简介
核激素受体（Nuclear hormone receptors）指的是细胞核内激素作用的靶分子，属于核受体。类固醇激素受体和非类固醇激素受体统称为核激素受体，类固醇激素受体又称I型核受体，包括雌激素受体ER、雄激素受体AR、孕酮受体PGR和糖皮质激素受体GR。非类固醇激素受体又称II型核受体，包括甲状腺激素受体THR、视黄酸受体RARα，维生素D受体VDR和过氧化物酶增殖物活化受体PPARγ。与在细胞表面的受体不同，这类受体仅存在于后生动物（如线虫、昆虫和脊椎动物）中，多为反式作用因子，当与相应的激素结合后，能与DNA的顺式作用元件结合，调节基因转录，从而在机体的生长发育、新陈代谢、细胞分化及体内许多生理过程中发挥重要作用。这类受体的功能障碍将导致一系列疾病如癌症、不育、肥胖、糖尿病等。
套装信息
| 货号 | 物种 | 基因数 | 载体 | 载体类型 | 价格 |
|---|---|---|---|---|---|
| OC-HNH-M02 | Human | 73 | pReceiver-M02 | Expression-ready Non-viral | Inquire |
| OC-HNH-M35 | Human | 73 | pReceiver-M35 | Expression-ready Non-viral | Inquire |
| OC-HNH-M98 | Human | 73 | pReceiver-M98 | Expression-ready Non-viral | Inquire |
| OC-HNH-Lv105 | Human | 73 | pReceiver-Lv105 | Expression-ready Non-viral | Inquire |
| OC-HNH-Lv242 | Human | 73 | pReceiver-Lv242 | Expression-ready Lentiviral | Inquire |
| OC-HNH-GC | Human | 73 | pDONR™ Vector | Gateway shuttle | Inquire |
克隆列表
表格仅包含克隆套装部分内容，如需更多信息请通过电话（4006-020-200）或邮件（sales@igenebio.com）联系我们。
| Symbol | NCBI注册号 | 物种 | 基因描述 | ORF length(bp) | 产品ID |
| VDR | NM_001017535.2 | Human | Homo sapiens vitamin D receptor (VDR), transcript variant 2, mRNA. | 1284 | GC-A0043 |
| GHRHR | NM_000823.4 | Human | Homo sapiens growth hormone releasing hormone receptor (GHRHR), mRNA. | 1272 | GC-A0191 |
| ESR1 | NM_000125.3 | Human | Homo sapiens estrogen receptor 1 (ESR1), transcript variant 1, mRNA. | 1788 | GC-A0322 |
| RXRB | NM_021976.5 | Human | Homo sapiens retinoid X receptor beta (RXRB), transcript variant 2, mRNA. | 1602 | GC-A0346 |
| GNRHR | NM_000406.3 | Human | Homo sapiens gonadotropin releasing hormone receptor (GNRHR), transcript variant 1, mRNA. | 987 | GC-A0455 |
| AHR | NM_001621.5 | Human | Homo sapiens aryl hydrocarbon receptor (AHR), mRNA. | 2547 | GC-A0474 |
| GHR | NM_001242401.4 | Human | Homo sapiens growth hormone receptor (GHR), transcript variant 4, mRNA. | 1917 | GC-A0521 |
| RXRA | NM_002957.6 | Human | Homo sapiens retinoid X receptor alpha (RXRA), transcript variant 1, mRNA. | 1389 | GC-A0529 |
| NR0B1 | NM_000475.5 | Human | Homo sapiens nuclear receptor subfamily 0 group B member 1 (NR0B1), mRNA. | 1413 | GC-A0573 |
| CRHR2 | NM_001883.5 | Human | Homo sapiens corticotropin releasing hormone receptor 2 (CRHR2), transcript variant 1, mRNA. | 1236 | GC-A0634 |
| NR1D1 | NM_021724.5 | Human | Homo sapiens nuclear receptor subfamily 1 group D member 1 (NR1D1), mRNA. | 1845 | GC-A0803 |
| THRA | NM_001190919.2 | Human | Homo sapiens thyroid hormone receptor alpha (THRA), transcript variant 4, mRNA. | 1473 | GC-A0835 |
| NR3C1 | NM_001024094.2 | Human | Homo sapiens nuclear receptor subfamily 3 group C member 1 (NR3C1), transcript variant 7, mRNA. | 2337 | GC-A0857 |
| NR1I3 | NM_005122.5 | Human | Homo sapiens nuclear receptor subfamily 1 group I member 3 (NR1I3), transcript variant 3, mRNA. | 1047 | GC-A0964 |
| TRHR | NM_003301.7 | Human | Homo sapiens thyrotropin releasing hormone receptor (TRHR), mRNA. | 1197 | GC-A0971 |
| NR2F1 | NM_005654.6 | Human | Homo sapiens nuclear receptor subfamily 2 group F member 1 (NR2F1), mRNA. | 1272 | GC-A1000 |
| NR1H3 | NM_005693.4 | Human | Homo sapiens nuclear receptor subfamily 1 group H member 3 (NR1H3), transcript variant 1, mRNA. | 1344 | GC-A1306 |
| NR2F2 | NM_021005.4 | Human | Homo sapiens nuclear receptor subfamily 2 group F member 2 (NR2F2), transcript variant 1, mRNA. | 1245 | GC-C0221 |
| ESRRG | NM_001438.4 | Human | Homo sapiens estrogen related receptor gamma (ESRRG), transcript variant 1, mRNA. | 1377 | GC-E0424 |
| PPARD | NM_006238.5 | Human | Homo sapiens peroxisome proliferator activated receptor delta (PPARD), transcript variant 1, mRNA. | 1326 | GC-G0246 |
| RARA | NM_001145301.3 | Human | Homo sapiens retinoic acid receptor alpha (RARA), transcript variant 3, mRNA. | 1389 | GC-H0048 |
| NR4A2 | NM_006186.4 | Human | Homo sapiens nuclear receptor subfamily 4 group A member 2 (NR4A2), transcript variant 1, mRNA. | 1797 | GC-I0539 |
| NR1H2 | NM_007121.5 | Human | Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 1, mRNA. | 1386 | GC-M0003 |
| NR4A3 | NM_173199.4 | Human | Homo sapiens nuclear receptor subfamily 4 group A member 3 (NR4A3), transcript variant 4, mRNA. | 1332 | GC-M0934 |
| NR1D2 | NM_005126.5 | Human | Homo sapiens nuclear receptor subfamily 1 group D member 2 (NR1D2), transcript variant 1, mRNA. | 1740 | GC-P0004 |
| NR5A1 | NM_004959.5 | Human | Homo sapiens nuclear receptor subfamily 5 group A member 1 (NR5A1), mRNA. | 1386 | GC-P0006 |
| NR6A1 | NM_033334.4 | Human | Homo sapiens nuclear receptor subfamily 6 group A member 1 (NR6A1), transcript variant 1, mRNA. | 1443 | GC-P0009 |
| NR2E3 | NM_014249.4 | Human | Homo sapiens nuclear receptor subfamily 2 group E member 3 (NR2E3), transcript variant 2, mRNA. | 1233 | GC-P0012 |
| RARB | NM_001290217.2 | Human | Homo sapiens retinoic acid receptor beta (RARB), transcript variant 4, mRNA. | 1011 | GC-P0014 |
| NR2E1 | NM_003269.5 | Human | Homo sapiens nuclear receptor subfamily 2 group E member 1 (NR2E1), transcript variant 2, mRNA. | 1158 | GC-P0019 |
| PPARG | NM_015869.5 | Human | Homo sapiens peroxisome proliferator activated receptor gamma (PPARG), transcript variant 2, mRNA. | 1518 | GC-Q0148 |
| NR5A2 | NM_003822.5 | Human | Homo sapiens nuclear receptor subfamily 5 group A member 2 (NR5A2), transcript variant 2, mRNA. | 1488 | GC-Q0618 |
| TRH | NM_007117.5 | Human | Homo sapiens thyrotropin releasing hormone (TRH), mRNA. | 729 | GC-S0380 |
| RORA | NM_134260.2 | Human | Homo sapiens RAR related orphan receptor A (RORA), transcript variant 2, mRNA. | 1671 | GC-T0080 |
| RARG | NM_000966.6 | Human | Homo sapiens retinoic acid receptor gamma (RARG), transcript variant 1, mRNA. | 1365 | GC-T0175 |
| NR1H4 | NM_005123.4 | Human | Homo sapiens nuclear receptor subfamily 1 group H member 4 (NR1H4), transcript variant 2, mRNA. | 1419 | GC-T0601 |
| NR0B2 | NM_021969.3 | Human | Homo sapiens nuclear receptor subfamily 0 group B member 2 (NR0B2), mRNA. | 774 | GC-T1368 |
| NR1I2 | NM_022002.3 | Human | Homo sapiens nuclear receptor subfamily 1 group I member 2 (NR1I2), transcript variant 2, mRNA. | 1422 | GC-T2079 |
| RORA | NM_134261.2 | Human | Homo sapiens RAR related orphan receptor A (RORA), transcript variant 1, mRNA. | 1572 | GC-T3100 |
| RORC | NM_001001523.2 | Human | Homo sapiens RAR related orphan receptor C (RORC), transcript variant 2, mRNA. | 1494 | GC-T6988 |
| PTGER3 | NM_198716.2 | Human | Homo sapiens prostaglandin E receptor 3 (PTGER3), transcript variant 6, mRNA. | 1125 | GC-T7970 |
| THRB | NM_001252634.2 | Human | Homo sapiens thyroid hormone receptor beta (THRB), transcript variant 4, mRNA. | 1386 | GC-T9450 |
| ESR2 | NM_001437.3 | Human | Homo sapiens estrogen receptor 2 (ESR2), transcript variant a, mRNA. | 1593 | GC-U0033 |
| GHSR | NM_004122.2 | Human | Homo sapiens growth hormone secretagogue receptor (GHSR), transcript variant 1b, mRNA. | 870 | GC-U0190 |
| NR2E3 | NM_016346.4 | Human | Homo sapiens nuclear receptor subfamily 2 group E member 3 (NR2E3), transcript variant 1, mRNA. | 1104 | GC-X0397 |
| GHSR | NM_198407.2 | Human | Homo sapiens growth hormone secretagogue receptor (GHSR), transcript variant 1a, mRNA. | 1101 | GC-X0963 |
| PTGER3 | NM_198719.2 | Human | Homo sapiens prostaglandin E receptor 3 (PTGER3), transcript variant 9, mRNA. | 1173 | GC-Y0003 |
| PTGER3 | NM_198715.3 | Human | Homo sapiens prostaglandin E receptor 3 (PTGER3), transcript variant 5, mRNA. | 1167 | GC-Y0004 |
| PTGER3 | NM_198717.2 | Human | Homo sapiens prostaglandin E receptor 3 (PTGER3), transcript variant 7, mRNA. | 1098 | GC-Y0005 |
| NR1H3 | NM_001130101.3 | Human | Homo sapiens nuclear receptor subfamily 1 group H member 3 (NR1H3), transcript variant 2, mRNA. | 1164 | GC-Z0276 |
