | GC-C0166 |
| NR2F2 | NM_021005.4 | Human | Homo sapiens nuclear receptor subfamily 2 group F member 2 (NR2F2), transcript variant 1, mRNA. | 1245 | GC-C0221 |
| ARNT | NM_001668.4 | Human | Homo sapiens aryl hydrocarbon receptor nuclear translocator (ARNT), transcript variant 1, mRNA. | 2370 | GC-C0312 |
| HDAC9 | NM_014707.4 | Human | Homo sapiens histone deacetylase 9 (HDAC9), transcript variant 3, mRNA. | 1773 | GC-E0013 |
| GTF2I | NM_001518.5 | Human | Homo sapiens general transcription factor IIi (GTF2I), transcript variant 4, mRNA. | 2874 | GC-E0033 |
| RFX4 | NM_032491.6 | Human | Homo sapiens regulatory factor X4 (RFX4), transcript variant 1, mRNA. | 1926 | GC-E0092 |
| ZNF232 | NM_001320954.2 | Human | Homo sapiens zinc finger protein 232 (ZNF232), transcript variant 4, mRNA. | 1254 | GC-E0203 |
| ESRRG | NM_001438.4 | Human | Homo sapiens estrogen related receptor gamma (ESRRG), transcript variant 1, mRNA. | 1377 | GC-E0424 |
| MYOCD | NM_153604.4 | Human | Homo sapiens myocardin (MYOCD), transcript variant 2, mRNA. | 2817 | GC-E0450 |
| GSC | NM_173849.3 | Human | Homo sapiens goosecoid homeobox (GSC), mRNA. | 774 | GC-E0453 |
| GATAD2B | NM_020699.4 | Human | Homo sapiens GATA zinc finger domain containing 2B (GATAD2B), mRNA. | 1782 | GC-E0581 |
| ZNF41 | NM_001324140.2 | Human | Homo sapiens zinc finger protein 41 (ZNF41), transcript variant 4, mRNA. | 2340 | GC-E0596 |
| FOXL1 | NM_005250.3 | Human | Homo sapiens forkhead box L1 (FOXL1), mRNA. | 1038 | GC-E0843 |
| TP63 | NM_003722.5 | Human | Homo sapiens tumor protein p63 (TP63), transcript variant 1, mRNA. | 2043 | GC-E0955 |
| HOXC12 | NM_173860.3 | Human | Homo sapiens homeobox C12 (HOXC12), mRNA. | 849 | GC-E0972 |
| CREM | NM_182769.3 | Human | Homo sapiens cAMP responsive element modulator (CREM), transcript variant 13, mRNA. | 738 | GC-E1258 |
| TCF7 | NM_003202.5 | Human | Homo sapiens transcription factor 7 (TCF7), transcript variant 1, mRNA. | 1155 | GC-E1346 |
| TCF20 | NM_005650.4 | Human | Homo sapiens transcription factor 20 (TCF20), transcript variant 1, mRNA. | 5883 | GC-E1417 |
| MTUS1 | NM_020749.5 | Human | Homo sapiens microtubule associated scaffold protein 1 (MTUS1), transcript variant 5, mRNA. | 1311 | GC-E1441 |
| TRERF1 | NM_033502.4 | Human | Homo sapiens transcriptional regulating factor 1 (TRERF1), transcript variant 2, mRNA. | 3603 | GC-E1475 |
| HOXC6 | NM_004503.4 | Human | Homo sapiens homeobox C6 (HOXC6), transcript variant 1, mRNA. | 708 | GC-E1530 |
| SOX5 | NM_152989.5 | Human | Homo sapiens SRY-box transcription factor 5 (SOX5), transcript variant 2, mRNA. | 2253 | GC-E1597 |
| TBX22 | NM_016954.2 | Human | Homo sapiens T-box 22 (TBX22), transcript variant 2, mRNA. | 1563 | GC-E1621 |
| ZNF26 | NM_019591.4 | Human | Homo sapiens zinc finger protein 26 (ZNF26), transcript variant 2, mRNA. | 1602 | GC-E1630 |
| ZNF398 | NM_170686.3 | Human | Homo sapiens zinc finger protein 398 (ZNF398), transcript variant 1, mRNA. | 1929 | GC-E1852 |
| SOX5 | NM_001261414.3 | Human | Homo sapiens SRY-box transcription factor 5 (SOX5), transcript variant 4, mRNA. | 1929 | GC-E1940 |
| HSF1 | NM_005526.4 | Human | Homo sapiens heat shock transcription factor 1 (HSF1), mRNA. | 1590 | GC-F0013 |
| GATA2 | NM_001145661.2 | Human | Homo sapiens GATA binding protein 2 (GATA2), transcript variant 1, mRNA. | 1443 | GC-F0016 |
| YY1 | NM_003403.5 | Human | Homo sapiens YY1 transcription factor (YY1), mRNA. | 1245 | GC-F0023 |
| ELK4 | NM_021795.3 | Human | Homo sapiens ETS transcription factor ELK4 (ELK4), transcript variant b, mRNA. | 1218 | GC-F0031 |
