简介
表观遗传学（Epigenetics）研究不涉及DNA序列改变的可遗传基因功能变化。这种变化最常涉及影响基因表达调节的变化，包括DNA甲基化、组蛋白修饰、染色体重塑、非编码RNA调控、基因沉默、核仁显性、休眠转座子激活和性别相关性基因剂量补偿效应等。表观遗传调控在发育、衰老、免疫调节等生理过程，以及肿瘤、神经系统疾病、代谢性疾病等多种疾病的发生发展中发挥重要作用。例如，表观遗传对神经发育相关关键基因的调控是决定胚胎干细胞向神经细胞分化的重要调控机制。
套装信息
| 新货号 | 旧货号 | 物种 | 基因数 | 载体 | 载体类型 | 价格 |
|---|---|---|---|---|---|---|
| OC-GF005-M02 | OC-HEP-M02 | Human | 656 | pReceiver-M02 | Expression-ready Non-viral | Inquire |
| OC-GF005-M35 | OC-HEP-M35 | Human | 656 | pReceiver-M35 | Expression-ready Non-viral | Inquire |
| OC-GF005-M98 | OC-HEP-M98 | Human | 656 | pReceiver-M98 | Expression-ready Non-viral | Inquire |
| OC-GF005-Lv105 | OC-HEP-Lv105 | Human | 656 | pReceiver-Lv105 | Expression-ready Lentiviral | Inquire |
| OC-GF005-Lv242 | OC-HEP-Lv242 | Human | 656 | pReceiver-Lv242 | Expression-ready Lentiviral | Inquire |
| OC-GF005-GC | OC-HEP-GC | Human | 656 | pDONR™ Vector | Gateway shuttle | Inquire |
克隆列表
表格仅包含克隆套装部分内容，如需更多信息请通过电话（4006-020-200）或邮件（sales@igenebio.com）联系我们。
| Symbol | NCBI注册号 | 物种 | 基因描述 | ORF length(bp) | 产品ID |
| CDK2 | NM_001798.5 | Human | Homo sapiens cyclin dependent kinase 2 (CDK2), transcript variant 1, mRNA. | 897 | GC-A0035 |
| VDR | NM_001017535.2 | Human | Homo sapiens vitamin D receptor (VDR), transcript variant 2, mRNA. | 1284 | GC-A0043 |
| PRKCD | NM_006254.4 | Human | Homo sapiens protein kinase C delta (PRKCD), transcript variant 1, mRNA. | 2031 | GC-A0211 |
| ERBB4 | NM_005235.3 | Human | Homo sapiens erb-b2 receptor tyrosine kinase 4 (ERBB4), transcript variant JM-a/CVT-1, mRNA. | 3927 | GC-A0212 |
| YWHAB | NM_139323.4 | Human | Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta (YWHAB), transcript variant 2, mRNA. | 741 | GC-A0340 |
| CDK5 | NM_004935.4 | Human | Homo sapiens cyclin dependent kinase 5 (CDK5), transcript variant 1, mRNA. | 879 | GC-A0348 |
| CDK7 | NM_001799.4 | Human | Homo sapiens cyclin dependent kinase 7 (CDK7), transcript variant 1, mRNA. | 1041 | GC-A0843 |
| MAPKAPK3 | NM_001243925.2 | Human | Homo sapiens MAPK activated protein kinase 3 (MAPKAPK3), transcript variant 2, mRNA. | 1149 | GC-A0888 |
| LBR | NM_002296.4 | Human | Homo sapiens lamin B receptor (LBR), transcript variant 1, mRNA. | 1848 | GC-A0933 |
| CUL2 | NM_001198778.2 | Human | Homo sapiens cullin 2 (CUL2), transcript variant 1, mRNA. | 2295 | GC-A1355 |
| PRKCB | NM_212535.3 | Human | Homo sapiens protein kinase C beta (PRKCB), transcript variant 1, mRNA. | 2016 | GC-A1601 |
| PRMT1 | NM_001207042.3 | Human | Homo sapiens protein arginine methyltransferase 1 (PRMT1), transcript variant 4, mRNA. | 858 | GC-A1680 |
| PAK2 | NM_002577.4 | Human | Homo sapiens p21 (RAC1) activated kinase 2 (PAK2), mRNA. | 1575 | GC-A1683 |
| TAF6 | NM_001190415.2 | Human | Homo sapiens TATA-box binding protein associated factor 6 (TAF6), transcript variant 5, mRNA. | 2145 | GC-A1699 |
| SMARCD1 | NM_003076.5 | Human | Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 (SMARCD1), transcript variant 1, mRNA. | 1548 | GC-A1760 |
| PRKAG1 | NM_001206710.2 | Human | Homo sapiens protein kinase AMP-activated non-catalytic subunit gamma 1 (PRKAG1), transcript variant 4, mRNA. | 900 | GC-A2011 |
| TP53 | NM_001276760.3 | Human | Homo sapiens tumor protein p53 (TP53), transcript variant 1, mRNA. | 1065 | GC-A2030 |
| AURKB | NM_001313951.1 | Human | Homo sapiens aurora kinase B (AURKB), transcript variant 5, mRNA. | 912 | GC-A2150 |
| CUL2 | NM_003591.4 | Human | Homo sapiens cullin 2 (CUL2), transcript variant 3, mRNA. | 2238 | GC-A2162 |
| DNMT3B | NM_001207055.2 | Human | Homo sapiens DNA methyltransferase 3 beta (DNMT3B), transcript variant 7, mRNA. | 2187 | GC-A2214 |
| DNMT3B | NM_001207056.2 | Human | Homo sapiens DNA methyltransferase 3 beta (DNMT3B), transcript variant 8, mRNA. | 2085 | GC-A2215 |
| CHEK1 | NM_001244846.1 | Human | Homo sapiens checkpoint kinase 1 (CHEK1), transcript variant 4, mRNA. | 1329 | GC-A2388 |
| ATF2 | NM_001256091.2 | Human | Homo sapiens activating transcription factor 2 (ATF2), transcript variant 3, mRNA. | 1464 | GC-A2490 |
| ATF2 | NM_001256094.2 | Human | Homo sapiens activating transcription factor 2 (ATF2), transcript variant 6, mRNA. | 630 | GC-A2492 |
| APBB1 | NM_001257320.2 | Human | Homo sapiens amyloid beta precursor protein binding family B member 1 (APBB1), transcript variant 6, mRNA. | 1356 | GC-A2619 |
| SUPT3H | NM_001261823.2 | Human | Homo sapiens SPT3 homolog, SAGA and STAGA complex component (SUPT3H), transcript variant 3, mRNA. | 498 | GC-A2725 |
| JARID2 | NM_001267040.1 | Human | Homo sapiens jumonji and AT-rich interaction domain containing 2 (JARID2), transcript variant 2, mRNA. | 3225 | GC-A2742 |
| EZH2 | NM_001203247.2 | Human | Homo sapiens enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2), transcript variant 3, mRNA. | 2241 | GC-A2944 |
| MTA1 | NM_004689.3 | Human | Homo sapiens metastasis associated 1 (MTA1), transcript variant 1, mRNA. | 2148 | GC-A2952 |
| MAX | NM_145113.3 | Human | Homo sapiens MYC associated factor X (MAX), transcript variant 3, mRNA. | 312 | GC-A2960 |
| CENPC | NM_001812.4 | Human | Homo sapiens centromere protein C (CENPC), transcript variant 1, mRNA. | 2832 | GC-A3021 |
| TP53 | NM_001276697.3 | Human | Homo sapiens tumor protein p53 (TP53), transcript variant 5, mRNA. | 705 | GC-A3114 |
| TOP2B | NM_001068.3 | Human | Homo sapiens topoisomerase (DNA) II beta (TOP2B), transcript variant 2, mRNA. | 4866 | GC-A3120 |
| AURKB | NM_001313950.2 | Human | Homo sapiens aurora kinase B (AURKB), transcript variant 4, mRNA. | 1035 | GC-A3181 |
| HIRIP3 | NM_003609.5 | Human | Homo sapiens HIRA interacting protein 3 (HIRIP3), transcript variant 1, mRNA. | 1671 | GC-A3187 |
| REST | NM_005612.5 | Human | Homo sapiens RE1 silencing transcription factor (REST), transcript variant 1, mRNA. | 3294 | GC-A3251 |
| NPAS2 | NM_002518.4 | Human | Homo sapiens neuronal PAS domain protein 2 (NPAS2), mRNA. | 2475 | GC-A3302 |
| BRPF1 | NM_004634.3 | Human | Homo sapiens bromodomain and PHD finger containing 1 (BRPF1), transcript variant 2, mRNA. | 3645 | GC-A3584 |
| KDM6A | NM_021140.4 | Human | Homo sapiens lysine demethylase 6A (KDM6A), transcript variant 3, mRNA. | 4206 | GC-A3666 |
| SMARCB1 | NM_003073.5 | Human | Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 (SMARCB1), transcript variant 1, mRNA. | 1158 | GC-A3765 |
| RBBP5 | NM_005057.4 | Human | Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 1, mRNA. | 1617 | GC-A3799 |
| APOBEC1 | NM_001644.5 | Human | Homo sapiens apolipoprotein B mRNA editing enzyme catalytic subunit 1 (APOBEC1), transcript variant 1, mRNA. | 711 | GC-A4151 |
| CUL1 | NM_003592.3 | Human | Homo sapiens cullin 1 (CUL1), transcript variant 1, mRNA. | 2331 | GC-A4270 |
| PRKAB1 | NM_006253.5 | Human | Homo sapiens protein kinase AMP-activated non-catalytic subunit beta 1 (PRKAB1), mRNA. | 813 | GC-A4283 |
| E2F6 | NM_212540.3 | Human | Homo sapiens E2F transcription factor 6 (E2F6), transcript variant f, mRNA. | 390 | GC-A4388 |
| ERCC6 | NM_001346440.2 | Human | Homo sapiens ERCC excision repair 6, chromatin remodeling factor (ERCC6), transcript variant 4, mRNA. | 4482 | GC-A4394 |
| CDC6 | NM_001254.4 | Human | Homo sapiens cell division cycle 6 (CDC6), mRNA. | 1683 | GC-A4506 |
| E2F6 | NM_001278277.2 | Human | Homo sapiens E2F transcription factor 6 (E2F6), transcript variant d, mRNA. | 621 | GC-A4578 |
| DPF3 | NM_001280542.3 | Human | Homo sapiens double PHD fingers 3 (DPF3), transcript variant 2, mRNA. | 1137 | GC-A4747 |
| UBE2A | NM_001282161.2 | Human | Homo sapiens ubiquitin conjugating enzyme E2 A (UBE2A), transcript variant 4, mRNA. | 360 | GC-A4851 |
