启动子报告克隆（Promoter Reporter Clones）

• Yang, X., et al. (2025). E2F1-mediated ESPL1 transcriptional activation predicts poor prognosis and promotes the proliferation of leiomyosarcoma. Cytojournal DOI: 10.25259/Cytojournal_178_2024 [GLuc-ON™ Human ESPL1 Promoter Reporter Clone]
• Drosen, M.E., et al. (2025). Inactivation of ATG13 stimulates chronic demyelinating pathologies in muscle-serving nerves and spinal cord. Immunol Res DOI: 10.1007/s12026-024-09557-7 [GLuc-ON™ IL6 Promoter Reporter Clone]

• Lee, C-J., et al. (2024). The dysadherin/MMP9 axis modifies the extracellular matrix to accelerate colorectal cancer progression. Nat Commun DOI: 10.1038/s41467-024-54920-9 [GLuc-ON™ MMP9 Promoter Reporter Clone, Cat. No. HPRM45843]
• Qu, L., et al. (2024). FBXL16: a new regulator of neuroinflammation and cognition in Alzheimer’s disease through the ubiquitination-dependent degradation of amyloid precursor protein. Biomark Res DOI: 10.1186/s40364-024-00691-w [GLuc-ON™ FBXL16 Promoter Reporter Clone, Cat. No. HPRM53066]
• Chuang, T-D., et al. (2024). The Functional Role of the Long Non-Coding RNA LINCMD1 in Leiomyoma Pathogenesis. Int J Mol Sci DOI: 10.3390/ijms252111539 [3′ UTR target vector pEZX-MT01]
• Kyung, D.S., et al. (2024). Single-cell transcriptomic analysis reveals dynamic activation of cellular signaling pathways regulating beige adipogenesis. Exp Mol Med DOI: 10.1038/s12276-024-01252-9 [GLuc-ON™ DPP4 Promoter Reporter Clone, Cat. No. MPRM34034; Secrete-Pair™ Dual Luminescence Assay Kit, Cat. No. LF031]
• Tao, J., et al. (2024). ΔNp63α promotes radioresistance in esophageal squamous cell carcinoma through the PLEC-KEAP1-NRF2 feedback loop. Cell Death Dis DOI: 10.1038/s41419-024-07194-4 [Gluc-On™ promoter reporter vector, Cat. No. pEZX-PG04; Secrete-Pair™ Dual Luminescence Assay Kit, Cat. No. LF031]
• Hsieh, C-W., et al .(2024). Indoxyl Sulfate Inhibits Osteogenesis in Bone Marrow Mesenchymal Stem Cells through the AhR/Hes1 Pathway. Int J Mol Sci DOI: 10.3390/ijms25168770 [GLuc-ON™ Bmp2 or Runx2 Promoter Reporter Clone]
• Burton, E.A., et al. (2024). Variant-to-function mapping of late-onset Alzheimer’s disease GWAS signals in human microglial cell models implicates RTFDC1 at the CASS4 locus. bioRxiv DOI: 10.1101/2024.08.22.609230 [GLuc-ON™ RTFDC1 Promoter Reporter Clone, Cat. No. HPRM41362-PF02]
• Yang, B., et al. (2024). The role of forkhead box M1-methionine adenosyltransferase 2 A/2B axis in liver inflammation and fibrosis. Nat Commun DOI: 10.1038/s41467-024-52527-8 [GLuc-ON™ human FOXM1 promoter-reporter clone]
• Littleton, S.H., et al. (2024). Protocol to study cis-regulatory activity of GWAS loci for specific gene promoters in human primary astrocytes using luciferase reporter assay. STAR Protoc DOI: 10.1016/j.xpro.2024.103338 [GLuc-ON™ FAIM2 Promoter Reporter Clone, Cat. No. HPRM47354-PG02]
• Wen, Y-C., et al. (2024). The oncogenic ADAMTS1–VCAN–EGFR cyclic axis drives anoikis resistance and invasion in renal cell carcinoma. Cell Mol Biol Lett DOI: 10.1186/s11658-024-00643-0 [GLuc-ON™ EGFR Promoter Reporter Clone, Cat. No. HPRM45993]
• Janakiraman, H., et al. (2024). Targeting SNAI1-Mediated Colorectal Cancer Chemoresistance and Stemness by Sphingosine Kinase 2 Inhibition. World J Oncol DOI: 10.14740/wjon1890 [GLuc-ON™ Human SPHK2 Promoter Reporter Clones, Cat. No. HPRM60421-PG04; Secrete-Pair™ Dual Luminescence Assay Kit, Cat. No. LF031]
• Yang, B., et al. (2024). Tumor-associated macrophages/C-X-C motif chemokine ligand 1 promotes breast cancer autophagy-mediated chemoresistance via IGF1R/STAT3/HMGB1 signaling. Cell Death Dis DOI: 10.1038/s41419-024-07123-5 [GLuc-ON™ Human HMGB1 Promoter Reporter Clone, Cat. No. HPRM43498-PG04; Secrete-Pair™ Dual Luminescence Assay Kit, Cat. No. LF031]
• Sun, X., et al. (2024). Genetic and epigenetic regulation of cortactin (CTTN) by inflammatory factors and mechanical stress in human lung endothelial cells. Biosci Rep DOI: 10.1042/BSR20231934 [GLuc-ON™ Promoter Reporter Clones vector pEZX-PG04-CTTN]
• Thuy, P.X., et al. (2024). Vinblastine Resistance Is Associated with Nephronophthisis 3-Mediated Primary Cilia via Intraflagellar Transport Protein 88 and Apoptosis-Antagonizing Transcription Factor. Int J Mol Sci DOI: 10.3390/ijms251910369 [GLuc-ON™ IFT88 Promoter Reporter Clones, Cat. No. HPRM46777]
• Mauro-Lizcano, M., et al. (2024). Mitophagy and cancer: role of BNIP3/BNIP3L as energetic drivers of stemness features; ATP production; proliferation; and cell migration. Aging (Albany NY). DOI: 10.18632/aging.205939 [GLuc-ON™ BNIP3 and BNIP3L Promoter Reporter Clones, Cat. No. HPRM45275-LvPF02, HPRM45442- LvPF02]
• Bidooki, S.H., et al. (2024). TXNDC5 Plays a Crucial Role in Regulating Endoplasmic Reticulum Activity through Different ER Stress Signaling Pathways in Hepatic Cells. Int J Mol Sci. DOI: 10.3390/ijms25137128 [GLuc-ON™ Txndc5 Promoter Reporter Clones]
• Patterson, M.R., et al. (2024). The Hippo pathway transcription factors YAP and TAZ play HPV-type dependent roles in cervical cancer. Nat Commun. DOI: 10.1038/s41467-024-49965-9 [GLuc-ON™ Human WWTR1 Promoter Reporter Clone]
• Liu, Q., et al. (2024). IKZF1 and UBR4 gene variants drive autoimmunity and Th2 polarization in IgG4-related disease. J Clin Invest. DOI: 10.1172/JCI178692 [GLuc-ON™ Human FYN promoter reporter clone, Cat. No. HPRM53014-LvPG04; Secrete-Pair™ Dual Luminescence Assay Kit, Cat. No. LF031]
• Quintanal-Villalonga, A., et al. (2024). CDC7 inhibition impairs neuroendocrine transformation in lung and prostate tumors through MYC degradation. Signal Transduct Target Ther. DOI: 10.1038/s41392-024-01908-y [GLuc-ON™ CDC7 promoter reporter clone and control clones, Cat. No. HPRM35138-LvPG04, GAPDH-LvPG04, NEG-LvPG04; Secrete-Pair™ Dual Luminescence Assay Kit, Cat. No. LF032]
• Littleton, S.H., et al. (2024). Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2. Cell Genom. DOI: 10.1016/j.xgen.2024.100556 [OmicsLink™ miRNA 3′ UTR target lentiviral clones; GLuc-ON™ Promoter Reporter Clones]
• Durand, S., et al. (2024). ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions. Oncogene. DOI: 10.1038/s41388-024-03010-7 [GLuc-ON™ MITF promoter reporter clone]
• Park, J.H., et al. (2024). Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression. Nat Commun. DOI: 10.1038/s41467-024-48441-8 [GLuc-ON™ mouse Il33 promoter reporter clone, Cat. No. MPRM34949-PG02]
• Ampudia-Mesias, E., et al. (2024). The OTX2 Gene Induces Tumor Growth and Triggers Leptomeningeal Metastasis by Regulating the mTORC2 Signaling Pathway in Group 3 Medulloblastomas. Int J Mol Sci. DOI: 10.3390/ijms25084416 [GLuc-ON™ mTOR promoter-reporter clone]
• Prunotto, P., et al. (2024). The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons. Cell Death Dis. DOI: 10.1038/s41419-024-06655-0 [GLuc-ON™ Human Plasminogen Activator promoter-reporter clone, Cat. No.HPRM12655-PF02]
• Zhao, Y., et al. (2024). Developing liver-targeted naringenin nanoparticles for breast cancer endocrine therapy by promoting estrogen metabolism. J Nanobiotechnology. DOI: 10.1186/s12951-024-02356-0 [GLuc-ON™ EST Promoter Reporter Clone, Cat. No.pEZX-LvPG04; Luc-Pair Duo-Luciferase Assay Kits 2.0, Cat. No.LF001]
• Yang Song, et al. 2024. Biphasic regulation of epigenetic state by matrix stiffness during cell reprogramming. Sci Adv. DOI: 10.1126/sciadv.adk0639 [GLuc-ON™ Mouse Ascl1 promoter-reporter clone, Cat. No.MPRM39894-LvPF02]
• Mathias Linnerbauer, et al. 2024. The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology. Nat Immunol. DOI: 10.1038/s41590-024-01756-6 [GLuc-ON™ HBEGF promoter-reporter clone]
• Niklas Dörmann, et al. 2024. Metabolic remodeling in cardiac hypertrophy and heart failure with reduced ejection fraction occurs independent of transcription factor EB in mice. Front Cardiovasc Med. DOI: 10.3389/fcvm.2023.1323760. [GLuc-ON™ PPARGC1A Promoter Reporter Clones]
• Chao Su, et al. 2024. Vascular injury activates the ELK1/SND1/SRF pathway to promote vascular smooth muscle cell proliferative phenotype and neointimal hyperplasia. Cell Mol Life Sci. DOI: 10.1007/s00018-023-05095-x [GLuc-ON™ Promoter Reporter Clones(EZX-LvPG04)] 
• Chaeyoung Lee, et al. 2024. Hedgehog signalling is involved in acquired resistance to KRASG12C inhibitors in lung cancer cells. Cell Death Dis. DOI:10.1038/s41419-024-06436-9. [GLuc-ON™ KRAS promoter reporter clones, Cat. No.HPRM45839-PG04; Secrete-Pair™ Dual Luminescence Assay Kit, Cat. No.LF031] 
• Kunxiang Gong, et al. 2024. ZSWIM4 inhibition improves chemosensitivity in epithelial ovarian cancer cells by suppressing intracellular glycine biosynthesis. J Transl Med. DOI:10.1186/s12967-024-04980-8. [OMICSLINK™ shRNA clone set against Human ZSWIM4; GLuc-ON™ Human ZSWIM4 promoter-reporter clone; OMICSLINK™ Human FOXK1 ORF expression clone] 

• Abdelhalim Azzi, et al. 2023. The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway. iScience. DOI: 10.1016/j.isci.2023.107449 [Secrete-Pair™ Gaussia Luciferase kit; GLuc-ON™ YAP1 promoter-reporter clone, Cat. No.HPRM34974-PG02]
• Jia-Jun Li, et al. 2023. The liver microenvironment orchestrates FGL1-mediated immune escape and progression of metastatic colorectal cancer. Nat Commun. DOI: 10.1038/s41467-023-42332-0 [OMICSLINK™ Human or Mouse OTUD1, p65 ORF expression clone; OMICSLINK™ shRNA clone against Human or Mouse OTUD1, p65; GLuc-ON™ Human or Mouse OTUD1 promoter-reporter clone, Cat. No.MPRM62853]
• Katharina Jonas, et al. 2023. MiR-4646-5p Acts as a Tumor-Suppressive Factor in Triple Negative Breast Cancer and Targets the Cholesterol Transport Protein GRAMD1B. Noncoding RNA. DOI: 10.3390/ncrna10010002 [miTarget™ miRNA 3′ UTR clone targeting GRAMD1B containing a predicted binding site was inserted into the dual luciferase reporter vector pEZX-MT06]
• Chun Wai Wong, et al. 2023. PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven acquired resistance in preclinical cancer models. Nat Commun.DOI:10.1038/s41467-023-41737-1. [GLuc-ON™ Human PARP14 promoter-reporter clone; Secrete-Pair™ Dual Luminescence Assay Kit, Cat. No.HPRM48858]
• Cuicui Xiao, et al. 2023. E2F1-mediated Up-regulation of NCAPG Promotes Hepatocellular Carcinoma Development by Inhibiting Pyroptosis. J Clin Transl Hepatol. DOI:10.14218/JCTH.2022.00292. [GLuc-ON™ Human NCAPG (−2 to +0.2 kb) promoter-reporter clone, Cat.No.CS-HPRM24637-FR01]
• Manish Chamoli, et al. 2023. A drug-like molecule engages nuclear hormone receptor DAF-12/FXR to regulate mitophagy and extend lifespan. Nat Aging.DOI:10.1038/s43587-023-00524-9. [Secrete-Pair™ Gaussia Luciferase reporter vector]
• Shuyan Yang, et al. 2023. adducin 1 is essential for the survival of erythroid precursors via regulating p53 transcription in zebrafish. iScience. DOI:10.1016/j.isci.2023.107516. [luciferase reporter gene vector pEZX-FR01] 
• Katharina Jonas, et al. 2023. MiR-4649-5p acts as a tumor-suppressive microRNA in triple negative breast cancer by direct interaction with PIP5K1C; thereby potentiating growth-inhibitory effects of the AKT inhibitor capivasertib. Breast Cancer Res. DOI:10.1186/s13058-023-01716-2. [PIP5K1C  3’UTR luciferase reporter clone pEZX-MT06; Luc-Pair™ Duo-Luciferase Assay Kit 2.0, Cat.No.LF001]
• Yiqiu Li, et al. 2023. Intracellular Fusobacterium nucleatum infection attenuates antitumor immunity in esophageal squamous cell carcinoma. Nat Commun.DOI:10.1038/s41467-023-40987-3. [OMICSLINK™ Human ATF3 ORF expression clone, Cat. No.EX-F0674-M35; GLuc-ON™ Human CD274 promoter-reporter clone, Cat. No.HPRM40139]
• Yu, C., et al. (2023). Flot2 acts as a novel mediator of podocyte injury in proteinuric kidney disease. Int J Biol Sci doi:10.7150/ijbs.78945[OMICSLINK™ empty vector; GLuc-ON™ promoter reporter clone; Lenti-Pac™ HIV Expression Packing Kit; Secrete-Pair™ Dual Luminescence Assay Kit]
• Zhang, Y., et al. (2023). ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression. Cell reports doi: 10.1016/j.celrep.2023.112654 [GLuc-ON™ promoter-reporter clone; Secrete-Pair™ Luciferase Assay Kit]
• Quintanal-Villalonga, A., et al. (2023). Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers. SCIENCE TRANSLATIONAL MEDICINE doi: 10.1126/scitranslmed.adf7006 [GLuc-ON™ promoter-reporter clone; OMICSLINK™ ORF expression control clones]
• Yang, Y.C., et al. (2023). The RNA-binding protein KSRP aggravates malignant progression of clear cell renal cell carcinoma through transcriptional inhibition and post-transcriptional destabilization of the NEDD4L ubiquitin ligase. J Biomed Sci doi: 10.1186/s12929-023-00949-9 [GLuc-ON™ promoter-reporter clone; Secrete-Pair™ Gaussia Luciferase Assay kit]
• Morelli, E., et al. (2023). A MIR17HG-derived long noncoding RNA provides an essential chromatin scaffold for protein interaction and myeloma growth. Blood doi: 10.1182/blood.2022016892 [GLuc-ON™ Promoter Reporter Vector]
• Kalantari, P., et al. (2023). The balance between gasdermin D and STING signaling shapes the severity of schistosome immunopathology. PNAS doi: 10.1073/pnas.2211047120 [GLuc-ON™ Promoter Reporter Vector]
• Pflug, K.M., et al. (2023). Transcriptional induction of NF-κB-inducing kinase by E2F4/5 facilitates collective invasion of GBM cells. Sci Rep doi: 10.1038/s41598-023-38996-9 [GLuc-ON™ NIK promoter-reporter clone]
• Li, Q., et al. (2023). Suppression of microglial Ccl2 reduces neuropathic pain associated with chronic spinal compression. Front Immunol doi: 10.3389/fimmu.2023.1191188 [GLuc-ON™ TMEM119 promoter-reporter clone]
• Chen, H., et al. (2023). PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling. Cell Death Dis doi: 10.1038/s41419-023-05970-2 [GLuc-ON™ NNAT promoter-reporter clone]
• Plasterer, C., et al. (2023). NNAT is a novel mediator of oxidative stress that suppresses ER + breast cancer. Mol Med doi: 10.1186/s10020-023-00673-y [GLuc-ON™ NNAT promoter-reporter clone; OMICSLINK™ NRF1，E2F1 and E2F4 ORF expression clone]
• Yang, X., et al. (2023). Netrin-1 controls inflammation in response to ischemic stroke through altering microglia phenotype. Front Immunol doi: 10.3389/fimmu.2023.1178638 [GLuc-ON™ TMEM119 promoter reporter clone]
• Lee, K-H., et al. (2023). New oncogenic functions of LINE1 retroelement as a ceRNA for tumor suppressive microRNA miR-126 on ENPP5. PLoS One doi: 10.1371/journal.pone.0286814 [Secrete-Pair™ Gaussia Luciferase reporter vector]
• Xiong, X., et al. (2023). E2F1‑mediated RAB34 upregulation accelerates the proliferation and inhibits the cell cycle arrest and apoptosis of acute myeloid leukemia cells. Exp Ther Med doi: 10.3892/etm.2023.12088 [GLuc-ON™ RAB34 promoter-reporter clone]
• Cruz, M.A., et al. (2023). Micronutrient optimization for tissue engineered articular cartilage production of type II collagen. Front Bioeng Biotechnol doi: 10.3389/fbioe.2023.1179332 [Lenti-Pac™ HIV Expression Packaging Kit; GLuc-ON™ COL2A1 promoter-reporter clone]
• Park, J.H., et al. (2023). Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression. Res Sq doi: 10.21203/rs.3.rs-2318750/v1 [GLuc-ON™ promoter-reporter clone]
• Nong, Y., et al. (2023). UBE3A and transsynaptic complex NRXN1-CBLN1-GluD1 in a hypothalamic VMHvl-arcuate feedback circuit regulates aggression. bioRxiv doi: 10.1101/2023.02.28.530462 [GLuc-ON™ promoter-reporter clone]
• Pflug, K., et al. (2023). Transcriptional Induction of NF-kB-Inducing Kinase by E2F4/5 Facilitates Collective Invasion of Glioma Cells. Res Sq doi: 10.21203/rs.3.rs-2622363/v1 [GLuc-ON™ promoter-reporter clone]
• Yang, Y., et al. (2023). Graphene oxide/gallium nanoderivative as a multifunctional modulator of osteoblastogenesis and osteoclastogenesis for the synergistic therapy of implant-related bone infection. Bioact Mater doi: 10.1016/j.bioactmat.2022.07.015 [GLuc-ON™ promoter-reporter clone; Secrete-Pair™ Dual Luminescence Assay Kit]
• Zhang, J., et al. (2023). Naringenin in Si-Ni-San formula inhibits chronic psychological stress-induced breast cancer growth and metastasis by modulating estrogen metabolism through FXR/EST pathway. J Adv Res doi: 10.1016/j.jare.2022.06.006 [GLuc-ON™ promoter-reporter clone; Secrete-Pair™ Dual Luminescence Assay Kit]
• Cui, X., et al. (2023). Hepatocellular carcinoma-derived FOXO1 inhibits tumor progression by suppressing IL-6 secretion from macrophages. Neoplasia doi: 10.1016/j.neo.2023.100900 [GLuc-ON™ promoter-reporter clone; Secrete-Pair™ Gaussia Luciferase Assay Kit]
• Li, X., et al. (2023). Crosstalk between protein kinase C α and transforming growth factor β signaling mediated by Runx2 in intestinal epithelial cells. J Biol Chem doi: 10.1016/j.jbc.2023.103017 [GLuc-ON™ Tgfbr1 promoter-reporter clone]
• Luo, W., et al. (2023). Next-generation sequencing of 500 POI patients identified novel responsible monogenic and oligogenic variants. J Ovarian Res doi: 10.1186/s13048-023-01104-6 [GLuc-ON™ CYP19A1 promoter-reporter clone; HPRM30088-PG04]
• Zhu, L., et al. (2023). A Zeb1/MtCK1 metabolic axis controls osteoclast activation and skeletal remodeling. EMBO J doi: 10.15252/embj.2022111148 [GLuc-ON™ Ckmt1 promoter-reporter clone]
• Yu, C., et al. (2023). Flot2 acts as a novel mediator of podocyte injury in proteinuric kidney disease. Int J Biol Sci doi: 10.7150/ijbs.78945 [GLuc-ON™ Flot2 promoter-reporter clone]
• Togninalli, M., et al. (2023). Machine learning-based classification of dual fluorescence signals reveals muscle stem cell fate transitions in response to regenerative niche factors. NPJ Regen Med doi: 10.1038/s41536-023-00277-4 [MPRM15676-LvPM02]
• Kisler, K., et al. (2023). Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier. Mol Neurodegener doi: 10.1186/s13024-023-00597-5 [GLuc-ON™ promoter-reporter clone]
• Jeon, J., et al. (2023). Blockade of Activin Receptor IIB Protects Arthritis Pathogenesis by Non‐Amplification of Activin A‐ACVR2B‐NOX4 Axis Pathway. Adv Sci (Weinh) doi: 10.1002/advs.202205161 [GLuc-ON™ promoter-reporter clone]
• Wang, R., et al. (2023). SARS-CoV-2 restructures host chromatin architecture. Nat Microbiol doi: 10.1038/s41564-023-01344-8 [GLuc-ON™ IL6 promoter-reporter clone]
• Chen, X., et al. (2023). Interferon regulatory factor 1 (IRF1) inhibits lung endothelial regeneration following inflammation-induced acute lung injury. Clin Sci (Lond) doi: 10.1042/CS20220876 [GLuc-ON™ IRF1 promoter-reporter clone]
• Zheng, Y., et al. (2023). Chronic psychological stress promotes breast cancer pre-metastatic niche formation by mobilizing splenic MDSCs via TAM/CXCL1 signaling. J Exp Clin Cancer Res doi: 10.1186/s13046-023-02696-z [GLuc-ON™ CXCL1 promoter-reporter clone; Luc-Pair™ Duo-Luciferase Assay Kit 2.0]

• Lépine, M., et al. (2022). Parvalbumin interneuron-derived tissue-type plasminogen activator shapes perineuronal net structure. BMC Biol doi: 10.1186/s12915-022-01419-8 [GLuc-ON™  promoter-reporter clone]
• Dong, M., et al. (2022). Milk-derived small extracellular vesicles: nanomaterials to promote bone formation. J Nanobiotechnology doi: 10.1186/s12951-022-01580-w [GLuc-ON™ GJA1 promoter-reporter clone; Secrete-Pair™ Dual Luminescence Assay Kit]
• Jang, J., et al. (2022). Environment-Sensitive Ectodomain Shedding of Epithin/PRSS14 Increases Metastatic Potential of Breast Cancer Cells by Producing CCL2. Mol Cells doi: 10.14348/molcells.2022.2004 [GLuc-ON™  Ccl2 promoter-reporter clone]
• Nguyen, M.T., et al. (2022). The matricellular protein CCN5 induces apoptosis in myofibroblasts through SMAD7-mediated inhibition of NFκB. PLoS One doi: 10.1371/journal.pone.0269735 [GLuc-ON™  promoter-reporter clone; Secrete-Pair™ Gaussia Luminescence Assay Kit]
• Chen, C., et al. (2022). Gemcitabine resistance of pancreatic cancer cells is mediated by IGF1R dependent upregulation of CD44 expression and isoform switching. Cell Death Dis doi: 10.1038/s41419-022-05103-1 [GLuc-ON™ promoter-reporter clone]
• Lee, H-R., et al. (2022). Effect of Aronia Extract on Collagen Synthesis in Human Skin Cell and Dermal Equivalent. Oxid Med Cell Longev doi: 10.1155/2022/4392256 [GLuc-ON™ promoter-reporter clone]
• Gopal, P., et al. (2022). Multivalent state transitions shape the intratumoral composition of small cell lung carcinoma. Sci Adv doi: 10.1126/sciadv.abp8674 [GLuc-ON™ ASCL1, NEUROD1, or YAP1 promoter-reporter clone]
• Jaśkiewicz, M., et al. (2022). The transition from HIF-1 to HIF-2 during prolonged hypoxia results from reactivation of PHDs and HIF1A mRNA instability. Cell Mol Biol Lett doi: 10.1186/s11658-022-00408-7 [GLuc-ON™ promoter-reporter clone]
• Sheikh, A., et al. (2022). Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia. Nat Commun doi: 10.1038/s41467-022-34687-7 [TR104 HNF4 TRE clone for HNF4 signaling pathway]
• Tian, T., et al. (2022). CPT1A promotes anoikis resistance in esophageal squamous cell carcinoma via redox homeostasis. Redox Biol doi: 10.1016/j.redox.2022.102544 [GLuc-ON™ promoter-reporter clone]
• Acharya, S., et al. (2022). Biphasic transcriptional and posttranscriptional regulation of MYB by androgen signaling mediates its growth control in prostate cancer. J Biol Chem doi: 10.1016/j.jbc.2022.102725 [GLuc-ON™ MYBpromoter-reporter clone]
• Lee, J-W., et al. (2022).HeLa Cervical Cancer Cells Are Maintained by Nephronophthisis 3-Associated Primary Cilium Formation via ROS-Induced ERK and HIF-1α Activation under Serum-Deprived Normoxic Condition. Int J Mol Sci doi: 10.3390/ijms232314500 [GLuc-ON™ NPHP3 promoter-reporter clone]
• Lee, J-W., et al. (2022). Nuclear factor (erythroid-derived 2)-like 2 counter-regulates thymosin beta-4 expression and primary cilium formation for HeLa cervical cancer cell survival. Sci Rep doi: 10.1038/s41598-022-24596-6 [GLuc-ON™ TB4X promoter-reporter clone]
• Thevkar-Nagesh, P., et al. (2022). Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation. PLoS One doi: 10.1371/journal.pone.0272986 [GLuc-ON™ Promoter Reporter Clones; Secrete-Pair™ Gaussia Luciferase Assay Kit]
• Ren, Y.Y., et al. (2022). Deregulation of PRDM5 promotes cell proliferation by regulating JAK/STAT signaling pathway through SOCS1 in human lung adenocarcinoma. Cancer Med doi: 10.1002/cam4.5251 [GLuc-ON™ promoter reporter clones]
• Ascenção, K., et al. (2022). Regulation of CyR61 expression and release by 3-mercaptopyruvate sulfurtransferase in colon cancer cells. Redox Biol doi: 10.1016/j.redox.2022.102466 [GLuc-ON™ Promoter Reporter Clones]
• Hu, Z.Y., et al. (2022). CREB1 Transcriptionally Activates LTBR to Promote the NF-κB Pathway and Apoptosis in Lung Epithelial Cells. Comput Math Methods Med doi: 10.1155/2022/9588740 [GLuc-ON™ Promoter Reporter Clones]
• Xiao, X., et al. (2022). Acute sleep deprivation upregulates serotonin 2A receptors in the frontal cortex of mice via the immediate early gene Egr3. Molecular Psychiatry doi: 10.1038/s41380-021-01390-w [GLuc-ON™ Htr1a promoter-reporter clone]
• Li, J., et al. (2022). Auts2 deletion involves in DG hypoplasia and social recognition deficit: The developmental and neural circuit mechanisms. Science Advances doi: 10.1126/sciadv.abk1238 [GLuc-ON™ PTGDS promoter-reporter clone]
• Chen, X., et al. (2022). STAT5A modulates CDYL2/SLC7A6 pathway to inhibit the proliferation and invasion of hepatocellular carcinoma by targeting to mTORC1. Oncogene doi: 10.1038/s41388-022-02273-2 [GLuc-ON™ CDYL2 promoter-reporter clone]
• Zhan, Z., et al. (2022). Oridonin alleviates hyperbilirubinemia through activating LXRα-UGT1A1 axis. Pharmacological Research doi: 10.1016/j.phrs.2022.106188 [GLuc-ON™ UGT1A1 promoter-reporter clone]
• Gomes, A. P., et al. (2022). Altered propionate metabolism contributes to tumour progression and aggressiveness. Nature Metabolism doi: 10.1038/s42255-022-00553-5 [GLuc-ON™ MCEE promoter-reporter clone]
• Xia, Y., et al. (20220. Neuronal C/EBP/AEP pathway shortens life span via selective GABAnergic neuronal degeneration by FOXO repression. Science Advances doi: 10.1126/sciadv.abj8658 [GLuc-ON™ REST, FOXO1 promoter-reporter clones]
• Zhang, J., et al. (2022). Naringenin in Si-Ni-San formula inhibits chronic psychological stress-induced breast cancer growth and metastasis by modulating estrogen metabolism through FXR/EST pathway. Journal of Advanced Research doi: 10.1016/j.jare.2022.06.006 [GLuc-ON™ EST lentiviral promoter-reporter clone]
• Yang, Y., et al. (2022). Graphene oxide/gallium nanoderivative as a multifunctional modulator of osteoblastogenesis and osteoclastogenesis for the synergistic therapy of implant-related bone infection. Bioactive Materials doi: 10.1016/j.bioactmat.2022.07.015 [GLuc-ON™ BMP-2, NFAT-c1 lentiviral promoter-reporter clones]’
• Gielata, M., et al. (2022). Catulin reporter marks a heterogeneous population of invasive breast cancer cells with some demonstrating plasticity and participating in vascular mimicry. Scientific Reports doi: 10.1038/s41598-022-16802-2 [GLuc-ON™ promoter-reporter clone]
• Nguyen, M.T., et al. (2022). The matricellular protein CCN5 induces apoptosis in myofibroblasts through SMAD7-mediated inhibition of NFκB. PLOS ONE doi: 10.1371/journal.pone.0269735 [GLuc-ON™ Smad7 promoter-reporter clone]
• Chen, C., et al. (2022). Gemcitabine resistance of pancreatic cancer cells is mediated by IGF1R dependent upregulation of CD44 expression and isoform switching. Cell Death & Disease doi: 10.1038/s41419-022-05103-1 [GLuc-ON™ CD44 lentiviral promoter-reporter clone]
• McCoy, M.G., et al. (2022) MicroRNA-375 repression of Kruppel-like factor 5 improves angiogenesis in diabetic critical limb ischemia. Angiogenesis doi: 10.1007/s10456-022-09856-3 [GLuc-ON™  promoter-reporter clone]

• Liu, J., et al. (2021). NUPR1 is a critical repressor of ferroptosis. Nature Communications doi: 10.1038/s41467-021-20904-2 [GLuc-ON™ Lcn2 promoter-reporter clone]
• Kuang, F., et al. (2021). MGST1 is a redox-sensitive repressor of ferroptosis in pancreatic cancer cells. Cell Chemical Biology doi: 10.1016/j.chembiol.2021.01.006 [GLuc-ON™ MGST1 promoter-reporter clone]
• Yao, S., et al. (2021). CircRNA ARFGEF1 functions as a ceRNA to promote oncogenic KSHV-encoded viral interferon regulatory factor induction of cell invasion and angiogenesis by upregulating glutaredoxin 3.PLOS Pathogens doi: 10.1371/journal.ppat.1009294 [GLuc-ON™ ARFGEF1 promoter-reporter clone]
• Rippe, C., et al. (2021). NG2/CSPG4, CD146/MCAM and VAP1/AOC3 are regulated by myocardin-related transcription factors in smooth muscle cells. Scientific Reports doi: 10.1038/s41598-021-85335-x [GLuc-ON™ AOC3, MCAM promoter-reporter clones]
• Wang, C., et al. (2021). Elafin promotes tumour metastasis and attenuates the anti-metastatic effects of erlotinib via binding to EGFR in hepatocellular carcinoma. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-021-01904-y [GLuc-ON™ Elatin promoter-reporter clone]
• Li, Y., et al. (2021). PRRT2 gene and protein in human: characteristics, evolution and function. Acta Epileptologica doi: 10.1186/s42494-021-00042-4 [GLuc-ON™ PPT+R2 promoter-reporter clone]
• Sharma, S. ,et al. (2021). Human telomerase is directly regulated by non-telomeric TRF2-G-quadruplex interaction. Cell Reports doi: 10.1016/j.celrep.2021.109154 [GLuc-ON™ PPT+R2 promoter-reporter clone]
• Hu, C., et al. (2021). Ginsenoside Rh2 reduces m6A RNA methylation in cancer via the KIF26B-SRFpositive feedback loop. Journal of Ginseng Research doi: /10.1016/j.jgr.2021.05.004 [GLuc-ON™ KIF26B promoter-reporter clone]
• Rong, Q-x., et al. (2021). GM-CSF mediates immune evasion via upregulation of PD-L1 expression in extranodal natural killer/T cell lymphoma. Molecular Cancer doi: 10.1186/s12943-021-01374-y [GLuc-ON™ PD-L1 promoter-reporter clone]
• Peng, T., et al. (2021). HIF-1αis a negative regulator of interferon regulatoryfactors: Implications for interferon production byhypoxic monocytes. Proceedings of the National Academy of Sciences of the United Sates of America doi: 10.1073/pnas.2106017118 [GLuc-ON™ IRF5 promoter-reporter clone]
• Liu, S., et al. (2021). TRIB3‒GSK-3β interaction promotes lung fibrosis and serves as a potential therapeutic target. Acta Pharmaceutica Sinica B doi: 10.1016/j.apsb.2021.06.017 [GLuc-ON™ GSK-3β promoter-reporter clone]
• Allouche, J., et al. (2021). NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism. Cell doi: 10.1016/j.cell.2021.06.022 [GLuc-ON™ MITF lentiviral promoter-reporter clone]
• Sin, D-P., et al. (2021). A novel mechanism driving poor-prognostic gastric cancer: overexpression of the transcription factor Krüppel-like factor 16 promotes growth and metastasis of gastric cancer through regulating the Notch pathway. Am J Cancer Res. 2021; 11(6): 2717–2735 [GLuc-ON™ MFAP5 promoter-reporter clone]
• Rochford, I., et al. (2021). Evidence for reprogramming of monocytes into reparative alveolar macrophages in vivo by targeting PDE4b, Lung Cellular and Molecular Physiology doi: 10.1152/ajplung.00145.2021 [GLuc-ON™ PDE4b promoter-reporter clone]
• Zhao, M., et al. (2021). Myeloid neddylation targets IRF7 and promotes host innate immunity against RNA viruses. PLOS Pathogens doi: 10.1371/journal.ppat.1009901 [GLuc-ON™ Ifn-α4 promoter-reporter clone]
• Katayoshi, T., et al. (2021). Low-molecular-weight whey proteins promote collagen production in dermal fibroblasts via the TGF-β receptor/Smad pathway. Bioscience, Biotechnology, and Biochemistry doi: 10.1093/bbb/zbab155 [GLuc-ON™ promoter-reporter clone]
• Wu, Z.,, et al. (2021). CDK13-Mediated Cell Cycle Disorder Promotes Tumorigenesis of High HMGA2 Expression Gastric Cancer. Frontiers in Molecular Biosciences doi: 10.3389/fmolb.2021.707295 [GLuc-ON™ CDK13 promoter-reporter clone]
• Chunchacha, P., et al. (2021). Fortilin inhibits p53, halts cardiomyocyte apoptosis, and protects the heart against heart failure. Cell Death Discovery doi: 10.1038/s41420-021-00692-w [GLuc-ON™ p53 promoter-reporter clone]
• Shaoufeng, Y., et al. (2021). SARS-CoV-2 exploits host DGAT and ADRP for efficient replication. Cell Discovery doi: 10.1038/s41421-021-00338-2 [GLuc-ON™ DGAT1, DGAT2 promoter-reporter clones]
• Goedeke, L., et al. (2021). MMAB promotes negative feedback control of cholesterol homeostasis. Nature Communications doi; /10.1038/s41467-021-26787-7 [GLuc-ON™ MVK/MMAB promoter-reporter clone]
• Mukhopadhyay, C., et al. (2021). G3BP1 inhibits Cul3SPOP to amplify AR signaling and promote prostate cancer. Nature Communications doi: 10.1038/s41467-021-27024-x [GLuc-ON™ G3BP1 promoter-reporter clone]
• Vasisth, M., et al. (2021). Scaling concepts in ‘omics: Nuclear lamin-B scales with tumor growth and often predicts poor prognosis, unlike fibrosis. Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.2112940118 [GLuc-ON™ LaminB1 promoter-reporter clone]

• McCutcheon, S., et al. (2020). Apoptotic osteocytes induce RANKL production in bystanders via purinergic signaling and activation of pannexin channels. Journal of Bone and Mineral Research doi: 10.1002/jbmr.3954 [GLuc-ON™ lentiviral promoter-reporter clone]
• Han, Y., et al. (2020). Remodeling of Zn2+ Homeostasis Upon Differentiation of Mammary Epithelial Cells. Metallomics doi: 10.1039/C9MT00301K [GLuc-ON™ CSN2 promoter-reporter clone]
• Zhou, J-p., et al. (2020). Obesity-Induced Upregulation of ZBTB7A Promotes LipidAccumulation through SREBP1. Biomed Research International doi: 10.1155/2020/4087928 [GLuc-ON™ SREBP1  promoter-reporter clone]
• Tai, F., et al. (2020). Enhanced JunD/RSK3 signalling due to loss of BRD4/FOXD3/miR-548d-3p axis determines BET inhibition resistance. Nature Communications doi: 10.1038/s41467-019-14083-4 [GLuc-ON™ wild type and mutant RPS6KA2 promoter-reporter clones]
• Pandey, P.R., et al. (2020). circSamd4 represses myogenic transcriptional activity of PUR proteins. Nucleic Acids Research doi: 10.1093/nar/gkaa035 [GLuc-ON™ MHC promoter-reporter clone]
• Zhu, B., et al. (2020). Antagonistic relationship between the unfolded protein response and myocardin‐driven transcription in smooth muscle. Journal of Cellular Physiology doi: 10.1002/jcp.29637 [GLuc-ON™ MSRB3 promoter-reporter clone]
• Zhang, L., et al. (2020). Stat3 activation induces insulin resistance via a muscle-specific E3 ubiquitin ligase Fbxo40. American Journal of Physiology-Endocrinology and Metabolism doi: 10.1152/ajpendo.00480.2019. [GLuc-ON™ Fbxo40 promoter-reporter clone]
• Huang, R., et al. (2020). CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling. Cell Death & Disease doi: 10.1038/s41419-020-2435-y. [GLuc-ON™ CCL5 promoter-reporter clone]
• Marneros, A.G. (2020). AP-2β/KCTD1 Control Distal Nephron Differentiation and Protect against Renal Fibrosis. Developmental Cell doi: 10.1016/j.devcel.2020.05.026  [GLuc-ON™ KCTD1 promoter-reporter clone]
• Makino, E., et al. (2020). Targeting Rad51 as a strategy for the treatment of melanoma cells resistant to MAPK pathway inhibition. Cell Death & Disease doi: 10.1038/s41419-020-2702-y  [GLuc-ON™ RAD52 promoter-reporter clone]
• Donato, G., et al. (2020). Hypoxia Triggers the Intravasation of Clustered Circulating Tumor Cells. Cell Reports doi: 10.1016/j.celrep.2020.108105  [GLuc-ON™ HIF1α promoter-reporter clone]
• Hou, J., et al. (2020). PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis. Nature Cell Biology doi: 10.1038/s41556-020-0575-z   [GLuc-ON™ GSDMC promoter-reporter clone]
• Chen, -Y., et al. (2020). Lysine demethylase 2A expression in cancer-associated fibroblasts promotes breast tumour growth. British ournal of Cancer doi: 10.1038/s41416-020-01112-z [GLuc-ON™ KDM2A promoter-reporter clone]
• Le, B.C., et al. (2020). TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment. Cell Reports doi: 10.1016/j.celrep.2020.108221 [GLuc-ON™ promoter-reporter clones]
• Jiang, H., et al. (2020). Jagged1-Notch1-deployed tumor perivascular niche promotes breast cancer stem cell phenotype through Zeb1. Nature Communications doi: 10.1038/s41467-020-18860-4 [GLuc-ON™ Zeb1 promoter-reporter clone]
• Zarei, M., et al. (2020). MITF is a driver oncogene and potential therapeutic target in kidney angiomyolipoma tumors through transcriptional regulation of CYR61. Oncogene doi: 10.1038/s41388-020-01504-8 [GLuc-ON™ CYR61, ID2  promoter-reporter clones]
• Orzechowska, E.J., et al. (2020). Interplay among p21Waf1/Cip1, MUSASHI-1 and Krüppel-like factor 4 in activation of Bmi1-CreER reserve intestinal stem cells after gamma radiation-induced injury. Scientific Reports doi: 10.1038/s41598-020-75171-w [GLuc-ON™Msi1 promoter-reporter clone]
• Byun, J-k., et al. (2020). Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity .Molecular Cell doi: 10.1016/j.molcel.2020.10.015  [GLuc-ON™ PD-L1, Fas promoter-reporter clones]
• Singh, S.R., et al. (2020). A high-throughput screening identifies ZNF418 as a novel regulator of the ubiquitin-proteasome system and autophagy-lysosomal pathway. Autophagy doi: 10.1080/15548627.2020.1856493 [GLuc-ON™ mouse Fyco1p promoter-reporter clone]

• Wang, H-B., et al. (2019). Down-regulated expression of LINC00518 prevents epithelial cell growth and metastasis in breast cancer through the inhibition of CDX2 methylation and activation of the Wnt signaling pathway. Biochimica et Biophysica Acta (BBA) – Molecular Basis of Disease doi: 10.1016/j.bbadis.2019.01.003  [GLuc-ON™ LINC00518 promoter-reporter clone]
• Floris, A., et al. (2019). Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-018-1013-y  [GLuc-ON™ STARD10 promoter-reporter clone]
• Arumugam, A., et al. (2019). Silencing growth hormone receptor inhibits estrogen receptor negative breast cancer through ATP-binding cassette sub-family G member 2. Experimental and Molecular Medicine doi: 10.1038/s12276-018-0197-8  [GLuc-ON™ ABCG2 promoter-reporter clone]
• Lakshmipathi, J., et al. (2019). Identification of NFAT5 as a transcriptional regulator of the EDN1gene in collecting duct. American Journal of Renal Physiology doi: 10.1152/ajprenal.00509.2018  [GLuc-ON™ promoter-reporter clone]
• Schwatrz, D.M., et al. (2019). Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology. Immunity doi: 10.1016/j.immuni.2018.12.014  [GLuc-ON™ promoter-reporter clones]
• Ting, C-H, et al. (2019). FOSB–PCDHB13 Axis Disrupts the Microtubule Network in Non-Small Cell Lung Cancer. Cancers doi: 10.3390/cancers11010107 [GLuc-ON™ PCDHB13 promoter-reporter clone]
• Qin, Y., et al. (2019). ZEB1 promotes tumorigenesis and metastasis in hepatocellular carcinoma by regulating the expression of vimentin. Molecular Medicine Reports doi: 10.3892/mmr.2019.9866 [GLuc-ON™ promoter-reporter clone]
• Beug, S.T., et al. (2019). The transcription factor SP3 drives TNF-α expression in response to Smac mimetics. Science Signaling doi: 10.1126/scisignal.aat9563 [GLuc-ON™ TNF-α promoter-reporter clone]
• Lee, B.B., et al. (2019). Metformin and tenovin‐6 synergistically induces apoptosis  through LKB1‐independent SIRT1 down‐regulation in non‐ small cell lung cancer cells. Journal of Cellular and Molecular Medicine doi: 10.1111/jcmm.14194 [GLuc-ON™ SIRT1 promoter-reporter clone]
• Wen, Q., et al. (2019). FoxO3a inhibiting expression of EPS8 to prevent progression of NSCLC: A new negative loop of EGFR signaling. bRioMedicine doi: 10.1016/j.ebiom.2019.01.053 [GLuc-ON™ EPS8 promoter-reporter clone]
• Kang, P.J., et al. (2019). Glycine decarboxylase regulates the maintenance and induction of pluripotency via metabolic control. Metabolic Engineering doi: 10.1016/j.ymben.2019.02.003 [GLuc-ON™ GLDC promoter-reporter clone]
• Candelas, M., et al. (2019). Cav3.2 T-type calcium channels shape electrical firing in mouse Lamina II neurons. Scientific Reports doi: 10.1038/s41598-019-39703-3 [GLuc-ON™ Cav3.2 promoter-reporter clone]
• METHOD OF PRODUCING RENAL CELLS FROM DIFFERENTIATED CELLS. United States Patent Application 20190071646 [GLuc-ON™ CDH16 promoter-reporter clone]
• Namachivayam, K., et al. (2019). All-Trans Retinoic Acid Induces TGF-β2 in Intestinal Epithelial Cells via RhoA- and p38α MAPK-Mediated Activation of the Transcription Factor ATF2. PLOS ONE doi: 10.1371/journal.pone.0134003 [GLuc-ON™ TGF-β2 promoter-reporter clone]
• Aalipour, A., et al. (2019). Engineered immune cells as highly sensitive cancer diagnostics. Nature Biotechnology doi: 10.1038/s41587-019-0064-8 [GLuc-ON™ pArg1 promoter-reporter clone]
• Dussold, C., et al. (2019). DMP1 prevents osteocyte alterations, FGF23 elevation and left ventricular hypertrophy in mice with chronic kidney disease. Bone Research doi: 10.1038/s41413-019-0051-1 [GLuc-ON™ Fgf23 promoter-reporter clone]
• Sun, L., et al. (2019). Lnc‐NA inhibits proliferation and metastasis in endometrioid endometrial carcinoma through regulation of NR4A1. Journal of Cellular and Molecular Medicine doi: 10.1111/jcmm.14345 [GLuc-ON™ NRF4A1 promoter-reporter clone]
• Lee, J.W., et al. (2019). Thymosin β-4 is a novel regulator for primary cilium formation by nephronophthisis 3 in HeLa human cervical cancer cells. Scientific Reports doi: 10.1038/s41598-019-43235-1  [GLuc-ON™ NPHP3, Tβ4 promoter-reporter clones]
• Chen, T-Y., et al. (2019). Determination of Pyruvate Metabolic Fates Modulates Head and Neck Tumorigenesis. Neoplasia doi: 10.1016/j.neo.2019.04.007 [GLuc-ON™ LDHA, PDHA1 promoter-reporter clones]
• Lee, C-M., et al. (2019). Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3. Life Science Alliance doi: 10.26508/lsa.201900350 [GLuc-ON™ SMAD7 promoter-reporter clone]
• Muromoto, R., et al. (2019). IκB-ζ Expression Requires Both TYK2/STAT3 Activity and IL-17–Regulated mRNA Stabilization. ImmunoHorizons  doi: doi.org/10.4049/immunohorizons.1900023 [GLuc-ON™ NFKBIZ promoter-reporter clone]
• Liu, H-B., et al. (2019). RNA-Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation. Advanced Science doi: 10.1002/advs.201900295 [GLuc-ON™ IGF2 L3  promoter-reporter clone]
• Han, F., et al.(2019). Dopamine D2 receptor modulates Wnt expression and control of cell proliferation. Scientific Reports doi: 10.1038/s41598-019-52528-4 [GLuc-ON™ WNT3A  promoter-reporter clone]
• Wang, S., et al. (2019). XIAOPI Formula Inhibits Breast Cancer Stem Cells via Suppressing Tumor-Associated Macrophages/C-X-C Motif Chemokine Ligand 1 Pathway. Frontiers in Pharmacology doi: 10.3389/fphar.2019.01371 [GLuc-ON™ CXCL1 promoter-reporter clone]
• Crochemore, C., et al. (2019). CSB promoter downregulation via histone H3 hypoacetylation is an early determinant of replicative senescence. Nature Communications doi: 10.1038/s41467-019-13314-y [GLuc-ON™ CDKN1A promoter-reporter clone]
• Yu, J-m,., et al. (2010). TRIB3 supports breast cancer stemness by suppressing FOXO1 degradation and enhancing SOX2 transcription. Mature Communications doi: 10.1038/s41467-019-13700-6 [GLuc-ON™ FOXO1, SOX2 promoter-reporter clones]
• Rivera-Soto, R., et al. (2019). Kaposi’s Sarcoma-associated Herpesvirus Viral Interleukin 6 Signaling Upregulates Integrin Beta 3 Levels and is Dependent on STAT3. Journal of Virology doi: 10.1128/JVI.01384-19 [GLuc-ON™ ITGB3 promoter-reporter clone]
• Liu, Y-n., e tla. (2019). Acquired resistance to EGFR tyrosine kinase inhibitors is mediated by the reactivation of STC2/JUN/AXL signaling in lung cancer. International Journal of Cancer doi: 10.1002/ijc.32487 [GLuc-ON™ promoter-reporter clone]
• Yang, Y.M., et al. (2019). Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis. Science Translational Medicine doi: 10.1126/scitranslmed.aat9284 [GLuc-ON™ NOTCH1 promoter-reporter clones]
• Jiang, L., et al. (2019). Ivermectin reverses the drug resistance in cancer cells through EGFR/ERK/Akt/NF-κB pathway. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-019-1251-7 [GLuc-ON™ ABCB1 promoter-reporter clone]
• Xiao, X-G., et al. (2019). miR-665 expression predicts poor survival and promotes tumor metastasis by targeting NR4A3 in breast cancer. Cell Death & Disease doi: 10.1038/s41419-019-1705-z [GLuc-ON™ β-catenin promoter-reporter clone]
• AbuSamra, D.B., et al .(2019). Galectin-3 initiates epithelial-stromal paracrine signaling to shape the proteolytic microenvironment during corneal repair. Science Signaling doi: 10.1126/scisignal.aaw7095 [GLuc-ON™ MMP9 lentiviral promoter-reporter clone]
• Xu, C., et al. (2019). A novel ZRS variant causes preaxial polydactyly type I by increased sonic hedgehog expression in the developing limb bud. Genetics in Medicine doi: 10.1038/s41436-019-0626-7 [GLuc-ON™ SHH promoter-reporter clone]

• Smith, S.R., et al. (2018). The phosphatase PPM1A controls monocyte-to-macrophage differentiation. Scientific Reports. DOI: 10.1038/s41598-017-18832-7  [GLuc-ON™ PPM1A lentiviral promoter-reporter clone]
• Bueno, M., et al. (2018). ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis. Aging Cell. DOI: 10.1111/acel.12720  [GLuc-ON™ PINK1  promoter-reporter clone]
• Wang, J., et al. (2018). Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastoma. Oncotarget. DOI: 10.18632/oncotarget.23152  [GLuc-ON™ TTK promoter-reporter clone]
• Mu, N., et al. (2018). PRL- 3 is a potential glioblastoma  prognostic marker and  promotes glioblastoma progression  by  enhancing  MMP7  through the ERK and JNK pathways. Theranostics. DOI: 10.7150/ thno .22699   [GLuc-ON™ MMP7 promoter-reporter clone]
• Li, C-W., et al. (2018). Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1. Cancer Cell. DOI: 10.1016/j.ccell.2018.01.009 [GLuc-ON™ B3GNT3 promoter-reporter clone]
• Tripathi, R., et al. (2018). Abl and Arg mediate cysteine cathepsin secretion to facilitate melanoma invasion and metastasis. Science Signaling. DOI: 10.1126/scisignal.aao0422 [GLuc-ON™ Human cathepsin L, cathepsin B, Sp1, and Ets1 promoter-reporter clones]
• Armelloni, S., et al. (2018). NeuroD Expression in Podocytes and Interrelationships with Nephrin at Both Nuclear and Cytoplasmic Sites. Cellular Physiology and Biochemistry. DOI: 10.1159/000488818 [GLuc-ON™ Nephrin, Kirrel2 promoter-reporter clones]
• Liu, D., et al. (2018). Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target. Science Translational Medicine. DOI: 10.1126/scitranslmed.aap9840 [GLuc-ON™ SQLE promoter-reporter clone]
• Yang, T., et al.  (2018). Brain ischemic preconditioning protects against ischemic injury and preserves the blood-brain barrier via oxidative signaling and Nrf2 activation. Redox Biology. DOI: 10.1016/j.redox.2018.05.001 [GLuc-ON™ Nrf2 lentiviral promoter-reporter clone]
• Chen, Y-C., et al. (2018). ATOH1/RFX1/RFX3 transcription factors facilitate the differentiation and characterisation of inner ear hair cell-like cells from patient-specific induced pluripotent stem cells harbouring A8344G mutation of mitochondrial DNA. Cell Death & Disease. DOI: 10.1038/s41419-018-0488-y2 [GLuc-ON™ MYO7A lentiviral promoter-reporter clone]
• Taha, A.S., et al. (2018). Tu1958 – Aspirin, NSAIDs, and Dysplastic Colonic Polyps – Lessons from Bowel Cancer Screening. Gastroenterology. DOI: 10.1016/S0016-5085(18)33561-3 [GLuc-ON™ COX-2  promoter-reporter clone]
• Jia, Y., et al. (2018). The novel KLF4/PLAC8 signaling pathway regulates lung cancer growth. Cell Death & Disease. DOI: 10.1038/s41419-018-0580-3 [GLuc-ON™ PLAC8 wild type and mutant promoter-reporter clones]
• Collmann, F.M., et al. (2018). Imaging Reporter Strategy to Monitor Gene Activation of Microglia Polarisation States under Stimulation. Journal of Neuroimmune Pharmacology. DOI: 10.1007/s11481-018-9789-2 [GLuc-ON™ Ym1, Fcgr3 promoter-reporter clones]
• Biddlestone, J., et al. (2018). SINHCAF/FAM60A and SIN3A specifically repress HIF 2α expression. Biochemical Journal. DOI: 10.1042/BCJ20170945 [GLuc-ON™ HIF 2α promoter-reporter clone]
• Xiang, S., et al. (2018).  Crosstalk of NF-κB/P65 and LncRNA HOTAIR-Mediated Repression of MUC1 Expression Contribute to Synergistic Inhibition of Castration-Resistant Prostate Cancer by Polyphyllin 1-Enzalutamide Combination Treatment. Cellular Physiology and Biochemistry. DOI: 10.1159/000490028 [GLuc-ON™ HOTAIR, MUC1 promoter-reporter clones]
• Hildebrandt, S., et al,. (2018). Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo. Scientific Reports. DOI: 10.1038/s41598-018-26300-z [GLuc-ON™ Wnt16 promoter-reporter clone]
• Ye, D-J., et al. (2018). Discovery of ezrin expression as a potential biomarker for chemically induced ocular irritation using human corneal epithelium cell line and a reconstructed human cornea-like epithelium model. Toxicological Sciences. DOI: 10.1093/toxsci/kfy134 [GLuc-ON™ EZR promoter-reporter clone]
• Lu, Y., et al. (2018). Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors. Cancer Cell. DOI: 10.1016/j.ccell.2018.05.004 [GLuc-ON™ Traf6 promoter-reporter clone]
• Al-Hattab, D.S., et al. (2018). Scleraxis regulates Twist1 and Snai1 expression in the epithelial-to-mesenchymal transition. American Journal of Physiology-Heart and Circulatory Physiology. DOI: 10.1152/ajpheart.00092.2018 [GLuc-ON™ Twist promoter-reporter clone]
• Subramani, R., et al. (2018). FOXC1 plays a crucial role in the growth of pancreatic cancer. Oncogenesis. DOI: 10.1038/s41389-018-0061-7 [GLuc-ON™ FOXC1 promoter-reporter clone]

• Druzd, D., et al. (2017). Lymphocyte Circadian Clocks Control Lymph Node Trafficking and Adaptive Immune Responses. Immunity. DOI: 10.1016/j.immuni.2016.12.011  [GLuc-ON™ S1pr1 promoter-reporter clone]
• Alvarado, A.G., et al. (2017). Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression. Cell Stem Cell. DOI: 10.1016/j.stem.2016.12.001 [GLuc-ON™ SOX2, OCT4, and NANOG promoter-reporter clones]
• Tang, Q., et al. (2017). Emodin Increases Expression of Insulin-Like Growth Factor Binding Protein 1 through Activation of MEK/ERK/AMPKα and Interaction of PPARγ and Sp1 in Lung Cancer. Cellular Physiology and Biochemistry. DOI: 10.1159/000456281. [GLuc-ON™ IGFBP1 promoter-reporter clone]
• Wang, X., et al. (2017). Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF. Nature Communications. DOI: 10.1038/ncomms14091 [GLuc-ON™ LGR5 promoter-reporter clone]
• Feng, W., et al. (2017). SOX10 induced Nestin expression regulates cancer stem cell properties of TNBC cells. Biochemical and Biophysical Research Communications. DOI: 10.1016/j.bbrc.2017.02.014 [NES promoter-reporter clone]
• Wu, D.W., et al. (2017). The YAP1/SIX2 axis is required for DDX3 -mediated  tumor aggressiveness and cetuximab resistance in  KRAS -wild -type colorectal cancer. Theranostics. DOI: 10.7150/ thno .18175 [GLuc-ON™ YAP1 and SIX2 promoter-reporter clones]
• Lim, J.P., et al. (2017).  YBX1 gene silencing inhibits migratory and invasive potential via CORO1C in breast cancer in vitro. BMC Cancer. DOI: 10.1186/s12885-017-3187-7 [GLuc-ON™ CORO1C promoter-reporter clone]
• Cho, Y.S., et al. (2017).  COMPOSITIONS COMPRISING A MITOFUSIN INHIBITOR FOR PROMOTING CELL REPROGRAMMING AND A USE THEREOF United States Patent Application 20170051254 [GLuc-ON™ Mfn1 promoter-reporter clone]
• Sun, J., et al. (2017). HMGA2 regulates CD44 expression to promote gastric  cancer cell motility and sphere formation. Am J Cancer Res 2017;7(2) :260-274 [GLuc-ON™ c-Myc promoter-reporter clone]
• Mondello, P., et al. (2017). Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265 mutations. JC Insight. DOI: DOI.org/10.1172 [GLuc-ON™ MyD88 promoter-reporter clone]
• Shen, Z.H., et al. (2017). HOXA10 promotes nasopharyngeal carcinoma cell proliferation and invasion via inducing  the expression of  ZIC2. European  Review for  Medical and Pharmacological Sciences 2017; 21: 945-952 [GLuc-ON™ ZIC2 promoter-reporter clone]
• Shen, C.J., et al. (2017). MMP1 expression is activated by Slug and enhances multi-drug resistance (MDR) in breast cancer. PLoS ONE. DOI: 10.1371/journal.pone.0174487 [GLuc-ON™ MMP1 promoter-reporter clone]
• Wu, J.J., et al. (2017). Interplay of DNA methyltransferase 1 and EZH2 through inactivation of Stat3 contributes to β-elemene-inhibited growth of nasopharyngeal carcinoma cells. Scientific eports. DOI: 10.1038/s41598-017-00626-6 [GLuc-ON™ EZH2 promoter-reporter clone]
• Qu, L.P., et al. (2017). CDH17 is a downstream effector of  HOXA13 in modulating the Wnt/ β -catenin signaling pathway in gastric cancer. European  Review for  Medical and  Pharmacological  Sciences 2017; 21: 1234-1241 [GLuc-ON™ CDH17  promoter-reporter clone]
• Morel, A. P., et al. (2017). A stemness-related ZEB1–MSRB3 axis governs cellular pliancy and breast cancer genome stability. Nature Medicine. DOI: 10.1038/nm.4323 [GLuc-ON™ MSRB3 promoter-reporter clone]
• Liu, J., et al. (2017). DDA1 is induced by NR2F6 in ovarian cancer  and predicts poor survival outcome. European  Review for  Medical and  Pharmacological  Sciences 2017; 21: 1206 -1213 [GLuc-ON™ DDA1 promoter-reporter clone]
• Wang, L., et al. (2017). FSCN1 is upregulated by SNAI2 and promotes epithelial to mesenchymal transition in head and necksquamous cell carcinoma. Cell Biology International. DOI: 10.1002/cbin.10786 [GLuc-ON™ FSCN1 promoter-reporter clone]
• Larson, M.E., et al. (2017). Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits. Proc. Natl. Acad. Sci. U.S.A.. DOI:     10.1073/pnas.1704698114 [GLuc-ON™ SYN2 promoter-reporter clone]
• Azeem, W., et al. (2017). An androgen response element driven reporter assay for the detection of androgen receptor activity in prostate cells. PLoS ONE. DOI: 10.1371/journal.pone.0177861 [ARE promoter-reporter clone]
• Li, D., et al. (2017). Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity. Free Radical Biology and Medicine. DOI: 10.1016/j.freeradbiomed.2017.06.002 [GLuc-ON™ PPARα promoter-reporter clone]
• TianJ., et al. (2017). E2F8 confers cisplatn resistance to ER+ breast cancer cells via transcriptionally activating MASTL. Biomedicine & Pharmacotherapy. DOI: 10.1016/j.biopha.2017.05.118 [MASTL promoter-reporter clone]
• Xie, Q. nd Cao, X. (2017). Mitochondrial transcription factor A protects human retinal endothelial cell injury induced by hypoxia. Tropical Journal of Pharmaceutic al Research . DOI: 10.4314/tjpr.v16i6.8 [NF-κB Promoter-Reporter clone]
• Yang, B., et al. (2017). Yes‐associated protein 1 promotes the differentiation and mineralization of cementoblast. Journal of Cellular Physiology. DOI: 10.1002/jcp.26089 [DSPP Promoter-Reporter clone]
• Erdmann, K., et al. (2017). Induction of alpha-methylacyl-CoA racemase by miR-138 via up-regulation of β-catenin in prostate cancer cells. Journal of Cancer Research and Clinical Oncology. DOI:10.1038/nrg.2016.134 [GLuc-ON™ CTNNB1 Promoter-Reporter clone]
• Thiagarajan, P.S., et al. (2017). STAT3 activation by leptin receptor is essential for TNBC stem cell maintenance. Endocrine-Related Cancer. DOI: 10.1530/ERC-16-0349 [GLuc-ON™ NANOG, SOX2, and OCT4 Promoter-Reporter clones]
• Madar-Shapiro, L., et al. (2017). Predicting the Risk to Develop Preeclampsia in the First Trimester Combining Promoter Variant -98A/C of LGALS13 (Placental Protein 13), Black Ethnicity, Previous Preeclampsia, Obesity, and Maternal Age. Fetal Diagnosis and Therapy. DOI: 10.1159/000477933 [GLuc-ON™ LGALS13 Promoter-Reporter clone]
• Huang, L.S., et al. (2017). Lysocardiolipin acyltransferase regulates TGF-β mediated lung fibroblast differentiation. Free Radical Biology and Medicine. DOI: 10.1016/j.freeradbiomed.2017.07.023 [GLuc-ON™ LYCAT Promoter-Reporter clone]
• McCutcheon, S., et al. (2017). A multiscale fluidic device for the study of dendrite-mediated cell to cell communication. Biomedical Microdevices. DOI: 10.1007/s10544-017-0212-1 [GLuc-ON™ mouse Tnfsf11 lentiviral promoter-reporter clone]
• Correa, D., et al. (2017). Non-destructive/non-invasive imaging evaluation of cellular differentiation progression during in vitro MSC-derived chondrogenesis. Tissue Engineering. DOI: 10.1089/ten.TEA.2017.0125 [GLuc-ON™ Sox9 and Aggrecan lentiviral promoter-reporter clones]
• Jiang, Z., et al. (2017). Ribosome profiling reveals translational regulation of mammalian cells in response to hypoxic stress. BMC Genomics. DOI: 10.1186/s12864-017-3996-8 [GLuc-ON™ uORFpromoter-reporter clone]
• Zhang, Q., et al. (2017). Repression of ESR1 transcription by MYOD potentiates letrozle-resistance in ERα-positive breast cancer cells. Biochemical and Biophysical Research Communications. DOI: 10.1016/j.bbrc.2017.08.082 [GLuc-ON™ ESR1 promoter-reporter clone]
• Zheng, F., et al. (2017). The enhancement of combination of berberne and metformn in inhibition of DNMT1 gene expression through interplay of SP1 and PDPK1. Journal of Cellular and Mlecular Medicine. DOI: 10.1111/jcmm.13347 [GLuc-ON™ DNMT1 promoter-reporter clone]
• Zhu, M. (2017). Hyperlipidemia-induced  MicroRNA- 155-5p improves  β -cell Function by  targeting  Mafb. Ph.D. Thesis, Universität München [GLuc-ON™ mouse IL6 promoter-reporter clone]
• Yao, J., et al. (2017). Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. Journal of Cell Biology. DOI: 10.1083/jcb.201612122 [GLuc-ON™ albumin promoter-reporter clone]
• Yang, W.W., et al. (2017). Epiregulin Promotes Lung Metastasis of Salivary  Adenoid Cystic Carcinoma. Theranostics. DOI: 10.7150/ thno.19712  [GLuc-ON™ CDH1 promoter-reporter clone]
• Yoshimatsu, G., et al. (2017). Pancreatic Beta Cell-derived IP-10/CXCL10 Isletokine Mediates Early Loss of Graft Function in Islet Cell Transplantation. Diabetes. DOI: 10.2337/db17-0578 [GLuc-ON™ mouse IP-10 promoter-reporter clone]
• Zhou, Y.F., et al. (2017). Tumor necrosis factor-α and interleukin-6 suppress microRNA-1275 transcription in human adipocytes through nuclear factor-κB. Molecular Medicine Reports. DOI: 10.3892/mmr.2017.7392   [GLuc-ON™ miR-1275 promoter-reporter clone]
• Chen, G., et al. (2017). GENERATING GABAergic NEURONS IN BRAINS.  United States Patent Application 20170239373   [GLuc-ON™ LMTK2 promoter-reporter clone]
• Dey, I. and Bradbury, N.A. (2017). Activation of TPA-response element present in human Lemur Tyrosine Kinase 2 (lmtk2) gene increases its expression. Biochemistry and Biophysics Reports. DOI: 10.1016/j.bbrep.2017.09.006 [GLuc-ON™ hng2 promoter-reporter clone]
• Dey, I. and Bradbury, N.A. (2017). Activation of TPA-response element present in human Lemur Tyrosine Kinase 2 (lmtk2) gene increases its expression. Biochemistry and Biophysics Reports. DOI: 10.1016/j.bbrep.2017.09.006 [GLuc-ON™ LMTK2 promoter-reporter clone]
• Wang, J.X., et al. (2017). GLI2 induces PDGFRB expression and  modulates cancer stem cell properties of gastric cancer. European  Review for  Medical and  Pharmacological  Sciences 2017; 21: 3857-3865 [GLuc-ON™ PDGFRB  promoter-reporter clone]
• Zhang, H., et al. (2017). Inducible ATF3–NFAT axis aggravates podocyte injury. Journal of Molecular Medicine. DOI: 10.1007/s00109-017-1601-x [GLuc-ON™ NRATC1 promoter-reporter clone]
• Xiao, Q., et al. (2017). Activation of ERK and Mutual Regulation of Stat3 and SP1 Contribute to Inhibition of PDK1 Expression by Atractylenolide-1 in Human Lung Cancer Cells. Cellular Physiology and Biochemistry. DOI: 10.1159/000484387 [GLuc-ON™ promoter-reporter clone]
• Tang, Q., et al. (2017). Combination of Solamargine and Metformin Strengthens IGFBP1 Gene Expression Through Inactivation of Stat3 and Reciprocal Interaction Between FOXO3a and SP1. Cellular Physiology and Biochemistry. DOI: 10.1159/000484383 [GLuc-ON™ promoter-reporter clone]
• Hung, S., and Hsu, H. (2017). METHOD FOR INHIBITING SURVIVAL, TUMORIGENESIS AND METASTASIS OF CANCER CELLS AND/OR CANCER STEM CELLS. United States Patent Application 20170304386 [GLuc-ON™ Col17-A1 promoter-reporter clone]
• Singh, B.K., et al. (2017). Anti-melanogenic effect of Prunus davidiana extract in melan-a melanocyte through regulation of OCA-2, TRP-1 and tyrosinase. Korean Journal of Chemical Engineering. DOI: 10.1007/s11814-017-0241-8 [GLuc-ON™  promoter-reporter clone]
• Huang, L., et al. (2017). miR19b-3p promotes the growth and metastasis of colorectal cancer via directly targeting ITGB8. Am J Cancer Res 2017;7(10):1996-2008 [GLuc-ON™  FOXL2 wild type and mutant promoter-reporter clones]
• Xu, H.Y., et al. (2017). Metformn reduces SATB2-mediated osteosarcoma stem cell-like phenotype and tumor growth via inhibition of N-cadherin/NF- k B signaling. European Review for Medical and Pharmacological Sciences 2017; 21: 4516-4528 [GLuc-ON™  N-caderin promoter-reporter clone]
• Wilkinson, D.C., et al. (2017). Development of a Three‐Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling. Stem Cells Translational Medicine. DOI: 10.5966/sctm.2016-0192 [GLuc-ON™  ACTA2 promoter-reporter clone]
• Xiang, S.T., et al. (2017). HOTAIR-mediated reciprocal regulation of EZH2 and DNMT1 contribute to polyphyllin I-inhibited growth of castration-resistant prostate cancer cells in vitro and in vivo. Biochimica et Biophysica Acta (BBA) – General Subjects. DOI: 10.1016/j.bbagen.2017.12.001 [GLuc-ON™  promoter-reporter clones]
• Jiang, N., et al. (2017). YAP1 regulates prostate cancer stem cell-like characteristics to promote castration resistant growth. Oncotarget. DOI: 10.18632/oncotarget.23014 [GLuc-ON™  YAP1 promoter-reporter clone]
• Wang, N., et al. (2017). Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde. Oncotarget. DOI: 10.18632/oncotarget.22406 [GLuc-ON™  human β-catenin promoter-reporter clone]

• Liao, BM., et al. (2016) Flavin-Containing Monooxygenase 3 Reduces Endoplasmic Reticulum Stress in Lipid-Treated Hepatocytes. Molecular Endocrinology,DOI: http://dx.doi.org/10.1210/me.2015-1217. [FMO3 promoter clone and secreted pair luciferase kit]
• Dougherty, E.J., et al. (2016). Mineralocorticoid Receptor (MR) Trans-Activation of Inflammatory AP-1 Signaling: Dependence on DNA Sequence, MR Conformation, and AP-1 Family Member Expression. The Journal of Biological Chemistry. DOI: 10.1074/jbc.M116.732248 [human  XIRP1 promoter clone]
• Li, L., et al. (2016). Inhibition of EZH2 via activation of SAPK/JNK and reduction of p65 and DNMT1 as a novel mechanism in inhibition of human lung cancer cells by polyphyllin I. Journal of Experimental & Clinical Cancer Research. DOI: 10.1186/s13046-016-0388-x [EZH2 promoter-reporter clone]
• Mao, C., et al. (2016). Double-edged-sword effect of IL-1β on the osteogenesis of periodontal ligament stem cells via crosstalk between the NF-κB, MAPK and BMP/Smad signaling pathways. Cell Death and Disease. DOI: 10.1038/cddis.2016.204 [BMP2 promoter-reporter clone]
• Gujar, R., et al. (2016). c-Src Suppresses Dendritic Cell Antitumor Activity via T Cell Ig and Mucin Protein-3 Receptor. The Journal of Immunology. DOI: 10.4049/​jimmunol.1600104  [mouse wild tyoe and mutant HAVCR2 promoter-reporter clones]
• Chen, J., et al. (2016). Vitamin D Deficiency Promotes Liver Tumor Growth in Transforming Growth Factor-β/Smad3-Deficient Mice Through Wnt and Toll-like Receptor 7 Pathway Modulation. Scientific Reports. DOI: 10.1038/srep30217 [TLR7 Promoter-reporter clone]
• Nakajima, S., et al. (2016). Fungal-derived neoechinulin B as a novel antagonist of liver X receptor, identified by chemical genetics using hepatitis C virus cell culture system . Journal of Virology. DOI: 10.1128/JVI.00856-16 [SCD-1 promoter reporter clone]
• Zhu, L., et al. (2016). Knockdown of Sall4 inhibits intrahepatic cholangiocarcinoma cell migration and invasion in ICC-9810 cells. OncoTargets and Therapy. DOI: 10.2147/OTT.S107214 [PTEN and Bmi-1 promoter clones]
• Rehman, M., et al. (2016). PlexinD1 Is a Novel Transcriptional Target and Effector of Notch Signaling in Cancer Cells. PLoS ONE. DOI: 10.1371/journal.pone.0164660 [Hes1, PlexinD1promoter clones]
• Trueba-Saiz, A., et al. (2016). Circulating Insulin-like Growth Factor I Regulates Its Receptor in the Brain of Male Mice. Endocrinology. DOI:  10.1210/en.2016-1468 [IGF-IR promoter-Gaussia luciferase reporter lentiviral clone]
• Chu, Q., et al. (2016). Extracellular serglycin upregulates the CD44 receptor in an autocrine manner to maintain self-renewal in nasopharyngeal carcinoma cells by reciprocally activating the MAPK/β-catenin axis. Cell Death and Disease. DOI: 10.1038/cddis.2016.287 [GLuc-ON™ CD44 promoter-reporter clone]
• Xiang, S., et al. (2016). Activation of AMPKα mediates additive effects of solamargine and metformin on suppressing MUC1 expression in castration-resistant prostate cancer cells. Scientific Reports. DOI:10.1038/srep36721 [GLuc-ON™ MUC1 promoter-reporter clone]
• Holler, et al. (2016). Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia. Molecular Neurodegeneration. DOI: 10.1186/s13024-016-0114-3  [GLuc-ON™ PGRN promoter-reporter clone]
• Revandkar, A., et al. (2016). Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence. Nature Communications. DOI: 10.1038/ncomms13719 [GLuc-ON™ ADAM7 promoter clone]
• Xie, X., et al. (2016). c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun. Oncogene. DOI: 10.1038/onc.2016.417  [GLuc-ON™ Notch1 promoter-reporter clone]

• Natunen, T., et al. (2015) Relationship between ubiquilin-1 and BACE1 in human Alzheimer’s disease and APdE9 transgenic mouse brain and cell-based models. Neurobiology of disease,DOI: 10.1016/j.nbd.2015.11.005 [human BACE1 containing endogenous 5′UTR, BACE1-Myc (human BACE1 with a CMV promoter and a 3′-myc-tag sequence producing BACE1 protein containing a myc tag in the C-terminus)]
• C Authors, R Trivedi ., et al. (2015) JBC Papers in Press. Published on December 9, 2015 as Manuscript M115. 687152. JBC,http://www.jbc.org/cgi/doi/10.1074/jbc.M115.687152 [Runx2 promoter clones (Cat# MPRM13038)]
• Muralidharan, R., et al. (2015) HuR-targeted nanotherapy in combination with AMD3100 suppresses CXCR4 expression, cell growth, migration and invasion in lung cancer. Cancer Gene Therapy, ancer Gene Therapy (2015) 22, 581–590. DOI:10.1038/cgt.2015.55 [Promotor reporter clone for CXCR4]
• Maeng, YS., et al. (2015) TGFBIp regulates differentiation of EPC (CD133+ C‐kit+ Lin‐cells) to EC through activation of the Notch signaling pathway. STEM CELLS DOI: 10.1002/stem.2003. [pEZX-DLL1 pro- moter luciferase plasmids (-1.2 Kbp)]
• Li, C., et al. (2015) Noncanonical STAT3 Activation Regulates Excess TGF-β1 and Collagen I Expression in Muscle of Stricturing Crohn’s Disease. The Journal of Immunology. DOI: 10.4049/​jimmunol.1401779 [promoter reporter clone for human TGFB1 (HPRM13178-PG04), EndoFectin Lenti transfection reagent (EFP1003)]
• Zhang , Z., et al. (2015) BET Bromodomain Inhibition as a Therapeutic Strategy in Ovarian Cancer by Downregulating FoxM1. Theranostics. DOI:10.7150/thno.13178 [human FoxM1 promoter clone]

• Ryu , JM., et al. (2014) Autotaxin‐LPA Axis regulates hMSC migration by adherent junction disruption and cytoskeletal rearrangement via LPAR1/3‐dependent PKC/GSK3β/β‐catenin and PKC/Rho GTPase Pathways . STEM CELLS. DOI: 10.1002/stem.1882 [CDH-1 promoter construct]
• Zhang, H., et al. (2014) The critical role of myeloid-derived suppressor cells and FXR activation in immune-mediated liver injury. Journal of Autoimmunity. DOI: 10.1016/j.jaut.2014.02.010 [MPRM11909-PG04]
• Rubie, C., et al. (2014) Chemokine receptor CCR6 expression is regulated by miR-518a-5p in colorectal cancer cells. Journal of translational medicine, 2014 Feb 21;12:48. DOI: 10.1186/1479-5876-12-48 [Luc CCR6 vector, Luc No CCR6 vector]

• Klimosch, SN., et al (2013) Functional TLR5 genetic variants affect human colorectal cancer survival. Cancer Research, 73(24); 7232–42 [Promoter Reporter ( MYD88 and ACAA1)]
• Shen, Q., et al (2013) Adipocyte reporter assays: Application for identification of anti‐inflammatory and antioxidant properties of mangosteen xanthones. Molecular Nutrition & Food Research, DOI: 10.1002/mnfr.201300181 [Human Fabp4 promoter vector with eCFP reporter]
• Celardo, I., et al. (2013) Caspase-1 is a novel target of p63 in tumor suppression. Cell Death and Disease (2013) 4, e645;. DOI:10.1038/cddis.2013.175 [caspase-1 promoter plasmid in pEZX-PG02 vector]
• Zheng, H., et al. (2013) Glycogen synthase kinase-3 beta regulates Snail and β-catenin expression during Fas-induced epithelial–mesenchymal transition in gastrointestinal cancer. European Journal of Cancer, Available online 9 April 2013 [CDH1 promoter construct]
• Mills, L.D., et al. (2013) Loss of the Transcription Factor GLI1 Identifies a Signaling Network in the Tumor Microenvironment Mediating KRAS-Induced. Journal of Biological Chemistry, March 12, 2013,. DOI: 10.1074/jbc.M112.438846 [mouse SHH promoter clone]
• Schank, JR., et al (2013)  Tacr1 Gene Variation and Neurokinin 1 Receptor Expression Is Associated with Antagonist Efficacy in Genetically Selected Alcohol-Preferring Rats. Biological Psychiatry Journal, PII: S0006-3223(13)00043-7. DOI:10.1016/j.biopsych.2012.12.027 [custom Tacr1 promoter luciferase construct]

• Petrella, B., et al. (2012) Interleukin-1 beta and transforming growth factor-beta 3 cooperate to activate matrix metalloproteinase expression and invasiveness in A549 lung adenocarcinoma Cancer Letters, Volume 325, Issue 2, 28 December 2012, Pages 220–226 [MMP10 promoter clone]

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