简介
药物靶标是指体内具有药效功能并能被药物作用的生物大分子，如某些蛋白质和核酸等生物大分子。那些编码靶标蛋白的基因也被称为靶标基因，事先确定靶向特定疾病有关的靶标分子是现代新药开发的基础。例如在肿瘤免疫治疗中较为经典的T细胞免疫检查点CTLA4，是由CTLA-4基因编码的一种跨膜蛋白质，表达于活化的CD4+和CD8+ T细胞，另外还有淋巴细胞激活基因3（LAG-3）和T细胞免疫球蛋白黏蛋白3（TIM-3）等。
套装信息
| 货号 | 物种 | 基因数 | 载体 | 载体类型 | 价格 |
|---|---|---|---|---|---|
| OC-HDG-M02 | Human | 8611 | pReceiver-M02 | Expression-ready Non-viral | Inquire |
| OC-HDG-M35 | Human | 8611 | pReceiver-M35 | Expression-ready Non-viral | Inquire |
| OC-HDG-M98 | Human | 8611 | pReceiver-M98 | Expression-ready Non-viral | Inquire |
| OC-HDG-Lv105 | Human | 8611 | pReceiver-Lv105 | Expression-ready Lentiviral | Inquire |
| OC-HDG-Lv242 | Human | 8611 | pReceiver-Lv242 | Expression-ready Lentiviral | Inquire |
| OC-HDG-GC | Human | 8611 | pDONR™ Vector | Gateway shuttle | Inquire |
克隆列表
表格仅包含克隆套装部分内容，如需更多信息请通过电话（4006-020-200）或邮件（sales@igenebio.com）联系我们。
| Symbol | NCBI注册号 | 物种 | 基因描述 | ORF length(bp) | 产品ID |
| IFNA1 | NM_024013.3 | Human | Homo sapiens interferon alpha 1 (IFNA1), mRNA. | 570 | GC-A0001 |
| PTN | NM_002825.7 | Human | Homo sapiens pleiotrophin (PTN), transcript variant 1, mRNA. | 507 | GC-A0004 |
| IL10 | NM_000572.3 | Human | Homo sapiens interleukin 10 (IL10), transcript variant 1, mRNA. | 537 | GC-A0007 |
| ITGA3 | NM_002204.4 | Human | Homo sapiens integrin subunit alpha 3 (ITGA3), mRNA. | 3156 | GC-A0010 |
| KITLG | NM_000899.5 | Human | Homo sapiens KIT ligand (KITLG), transcript variant b, mRNA. | 822 | GC-A0012 |
| HBEGF | NM_001945.3 | Human | Homo sapiens heparin binding EGF like growth factor (HBEGF), mRNA. | 627 | GC-A0014 |
| BMP5 | NM_021073.4 | Human | Homo sapiens bone morphogenetic protein 5 (BMP5), transcript variant 1, mRNA. | 1365 | GC-A0015 |
| BMP6 | NM_001718.6 | Human | Homo sapiens bone morphogenetic protein 6 (BMP6), mRNA. | 1542 | GC-A0016 |
| FGF7 | NM_002009.4 | Human | Homo sapiens fibroblast growth factor 7 (FGF7), mRNA. | 585 | GC-A0017 |
| AKT1 | NM_005163.2 | Human | Homo sapiens AKT serine/threonine kinase 1 (AKT1), transcript variant 1, mRNA. | 1443 | GC-A0022 |
| PTPN3 | NM_002829.4 | Human | Homo sapiens protein tyrosine phosphatase non-receptor type 3 (PTPN3), transcript variant 1, mRNA. | 2742 | GC-A0027 |
| IL12B | NM_002187.3 | Human | Homo sapiens interleukin 12B (IL12B), mRNA. | 987 | GC-A0033 |
| IL12A | NM_000882.4 | Human | Homo sapiens interleukin 12A (IL12A), transcript variant 1, mRNA. | 762 | GC-A0034 |
| CDK2 | NM_001798.5 | Human | Homo sapiens cyclin dependent kinase 2 (CDK2), transcript variant 1, mRNA. | 897 | GC-A0035 |
| MAOB | NM_000898.5 | Human | Homo sapiens monoamine oxidase B (MAOB), mRNA. | 1563 | GC-A0038 |
| CNTFR | NM_001842.5 | Human | Homo sapiens ciliary neurotrophic factor receptor (CNTFR), transcript variant 2, mRNA. | 1119 | GC-A0039 |
| ITGB8 | NM_002214.3 | Human | Homo sapiens integrin subunit beta 8 (ITGB8), mRNA. | 2310 | GC-A0040 |
| TACR1 | NM_001058.4 | Human | Homo sapiens tachykinin receptor 1 (TACR1), transcript variant long, mRNA. | 1224 | GC-A0041 |
| IL3RA | NM_002183.4 | Human | Homo sapiens interleukin 3 receptor subunit alpha (IL3RA), transcript variant 1, mRNA. | 1137 | GC-A0042 |
| VDR | NM_001017535.2 | Human | Homo sapiens vitamin D receptor (VDR), transcript variant 2, mRNA. | 1284 | GC-A0043 |
| ADCY8 | NM_001115.3 | Human | Homo sapiens adenylate cyclase 8 (ADCY8), mRNA. | 3756 | GC-A0054 |
| CHRNA5 | NM_000745.4 | Human | Homo sapiens cholinergic receptor nicotinic alpha 5 subunit (CHRNA5), transcript variant 1, mRNA. | 1407 | GC-A0055 |
| EPHA3 | NM_005233.6 | Human | Homo sapiens EPH receptor A3 (EPHA3), transcript variant 1, mRNA. | 2952 | GC-A0059 |
| FPR2 | NM_001462.3 | Human | Homo sapiens formyl peptide receptor 2 (FPR2), transcript variant 1, mRNA. | 1056 | GC-A0060 |
| TGFBR2 | NM_003242.6 | Human | Homo sapiens transforming growth factor beta receptor 2 (TGFBR2), transcript variant 2, mRNA. | 1704 | GC-A0063 |
| IGFALS | NM_004970.3 | Human | Homo sapiens insulin like growth factor binding protein acid labile subunit (IGFALS), transcript variant 2, mRNA. | 1818 | GC-A0066 |
| TACR3 | NM_001059.3 | Human | Homo sapiens tachykinin receptor 3 (TACR3), mRNA. | 1398 | GC-A0068 |
| AGER | NM_001136.4 | Human | Homo sapiens advanced glycosylation end-product specific receptor (AGER), transcript variant 1, mRNA. | 1215 | GC-A0070 |
| ACVR2A | NM_001616.5 | Human | Homo sapiens activin A receptor type 2A (ACVR2A), transcript variant 2, mRNA. | 1542 | GC-A0075 |
| CXCR2 | NM_001557.4 | Human | Homo sapiens C-X-C motif chemokine receptor 2 (CXCR2), transcript variant 1, mRNA. | 1083 | GC-A0079 |
| SLC6A3 | NM_001044.5 | Human | Homo sapiens solute carrier family 6 member 3 (SLC6A3), mRNA. | 1863 | GC-A0080 |
| ADORA2B | NM_000676.4 | Human | Homo sapiens adenosine A2b receptor (ADORA2B), mRNA. | 999 | GC-A0085 |
| BRS3 | NM_001727.2 | Human | Homo sapiens bombesin receptor subtype 3 (BRS3), mRNA. | 1200 | GC-A0093 |
| ANG | NM_001145.4 | Human | Homo sapiens angiogenin (ANG), transcript variant 1, mRNA. | 444 | GC-A0098 |
| MAS1 | NM_002377.4 | Human | Homo sapiens MAS1 proto-oncogene, G protein-coupled receptor (MAS1), transcript variant 1, mRNA. | 978 | GC-A0099 |
| NGFR | NM_002507.4 | Human | Homo sapiens nerve growth factor receptor (NGFR), mRNA. | 1284 | GC-A0100 |
| BCHE | NM_000055.4 | Human | Homo sapiens butyrylcholinesterase (BCHE), transcript variant 1, mRNA. | 1809 | GC-A0103 |
| ICAM1 | NM_000201.3 | Human | Homo sapiens intercellular adhesion molecule 1 (ICAM1), mRNA. | 1599 | GC-A0111 |
| PTMS | NM_002824.6 | Human | Homo sapiens parathymosin (PTMS), transcript variant 2, mRNA. | 309 | GC-A0112 |
| AREG | NM_001657.4 | Human | Homo sapiens amphiregulin (AREG), mRNA. | 759 | GC-A0114 |
| PTPN1 | NM_002827.4 | Human | Homo sapiens protein tyrosine phosphatase non-receptor type 1 (PTPN1), transcript variant 1, mRNA. | 1308 | GC-A0118 |
| ACHE | NM_000665.5 | Human | Homo sapiens acetylcholinesterase (Cartwright blood group) (ACHE), transcript variant E4-E6, mRNA. | 1845 | GC-A0120 |
| KCNA5 | NM_002234.4 | Human | Homo sapiens potassium voltage-gated channel subfamily A member 5 (KCNA5), mRNA. | 1842 | GC-A0121 |
| EPHA2 | NM_004431.5 | Human | Homo sapiens EPH receptor A2 (EPHA2), transcript variant 1, mRNA. | 2931 | GC-A0125 |
| PTPN4 | NM_002830.4 | Human | Homo sapiens protein tyrosine phosphatase non-receptor type 4 (PTPN4), mRNA. | 2781 | GC-A0131 |
| GRPR | NM_005314.3 | Human | Homo sapiens gastrin releasing peptide receptor (GRPR), mRNA. | 1155 | GC-A0132 |
| IFNB1 | NM_002176.4 | Human | Homo sapiens interferon beta 1 (IFNB1), mRNA. | 564 | GC-A0137 |
| GABRA1 | NM_001127643.2 | Human | Homo sapiens gamma-aminobutyric acid type A receptor subunit alpha1 (GABRA1), transcript variant 2, mRNA. | 1371 | GC-A0140 |
| IL4R | NM_000418.4 | Human | Homo sapiens interleukin 4 receptor (IL4R), transcript variant 1, mRNA. | 2478 | GC-A0144 |
| PTPRE | NM_001316677.2 | Human | Homo sapiens protein tyrosine phosphatase receptor type E (PTPRE), transcript variant 4, mRNA. | 2103 | GC-A0148 |
