复能易锦提供的全部人类和小鼠ORF克隆及相关慢病毒和AAV病毒,所提供的载体质粒均采用毛细管电泳sanger全长测序验证,并承诺编码的氨基酸序列与NCBI数据库匹配。 All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by iGeneBio are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.
miProfile cancer miRNA qPCR arrays可对癌症密切相关的miRNA进行表达量差异分析。这些miRNA的选择均基于对权威文献的深入挖掘和仔细挑选,可用于所有癌症相关或特定癌症相关miRNA的表达量差异分析。
众所周知,miRNAs密切参与到癌症的发生和发展过程中,他们的表达模式的变化会对细胞周期和生存程序产生影响。研究者可使用miProfile cancer arrays分析正常组织和各种癌症中癌症相关miRNA的不同表达量,从而掌握这些miRNA在癌症发病机理中扮演的角色,以鉴定或证实癌症分类、诊断和预测的标记。
Lazăr, A.D., et al. (2023). Comparative Expression Profiling Reveals Molecular Markers Involved in the Progression of Cutaneous Melanoma towards Metastasis. Int J Mol Sci doi: 10.3390/ijms24076565 [ExProfile™ Cancer Gene qPCR Arrays; miProfile™ Human Cancer miRNA qPCR array; All-in-One™ qPCR Mix]
Ren, J., et al. (2021). CtIP suppresses primary microRNA maturation and promotes metastasis of colon cancer cells in a xenograft mouse model. The Journal of Biological Chemistry doi: 10.1016/j.jbc.2021.100707 [miProfile™ Human Cancer miRNA qPCR array]
Chen, K-b., et al. (2021). miR-526b-3p inhibits lung cancer cisplatin-resistance and metastasis by inhibiting STAT3-promoted PD-L1. Cell Death & Disease doi: 10.1038/s41419-021-04033-8 [miProfile™ Human Cancer miRNA qPCR array]
Boudhraa, Z., et al. (2021). NR1D1 regulation by Ran GTPase via miR4472 identifies an essential vulnerability linked to aneuploidy in ovarian cancer. Oncogene doi: 10.1038/s41388-021-02082-z [miProfile™ custom miRNA qPCR array]
Jiang, Z.T., et al. (2020). Tripterine Restrains the Aggressiveness of Hepatocellular Carcinoma Cell via Regulating miRNA-532-5p/CXCL2 Axis. Oncotargets and Therapy doi: 10.2147/OTT.S238074 [miProfile™ human cancer miRNA qPCR array]
Chen, D., et al. (2020). MiRNA‐200c‐3p promotes endothelial to mesenchymal transition and neointimal hyperplasia in artery bypass grafts. The Journal of Pathology doi: 10.1002/path.5574 [miProfile™ miRNA qPCR array]
Dong, H., et al. (2016). Reciprocal androgen receptor/interleukin‐6 crosstalk drives oesophageal carcinoma progression and contributes to patient prognosis. The Journal of Pathology doi: 10.1002/path.4839 [ExProfile™ Human Inflammatory Response and Autoimmunity Related Gene qPCR Array]
Huang, L. et al. (2012) Downregulation of Six MicroRNAs Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix. PLoS ONE 7(3): e33762.