简介
G蛋白偶联受体（GPCRs）是一大类膜蛋白受体的统称，目前只有在真核生物中发现，广泛分布于中枢神经系统、免疫系统、心血管、视网膜等器官和组织，生理条件下正常工作的GPCRs主要由配体分子所激活，参与机体的发育和正常的功能行使。特异于多种配体，包括GPR25、GPR35、TAS2R20、CRHR2和OR6C74等。而如果与其相关的细胞内通路调节发生异常，或者外源病原物以之为受体攻击机体细胞，则会导致一系列疾病的发生。因此，GPCRs被视为重要的药物开发靶点，现代药物的靶标中超过34%是GPCRs。
套装信息
| 新货号 | 旧货号 | 物种 | 基因数 | 载体 | 载体类型 | 价格 |
|---|---|---|---|---|---|---|
| OC-GF007-M02 | OC-HGR-M02 | Human | 875 | pReceiver-M02 | Expression-ready Non-viral | Inquire |
| OC-GF007-M35 | OC-HGR-M35 | Human | 875 | pReceiver-M35 | Expression-ready Non-viral | Inquire |
| OC-GF007-M98 | OC-HGR-M98 | Human | 875 | pReceiver-M98 | Expression-ready Non-viral | Inquire |
| OC-GF007-Lv105 | OC-HGR-Lv105 | Human | 875 | pReceiver-Lv105 | Expression-ready Lentiviral | Inquire |
| OC-GF007-Lv242 | OC-HGR-Lv242 | Human | 875 | pReceiver-Lv242 | Expression-ready Lentiviral | Inquire |
| OC-GF007-GC | OC-HGR-GC | Human | 875 | pDONR™ Vector | Gateway shuttle | Inquire |
克隆列表
表格仅包含克隆套装部分内容，如需更多信息请通过电话（4006-020-200）或邮件（sales@igenebio.com）联系我们。
| Symbol | NCBI注册号 | 物种 | 基因描述 | ORF length(bp) | 产品ID |
| TACR1 | NM_001058.4 | Human | Homo sapiens tachykinin receptor 1 (TACR1), transcript variant long, mRNA. | 1224 | GC-A0041 |
| FPR2 | NM_001462.3 | Human | Homo sapiens formyl peptide receptor 2 (FPR2), transcript variant 1, mRNA. | 1056 | GC-A0060 |
| TACR3 | NM_001059.3 | Human | Homo sapiens tachykinin receptor 3 (TACR3), mRNA. | 1398 | GC-A0068 |
| CXCR2 | NM_001557.4 | Human | Homo sapiens C-X-C motif chemokine receptor 2 (CXCR2), transcript variant 1, mRNA. | 1083 | GC-A0079 |
| ADORA2B | NM_000676.4 | Human | Homo sapiens adenosine A2b receptor (ADORA2B), mRNA. | 999 | GC-A0085 |
| NPY | NM_000905.4 | Human | Homo sapiens neuropeptide Y (NPY), mRNA. | 294 | GC-A0089 |
| BRS3 | NM_001727.2 | Human | Homo sapiens bombesin receptor subtype 3 (BRS3), mRNA. | 1200 | GC-A0093 |
| MAS1 | NM_002377.4 | Human | Homo sapiens MAS1 proto-oncogene, G protein-coupled receptor (MAS1), transcript variant 1, mRNA. | 978 | GC-A0099 |
| GRPR | NM_005314.3 | Human | Homo sapiens gastrin releasing peptide receptor (GRPR), mRNA. | 1155 | GC-A0132 |
| NPY1R | NM_000909.6 | Human | Homo sapiens neuropeptide Y receptor Y1 (NPY1R), mRNA. | 1155 | GC-A0167 |
| ADRA2C | NM_000683.4 | Human | Homo sapiens adrenoceptor alpha 2C (ADRA2C), mRNA. | 1389 | GC-A0187 |
| GHRHR | NM_000823.4 | Human | Homo sapiens growth hormone releasing hormone receptor (GHRHR), mRNA. | 1272 | GC-A0191 |
| PTH1R | NM_001184744.1 | Human | Homo sapiens parathyroid hormone 1 receptor (PTH1R), transcript variant 2, mRNA. | 1782 | GC-A0198 |
| GPR183 | NM_004951.5 | Human | Homo sapiens G protein-coupled receptor 183 (GPR183), mRNA. | 1086 | GC-A0214 |
| CCKAR | NM_000730.3 | Human | Homo sapiens cholecystokinin A receptor (CCKAR), mRNA. | 1287 | GC-A0232 |
| EDNRB | NM_001122659.2 | Human | Homo sapiens endothelin receptor type B (EDNRB), transcript variant 3, mRNA. | 1329 | GC-A0293 |
| PTHLH | NM_198964.2 | Human | Homo sapiens parathyroid hormone like hormone (PTHLH), transcript variant 3, mRNA. | 528 | GC-A0295 |
| ADORA2A | NM_001278499.2 | Human | Homo sapiens adenosine A2a receptor (ADORA2A), transcript variant 4, mRNA. | 1239 | GC-A0315 |
| TMEM11 | NM_003876.3 | Human | Homo sapiens transmembrane protein 11 (TMEM11), transcript variant 1, mRNA; nuclear gene for mitochondrial product. | 579 | GC-A0331 |
| PTAFR | NM_001164723.3 | Human | Homo sapiens platelet activating factor receptor (PTAFR), transcript variant 4, mRNA. | 1029 | GC-A0357 |
| HTR1E | NM_000865.3 | Human | Homo sapiens 5-hydroxytryptamine receptor 1E (HTR1E), mRNA. | 1098 | GC-A0398 |
| CHRM3 | NM_001347716.2 | Human | Homo sapiens cholinergic receptor muscarinic 3 (CHRM3), transcript variant 1, mRNA. | 1773 | GC-A0401 |
| AVPR2 | NM_000054.7 | Human | Homo sapiens arginine vasopressin receptor 2 (AVPR2), transcript variant 1, mRNA. | 1116 | GC-A0411 |
| AGTR1 | NM_000685.5 | Human | Homo sapiens angiotensin II receptor type 1 (AGTR1), transcript variant 1, mRNA. | 1080 | GC-A0417 |
| CXCR4 | NM_003467.3 | Human | Homo sapiens C-X-C motif chemokine receptor 4 (CXCR4), transcript variant 2, mRNA. | 1059 | GC-A0419 |
| HTR1B | NM_000863.3 | Human | Homo sapiens 5-hydroxytryptamine receptor 1B (HTR1B), mRNA. | 1173 | GC-A0434 |
| HTR1D | NM_000864.5 | Human | Homo sapiens 5-hydroxytryptamine receptor 1D (HTR1D), mRNA. | 1134 | GC-A0435 |
| CHRM2 | NM_001006630.2 | Human | Homo sapiens cholinergic receptor muscarinic 2 (CHRM2), transcript variant 1, mRNA. | 1401 | GC-A0448 |
| GNRHR | NM_000406.3 | Human | Homo sapiens gonadotropin releasing hormone receptor (GNRHR), transcript variant 1, mRNA. | 987 | GC-A0455 |
| DRD1 | NM_000794.5 | Human | Homo sapiens dopamine receptor D1 (DRD1), mRNA. | 1341 | GC-A0462 |
| CNR2 | NM_001841.3 | Human | Homo sapiens cannabinoid receptor 2 (CNR2), mRNA. | 1083 | GC-A0463 |
| GRK6 | NM_001004106.3 | Human | Homo sapiens G protein-coupled receptor kinase 6 (GRK6), transcript variant 1, mRNA. | 1731 | GC-A0473 |
| GCGR | NM_000160.5 | Human | Homo sapiens glucagon receptor (GCGR), mRNA. | 1434 | GC-A0475 |
| PTGER1 | NM_000955.3 | Human | Homo sapiens prostaglandin E receptor 1 (PTGER1), mRNA. | 1209 | GC-A0480 |
| FPR3 | NM_002030.5 | Human | Homo sapiens formyl peptide receptor 3 (FPR3), mRNA. | 1062 | GC-A0497 |
| ADORA1 | NM_001048230.2 | Human | Homo sapiens adenosine A1 receptor (ADORA1), transcript variant 2, mRNA. | 981 | GC-A0504 |
| GLP1R | NM_002062.5 | Human | Homo sapiens glucagon like peptide 1 receptor (GLP1R), transcript variant 1, mRNA. | 1392 | GC-A0510 |
| TBXA2R | NM_001060.6 | Human | Homo sapiens thromboxane A2 receptor (TBXA2R), transcript variant a, mRNA. | 1032 | GC-A0516 |
| HTR2A | NM_000621.5 | Human | Homo sapiens 5-hydroxytryptamine receptor 2A (HTR2A), transcript variant 1, mRNA. | 1416 | GC-A0533 |
| AVPR1B | NM_000707.5 | Human | Homo sapiens arginine vasopressin receptor 1B (AVPR1B), mRNA. | 1275 | GC-A0541 |
| GPR176 | NM_007223.3 | Human | Homo sapiens G protein-coupled receptor 176 (GPR176), transcript variant 1, mRNA. | 1548 | GC-A0542 |
| HTR1F | NM_001322210.2 | Human | Homo sapiens 5-hydroxytryptamine receptor 1F (HTR1F), transcript variant 3, mRNA. | 1101 | GC-A0549 |
| NPR3 | NM_000908.4 | Human | Homo sapiens natriuretic peptide receptor 3 (NPR3), transcript variant 2, mRNA. | 1623 | GC-A0569 |
| GPR12 | NM_005288.4 | Human | Homo sapiens G protein-coupled receptor 12 (GPR12), mRNA. | 1005 | GC-A0597 |
| NTSR1 | NM_002531.3 | Human | Homo sapiens neurotensin receptor 1 (NTSR1), mRNA. | 1257 | GC-A0601 |
| PTGER2 | NM_000956.4 | Human | Homo sapiens prostaglandin E receptor 2 (PTGER2), mRNA. | 1077 | GC-A0602 |
| NPBWR1 | NM_005285.5 | Human | Homo sapiens neuropeptides B and W receptor 1 (NPBWR1), mRNA. | 987 | GC-A0607 |
| NPBWR2 | NM_005286.4 | Human | Homo sapiens neuropeptides B and W receptor 2 (NPBWR2), mRNA. | 1002 | GC-A0608 |
| PTH2R | NM_005048.4 | Human | Homo sapiens parathyroid hormone 2 receptor (PTH2R), transcript variant 1, mRNA. | 1653 | GC-A0612 |
| CCR3 | NM_001837.4 | Human | Homo sapiens C-C motif chemokine receptor 3 (CCR3), transcript variant 1, mRNA. | 1068 | GC-A0619 |
