Recombinant Human ALDH1A1 Protein Data Sheet
| Catalog # | hRP-U0011-EF012 |
| Size | 100 μg |
| Protein Name | Human retinal dehydrogenase 1 |
| Protein Symbol | ALDH1A1 |
| Original Source | Homo sapiens |
| Expression System | E.coli |
| GenBank Accession # | NM_000689.1 |
| Uniprot Accession # | P00352 |
| Description | This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes. |
| Application | WB, ELISA, IP, antibody production, protein array |
| Fusion tag | N-His |
| Peptide Length | 516aa(including fusion tag) |
| Molecular Weight | 56.8kDa(including fusion tag) |
| pI | 7.0 |
| Activity | NA |
| Storage | Storage buffer: 20mM Tris.Cl, 50mM NaCl, 20% Glycerol, pH9.0. Store at -80°C and avoid repeated freeze-thaw cycles. |
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